GRH1 (YDR517W)


Gene profile

Gene name: GRH1
Reference locus (S288C): YDR517W
Gene biotype: protein_coding

Description: GRASP65 homolog protein 1; Acetylated cis-Golgi protein, involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): BUG1 (0.996); USO1 (0.987); YPT1 (0.986); ACB1 (0.969); SEC24 (0.968); SLY1 (0.964); CDC5 (0.957); SEC23 (0.945); SED5 (0.936); RUD3 (0.919); SEC13 (0.916); COY1 (0.876); SEC12 (0.843); GOS1 (0.828); SEC22 (0.822); SFB2 (0.774); SEC18 (0.757); ARL3 (0.738); STP22 (0.73); SEC1 (0.716)

Homologues (species, bitscore): GORASP1 (Homo sapiens, 69.7); Gorasp1 (Mus musculus, 73.2); gorasp2 (Danio rerio, 68.9); gorasp1 (Xenopus tropicalis, 61.2); Grasp65 (Drosophila melanogaster, 63.9); Y42H9AR.1 (Caenorhabditis elegans, 71.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1417250-1418380:+ gene-YDR517W_AKU4011 rna-NM_001180825.1_AKU4011 cds-NP_010805.1_AKU4011 98.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000073.1:58905-60023:+ gene-YDR517W_BG1 rna-NM_001180825.1_BG1 cds-NP_010805.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1448564-1449688:+ gene-YDR517W_Bruggeman rna-NM_001180825.1_Bruggeman cds-NP_010805.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1425741-1426859:+ gene-YDR517W_CAT1 rna-NM_001180825.1_CAT1 cds-NP_010805.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1411976-1413106:+ gene-YDR517W_CBS1585 rna-NM_001180825.1_CBS1585 cds-NP_010805.1_CBS1585 98.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1431216-1432334:+ gene-YDR517W_CBS436 rna-NM_001180825.1_CBS436 cds-NP_010805.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1407135-1408271:+ gene-YDR517W_CBS6412 rna-NM_001180825.1_CBS6412 cds-NP_010805.1_CBS6412 98.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1430638-1431768:+ gene-YDR517W_CBS6413 rna-NM_001180825.1_CBS6413 cds-NP_010805.1_CBS6413 98.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1475929-1477047:+ gene-YDR517W_CENPK1137D rna-NM_001180825.1_CENPK1137D cds-NP_010805.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1420515-1421639:+ gene-YDR517W_EthanolRed rna-NM_001180825.1_EthanolRed cds-NP_010805.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1424067-1425191:+ gene-YDR517W_FaliES1 rna-NM_001180825.1_FaliES1 cds-NP_010805.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:122442-123560:+ gene-YDR517W_JAY291 rna-NM_001180825.1_JAY291 cds-NP_010805.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1431660-1432778:+ gene-YDR517W_MUCL30387 rna-NM_001180825.1_MUCL30387 cds-NP_010805.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1413088-1414212:+ gene-YDR517W_MUCL30388 rna-NM_001180825.1_MUCL30388 cds-NP_010805.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1403474-1404604:+ gene-YDR517W_MUCL39482 rna-NM_001180825.1_MUCL39482 cds-NP_010805.1_MUCL39482 98.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1346139-1347257:+ gene-YDR517W_MUCL42920 rna-NM_001180825.1_MUCL42920 cds-NP_010805.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1477162-1478280:+ gene-YDR517W_NCIM3186 rna-NM_001180825.1_NCIM3186 cds-NP_010805.1_NCIM3186 99.9 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1416766-1417896:+ gene-YDR517W_NCYC1407 rna-NM_001180825.1_NCYC1407 cds-NP_010805.1_NCYC1407 98.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1427711-1428829:+ gene-YDR517W_PE2H3 rna-NM_001180825.1_PE2H3 cds-NP_010805.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1433179-1434297:+ gene-YDR517W_PE2H4 rna-NM_001180825.1_PE2H4 cds-NP_010805.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1477239-1478357:+ gene-YDR517W_S288C rna-NM_001180825.1_S288C cds-NP_010805.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:138755-139873:- gene-YDR517W_SA1 rna-NM_001180825.1_SA1 cds-NP_010805.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1428289-1429413:+ gene-YDR517W_ThermosaccDry rna-NM_001180825.1_ThermosaccDry cds-NP_010805.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1444086-1445204:+ gene-YDR517W_VR1 rna-NM_001180825.1_VR1 cds-NP_010805.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:470951-472075:+ gene-YDR517W_ZTW1 rna-NM_001180825.1_ZTW1 cds-NP_010805.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1437238-1438350:+ gene-YDR517W_Sparadoxus rna-NM_001180825.1_Sparadoxus cds-NP_010805.1_Sparadoxus 88.0 99.3 Verified 1 1 1 False True False False False

Additional files