Gene name: GRS2
Reference locus (S288C): YPR081C
Gene biotype: protein_coding
Description: Glycine--tRNA ligase 2; Glycine-tRNA synthetase, not expressed under normal growth conditions; expression is induced under heat, oxidative, pH, or ethanol stress conditions; more stable than the major glycine-tRNA synthetase Grs1p at 37 deg C; GRS2 has a paralog, GRS1, that arose from the whole genome duplication
Top 10 interactors (score): ILS1 (0.973); THS1 (0.962); SES1 (0.948); TEF4 (0.907); CAM1 (0.907); ALA1 (0.9); GUS1 (0.894); MIP1 (0.891); MST1 (0.888); TYS1 (0.88); CCT5 (0.879); DPS1 (0.864); GRS1 (0.859); ARC1 (0.85); YHR020W (0.835); CDC60 (0.832); DIA4 (0.82); KRS1 (0.786); DED81 (0.772); VAS1 (0.758)
Homologues (species, bitscore): GARS (Homo sapiens, 607.1); Gars (Mus musculus, 605.9); gars (Danio rerio, 609.8); gars (Xenopus tropicalis, 594.7); Aats-gly (Drosophila melanogaster, 622.9); gars-1 (Caenorhabditis elegans, 583.9); AT1G29880 (Arabidopsis thaliana, 575.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:673796-675652:- | gene-YPR081C_AKU4011 | rna-NM_001184178.1_AKU4011 | cds-NP_015406.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:222028-223884:+ | gene-YPR081C_BG1 | rna-NM_001184178.1_BG1 | cds-NP_015406.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:751475-753331:- | gene-YPR081C_Bruggeman | rna-NM_001184178.1_Bruggeman | cds-NP_015406.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:795776-797632:- | gene-YPR081C_CAT1 | rna-NM_001184178.1_CAT1 | cds-NP_015406.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:677722-679578:- | gene-YPR081C_CBS1585 | rna-NM_001184178.1_CBS1585 | cds-NP_015406.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:692347-694203:- | gene-YPR081C_CBS436 | rna-NM_001184178.1_CBS436 | cds-NP_015406.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:680858-682714:- | gene-YPR081C_CBS6412 | rna-NM_001184178.1_CBS6412 | cds-NP_015406.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:674679-676535:- | gene-YPR081C_CBS6413 | rna-NM_001184178.1_CBS6413 | cds-NP_015406.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:702093-703949:- | gene-YPR081C_CENPK1137D | rna-NM_001184178.1_CENPK1137D | cds-NP_015406.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1000796-1002652:- | gene-YPR081C_EthanolRed | rna-NM_001184178.1_EthanolRed | cds-NP_015406.1_EthanolRed | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:679629-681485:- | gene-YPR081C_FaliES1 | rna-NM_001184178.1_FaliES1 | cds-NP_015406.1_FaliES1 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000094.1:1521-3377:- | gene-YPR081C_JAY291 | rna-NM_001184178.1_JAY291 | cds-NP_015406.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:692734-694590:- | gene-YPR081C_MUCL30387 | rna-NM_001184178.1_MUCL30387 | cds-NP_015406.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:691438-693294:- | gene-YPR081C_MUCL30388 | rna-NM_001184178.1_MUCL30388 | cds-NP_015406.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:670729-672585:- | gene-YPR081C_MUCL39482 | rna-NM_001184178.1_MUCL39482 | cds-NP_015406.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:733575-735431:- | gene-YPR081C_MUCL42920 | rna-NM_001184178.1_MUCL42920 | cds-NP_015406.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:702097-703953:- | gene-YPR081C_NCIM3186 | rna-NM_001184178.1_NCIM3186 | cds-NP_015406.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:679155-681011:- | gene-YPR081C_NCYC1407 | rna-NM_001184178.1_NCYC1407 | cds-NP_015406.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:685557-687413:- | gene-YPR081C_PE2H3 | rna-NM_001184178.1_PE2H3 | cds-NP_015406.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:685205-687061:- | gene-YPR081C_PE2H4 | rna-NM_001184178.1_PE2H4 | cds-NP_015406.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:702114-703970:- | gene-YPR081C_S288C | rna-NM_001184178.1_S288C | cds-NP_015406.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000028.1:234-2090:- | gene-YPR081C_SA1 | rna-NM_001184178.1_SA1 | cds-NP_015406.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:679404-681260:- | gene-YPR081C_ThermosaccDry | rna-NM_001184178.1_ThermosaccDry | cds-NP_015406.1_ThermosaccDry | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:696045-697901:- | gene-YPR081C_VR1 | rna-NM_001184178.1_VR1 | cds-NP_015406.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:678623-680479:- | gene-YPR081C_ZTW1 | rna-NM_001184178.1_ZTW1 | cds-NP_015406.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:679318-681174:- | gene-YPR081C_Sparadoxus | rna-NM_001184178.1_Sparadoxus | cds-NP_015406.1_Sparadoxus | 88.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |