Gene name: GRX2
Reference locus (S288C): YDR513W
Gene biotype: protein_coding
Description: Glutaredoxin-2, mitochondrial; Cytoplasmic glutaredoxin; thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress; GRX2 has two in-frame start codons resulting in a shorter isoform that is retained in the cytosol and a longer form translocated to the mitochondrial matrix; GRX2 has a paralog, GRX1, that arose from the whole genome duplication
Top 10 interactors (score): GRX5 (0.975); TRX2 (0.973); TRX1 (0.967); PRX1 (0.966); GRX3 (0.962); HYR1 (0.952); GLR1 (0.95); GPX1 (0.93); GPX2 (0.919); YET3 (0.916); YDL124W (0.914); TRX3 (0.886); TRR1 (0.886); GSH1 (0.879); TSA1 (0.874); ETR1 (0.868); CTT1 (0.862); GRX4 (0.855); NOP4 (0.855); ISA1 (0.843)
Homologues (species, bitscore): GLRX2 (Homo sapiens, 71.6); Glrx2 (Mus musculus, 72.4); txnrd1 (Danio rerio, 82.4); txnrd3 (Xenopus tropicalis, 80.5); Grx-1 (Drosophila melanogaster, 81.3); glrx-10 (Caenorhabditis elegans, 80.9); AT5G20500 (Arabidopsis thaliana, 87.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1411026-1411457:+ | gene-YDR513W_AKU4011 | rna-NM_001180821.1_AKU4011 | cds-NP_010801.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:52678-53109:+ | gene-YDR513W_BG1 | rna-NM_001180821.1_BG1 | cds-NP_010801.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1442342-1442773:+ | gene-YDR513W_Bruggeman | rna-NM_001180821.1_Bruggeman | cds-NP_010801.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1419520-1419951:+ | gene-YDR513W_CAT1 | rna-NM_001180821.1_CAT1 | cds-NP_010801.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1405761-1406192:+ | gene-YDR513W_CBS1585 | rna-NM_001180821.1_CBS1585 | cds-NP_010801.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1424989-1425420:+ | gene-YDR513W_CBS436 | rna-NM_001180821.1_CBS436 | cds-NP_010801.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1400911-1401342:+ | gene-YDR513W_CBS6412 | rna-NM_001180821.1_CBS6412 | cds-NP_010801.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1424415-1424846:+ | gene-YDR513W_CBS6413 | rna-NM_001180821.1_CBS6413 | cds-NP_010801.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1469708-1470139:+ | gene-YDR513W_CENPK1137D | rna-NM_001180821.1_CENPK1137D | cds-NP_010801.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1414293-1414724:+ | gene-YDR513W_EthanolRed | rna-NM_001180821.1_EthanolRed | cds-NP_010801.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1417845-1418276:+ | gene-YDR513W_FaliES1 | rna-NM_001180821.1_FaliES1 | cds-NP_010801.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:116221-116652:+ | gene-YDR513W_JAY291 | rna-NM_001180821.1_JAY291 | cds-NP_010801.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1425434-1425865:+ | gene-YDR513W_MUCL30387 | rna-NM_001180821.1_MUCL30387 | cds-NP_010801.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1406866-1407297:+ | gene-YDR513W_MUCL30388 | rna-NM_001180821.1_MUCL30388 | cds-NP_010801.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1397250-1397681:+ | gene-YDR513W_MUCL39482 | rna-NM_001180821.1_MUCL39482 | cds-NP_010801.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1339911-1340342:+ | gene-YDR513W_MUCL42920 | rna-NM_001180821.1_MUCL42920 | cds-NP_010801.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1470940-1471371:+ | gene-YDR513W_NCIM3186 | rna-NM_001180821.1_NCIM3186 | cds-NP_010801.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1410540-1410971:+ | gene-YDR513W_NCYC1407 | rna-NM_001180821.1_NCYC1407 | cds-NP_010801.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1421488-1421919:+ | gene-YDR513W_PE2H3 | rna-NM_001180821.1_PE2H3 | cds-NP_010801.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1426956-1427387:+ | gene-YDR513W_PE2H4 | rna-NM_001180821.1_PE2H4 | cds-NP_010801.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1471017-1471448:+ | gene-YDR513W_S288C | rna-NM_001180821.1_S288C | cds-NP_010801.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:145669-146100:- | gene-YDR513W_SA1 | rna-NM_001180821.1_SA1 | cds-NP_010801.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1422067-1422498:+ | gene-YDR513W_ThermosaccDry | rna-NM_001180821.1_ThermosaccDry | cds-NP_010801.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1437859-1438290:+ | gene-YDR513W_VR1 | rna-NM_001180821.1_VR1 | cds-NP_010801.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:464727-465158:+ | gene-YDR513W_ZTW1 | rna-NM_001180821.1_ZTW1 | cds-NP_010801.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1430994-1431425:+ | gene-YDR513W_Sparadoxus | rna-NM_001180821.1_Sparadoxus | cds-NP_010801.1_Sparadoxus | 92.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |