Gene name: GRR1
Reference locus (S288C): YJR090C
Gene biotype: protein_coding
Description: F-box protein component of an SCF ubiquitin-ligase complex; modular substrate specificity factor which associates with core SCF (Cdc53p, Skp1p and Hrt1p/Rbx1p) to form the SCF(Grr1) complex; SCF(Grr1) acts as a ubiquitin-protein ligase directing ubiquitination of substrates such as: Gic2p, Mks1p, Mth1p, Cln1p, Cln2p and Cln3p; involved in carbon catabolite repression, glucose-dependent divalent cation transport, glucose transport, morphogenesis, and sulfite detoxification
Top 10 interactors (score): SKP1 (0.999); CDC53 (0.999); CLN2 (0.993); HRT1 (0.99); CDC4 (0.98); MET30 (0.98); RGT1 (0.971); CLN1 (0.962); PFK27 (0.936); CDC34 (0.919); REG1 (0.864); HOF1 (0.863); SNF3 (0.842); CDC28 (0.829); SSY5 (0.827); MKS1 (0.817); SSN2 (0.798); BMH2 (0.797); STD1 (0.796); SNF1 (0.781)
Homologues (species, bitscore): FBXL20 (Homo sapiens, 112.5); Fbxl20 (Mus musculus, 113.2); fbxl20 (Danio rerio, 122.5); fbxl20 (Xenopus tropicalis, 107.8); CG9003 (Drosophila melanogaster, 125.9); C02F5.7 (Caenorhabditis elegans, 100.9); AT4G15475 (Arabidopsis thaliana, 100.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:562401-565847:- | gene-YJR090C_AKU4011 | rna-NM_001181747.1_AKU4011 | cds-NP_012623.1_AKU4011 | 99.4 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:41728-45171:+ | gene-YJR090C_BG1 | rna-NM_001181747.1_BG1 | cds-NP_012623.1_BG1 | 99.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:575915-579361:- | gene-YJR090C_Bruggeman | rna-NM_001181747.1_Bruggeman | cds-NP_012623.1_Bruggeman | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:580314-583757:- | gene-YJR090C_CAT1 | rna-NM_001181747.1_CAT1 | cds-NP_012623.1_CAT1 | 99.1 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:574465-577911:- | gene-YJR090C_CBS1585 | rna-NM_001181747.1_CBS1585 | cds-NP_012623.1_CBS1585 | 99.4 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:592554-595997:- | gene-YJR090C_CBS436 | rna-NM_001181747.1_CBS436 | cds-NP_012623.1_CBS436 | 99.1 | 99.6 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:561613-565059:- | gene-YJR090C_CBS6412 | rna-NM_001181747.1_CBS6412 | cds-NP_012623.1_CBS6412 | 99.4 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:563907-567353:- | gene-YJR090C_CBS6413 | rna-NM_001181747.1_CBS6413 | cds-NP_012623.1_CBS6413 | 99.2 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:573228-576671:- | gene-YJR090C_CENPK1137D | rna-NM_001181747.1_CENPK1137D | cds-NP_012623.1_CENPK1137D | 99.1 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:566791-570246:- | gene-YJR090C_EthanolRed | rna-NM_001181747.1_EthanolRed | cds-NP_012623.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:578257-581712:- | gene-YJR090C_FaliES1 | rna-NM_001181747.1_FaliES1 | cds-NP_012623.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:107685-111128:+ | gene-YJR090C_JAY291 | rna-NM_001181747.1_JAY291 | cds-NP_012623.1_JAY291 | 99.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:576445-579891:- | gene-YJR090C_MUCL30387 | rna-NM_001181747.1_MUCL30387 | cds-NP_012623.1_MUCL30387 | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:573741-577187:- | gene-YJR090C_MUCL30388 | rna-NM_001181747.1_MUCL30388 | cds-NP_012623.1_MUCL30388 | 99.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:567925-571371:- | gene-YJR090C_MUCL39482 | rna-NM_001181747.1_MUCL39482 | cds-NP_012623.1_MUCL39482 | 99.4 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:572171-575617:- | gene-YJR090C_MUCL42920 | rna-NM_001181747.1_MUCL42920 | cds-NP_012623.1_MUCL42920 | 99.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:590851-594306:- | gene-YJR090C_NCIM3186 | rna-NM_001181747.1_NCIM3186 | cds-NP_012623.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:565491-568937:- | gene-YJR090C_NCYC1407 | rna-NM_001181747.1_NCYC1407 | cds-NP_012623.1_NCYC1407 | 99.3 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:583388-586831:- | gene-YJR090C_PE2H3 | rna-NM_001181747.1_PE2H3 | cds-NP_012623.1_PE2H3 | 99.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:577077-580520:- | gene-YJR090C_PE2H4 | rna-NM_001181747.1_PE2H4 | cds-NP_012623.1_PE2H4 | 99.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:590872-594327:- | gene-YJR090C_S288C | rna-NM_001181747.1_S288C | cds-NP_012623.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000038.1:49453-52896:- | gene-YJR090C_SA1 | rna-NM_001181747.1_SA1 | cds-NP_012623.1_SA1 | 99.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:572191-575646:- | gene-YJR090C_ThermosaccDry | rna-NM_001181747.1_ThermosaccDry | cds-NP_012623.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:574346-577789:- | gene-YJR090C_VR1 | rna-NM_001181747.1_VR1 | cds-NP_012623.1_VR1 | 99.3 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:551585-555031:- | gene-YJR090C_ZTW1 | rna-NM_001181747.1_ZTW1 | cds-NP_012623.1_ZTW1 | 99.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:584987-588433:- | gene-YJR090C_Sparadoxus | rna-NM_001181747.1_Sparadoxus | cds-NP_012623.1_Sparadoxus | 90.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |