GPX1 (YKL026C)


Gene profile

Gene name: GPX1
Reference locus (S288C): YKL026C
Gene biotype: protein_coding

Description: Glutathione peroxidase-like peroxiredoxin 1; Phospholipid hydroperoxide glutathione peroxidase; induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress; GPX1 has a paralog, HYR1, that arose from the whole genome duplication

Top 10 interactors (score): GLR1 (0.993); CTT1 (0.962); PRX1 (0.942); GRX1 (0.934); GRX2 (0.93); TSA2 (0.928); AHP1 (0.92); CTA1 (0.917); TSA1 (0.916); SOD2 (0.903); YAP1 (0.884); SOD1 (0.883); TRX3 (0.881); TRX2 (0.877); TRX1 (0.871); UIP4 (0.868); GSH1 (0.868); TRR1 (0.862); SRX1 (0.847); DOT5 (0.822)

Homologues (species, bitscore): GPX7 (Homo sapiens, 106.7); Gpx7 (Mus musculus, 108.6); gpx8 (Danio rerio, 108.6); gpx7 (Xenopus tropicalis, 97.8); PHGPx (Drosophila melanogaster, 110.9); F26E4.12 (Caenorhabditis elegans, 122.5); GPX6 (Arabidopsis thaliana, 145.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:375398-375901:- gene-YKL026C_AKU4011 rna-NM_001179592.3_AKU4011 cds-NP_012899.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:268007-268510:+ gene-YKL026C_BG1 rna-NM_001179592.3_BG1 cds-NP_012899.3_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:397093-397596:- gene-YKL026C_Bruggeman rna-NM_001179592.3_Bruggeman cds-NP_012899.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:392208-392711:- gene-YKL026C_CAT1 rna-NM_001179592.3_CAT1 cds-NP_012899.3_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:388117-388620:- gene-YKL026C_CBS1585 rna-NM_001179592.3_CBS1585 cds-NP_012899.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:386967-387470:- gene-YKL026C_CBS436 rna-NM_001179592.3_CBS436 cds-NP_012899.3_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:372273-372776:- gene-YKL026C_CBS6412 rna-NM_001179592.3_CBS6412 cds-NP_012899.3_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:387972-388475:- gene-YKL026C_CBS6413 rna-NM_001179592.3_CBS6413 cds-NP_012899.3_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:389057-389560:- gene-YKL026C_CENPK1137D rna-NM_001179592.3_CENPK1137D cds-NP_012899.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:385894-386397:- gene-YKL026C_EthanolRed rna-NM_001179592.3_EthanolRed cds-NP_012899.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:387984-388487:- gene-YKL026C_FaliES1 rna-NM_001179592.3_FaliES1 cds-NP_012899.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000142.1:42564-43067:+ gene-YKL026C_JAY291 rna-NM_001179592.3_JAY291 cds-NP_012899.3_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:396408-396911:- gene-YKL026C_MUCL30387 rna-NM_001179592.3_MUCL30387 cds-NP_012899.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:392017-392520:- gene-YKL026C_MUCL30388 rna-NM_001179592.3_MUCL30388 cds-NP_012899.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:387434-387937:- gene-YKL026C_MUCL39482 rna-NM_001179592.3_MUCL39482 cds-NP_012899.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:393261-393764:- gene-YKL026C_MUCL42920 rna-NM_001179592.3_MUCL42920 cds-NP_012899.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:389369-389872:- gene-YKL026C_NCIM3186 rna-NM_001179592.3_NCIM3186 cds-NP_012899.3_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:387626-388129:- gene-YKL026C_NCYC1407 rna-NM_001179592.3_NCYC1407 cds-NP_012899.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:412313-412816:- gene-YKL026C_PE2H3 rna-NM_001179592.3_PE2H3 cds-NP_012899.3_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:397059-397562:- gene-YKL026C_PE2H4 rna-NM_001179592.3_PE2H4 cds-NP_012899.3_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:389380-389883:- gene-YKL026C_S288C rna-NM_001179592.3_S288C cds-NP_012899.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000027.1:67659-68162:- gene-YKL026C_SA1 rna-NM_001179592.3_SA1 cds-NP_012899.3_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:388083-388586:- gene-YKL026C_ThermosaccDry rna-NM_001179592.3_ThermosaccDry cds-NP_012899.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:387338-387841:- gene-YKL026C_VR1 rna-NM_001179592.3_VR1 cds-NP_012899.3_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:386111-386614:- gene-YKL026C_ZTW1 rna-NM_001179592.3_ZTW1 cds-NP_012899.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:405694-406197:- gene-YKL026C_Sparadoxus rna-NM_001179592.3_Sparadoxus cds-NP_012899.3_Sparadoxus 88.6 100.0 Verified 1 1 1 False True False False False

Additional files