Gene name: GRX1
Reference locus (S288C): YCL035C
Gene biotype: protein_coding
Description: Glutaredoxin-1; Glutathione-dependent disulfide oxidoreductase; hydroperoxide and superoxide-radical responsive, heat-stable, with active site cysteine pair; protects cells from oxidative damage; GRX1 has a paralog, GRX2, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): TRX1 (0.968); TRX2 (0.964); GLR1 (0.951); GRX5 (0.946); GRX3 (0.941); GPX1 (0.934); GPX2 (0.91); YDL124W (0.91); YET3 (0.902); HYR1 (0.894); ETR1 (0.87); NOP4 (0.855); PRX1 (0.846); TSA2 (0.844); TRR1 (0.842); AHP1 (0.824); CTT1 (0.82); GRX7 (0.814); MXR2 (0.802); TSA1 (0.794)
Homologues (species, bitscore): GLRX2 (Homo sapiens, 67.0); Txnrd3 (Mus musculus, 72.4); txnrd1 (Danio rerio, 75.5); txnrd3 (Xenopus tropicalis, 76.3); CG6852 (Drosophila melanogaster, 86.7); glrx-10 (Caenorhabditis elegans, 70.9); AT5G20500 (Arabidopsis thaliana, 91.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:62203-62535:- | gene-YCL035C_AKU4011 | rna-NM_001178680.1_AKU4011 | cds-NP_009895.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000178.1:84578-84910:+ | gene-YCL035C_BG1 | rna-NM_001178680.1_BG1 | cds-NP_009895.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:50394-50726:- | gene-YCL035C_Bruggeman | rna-NM_001178680.1_Bruggeman | cds-NP_009895.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:61999-62331:- | gene-YCL035C_CAT1 | rna-NM_001178680.1_CAT1 | cds-NP_009895.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:62890-63222:- | gene-YCL035C_CBS1585 | rna-NM_001178680.1_CBS1585 | cds-NP_009895.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:61337-61669:- | gene-YCL035C_CBS436 | rna-NM_001178680.1_CBS436 | cds-NP_009895.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:50292-50624:- | gene-YCL035C_CBS6412 | rna-NM_001178680.1_CBS6412 | cds-NP_009895.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:61664-61996:- | gene-YCL035C_CBS6413 | rna-NM_001178680.1_CBS6413 | cds-NP_009895.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:60438-60770:- | gene-YCL035C_CENPK1137D | rna-NM_001178680.1_CENPK1137D | cds-NP_009895.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:60226-60558:- | gene-YCL035C_EthanolRed | rna-NM_001178680.1_EthanolRed | cds-NP_009895.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:61166-61498:- | gene-YCL035C_FaliES1 | rna-NM_001178680.1_FaliES1 | cds-NP_009895.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000225.1:22885-23217:+ | gene-YCL035C_JAY291 | rna-NM_001178680.1_JAY291 | cds-NP_009895.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:48590-48922:- | gene-YCL035C_MUCL30387 | rna-NM_001178680.1_MUCL30387 | cds-NP_009895.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:48863-49195:- | gene-YCL035C_MUCL30388 | rna-NM_001178680.1_MUCL30388 | cds-NP_009895.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:63259-63591:- | gene-YCL035C_MUCL39482 | rna-NM_001178680.1_MUCL39482 | cds-NP_009895.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:49375-49707:- | gene-YCL035C_MUCL42920 | rna-NM_001178680.1_MUCL42920 | cds-NP_009895.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:60473-60805:- | gene-YCL035C_NCIM3186 | rna-NM_001178680.1_NCIM3186 | cds-NP_009895.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:63747-64079:- | gene-YCL035C_NCYC1407 | rna-NM_001178680.1_NCYC1407 | cds-NP_009895.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:61294-61626:- | gene-YCL035C_PE2H3 | rna-NM_001178680.1_PE2H3 | cds-NP_009895.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:61251-61583:- | gene-YCL035C_PE2H4 | rna-NM_001178680.1_PE2H4 | cds-NP_009895.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:60841-61173:- | gene-YCL035C_S288C | rna-NM_001178680.1_S288C | cds-NP_009895.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000061.1:47979-48311:- | gene-YCL035C_SA1 | rna-NM_001178680.1_SA1 | cds-NP_009895.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:61487-61819:- | gene-YCL035C_ThermosaccDry | rna-NM_001178680.1_ThermosaccDry | cds-NP_009895.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:67783-68115:- | gene-YCL035C_VR1 | rna-NM_001178680.1_VR1 | cds-NP_009895.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:61687-62019:- | gene-YCL035C_ZTW1 | rna-NM_001178680.1_ZTW1 | cds-NP_009895.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:91208-91540:- | gene-YCL035C_Sparadoxus | rna-NM_001178680.1_Sparadoxus | cds-NP_009895.1_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |