Gene name: GPN3
Reference locus (S288C): YLR243W
Gene biotype: protein_coding
Description: GPN-loop GTPase 3; Putative GTPase with a role in biogenesis of RNA pol II and polIII; may be involved in assembly of RNA polymerases II and III and in their transport into the nucleus; may have a role in sister chromatid cohesion; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively; contains a Gly-Pro-Asn motif in the G domain; similar to Npa3p and Gpn2p
Top 10 interactors (score): NPA3 (0.989); RPB5 (0.944); RPB10 (0.932); RPB3 (0.928); NOC3 (0.912); IWR1 (0.909); NBP35 (0.894); VPS75 (0.892); SRB7 (0.892); RPC19 (0.891); TFB3 (0.887); HUB1 (0.883); RPO26 (0.874); TAN1 (0.872); RPC10 (0.871); RPB2 (0.845); IMP3 (0.836); RBA50 (0.823); TCP1 (0.82); RPO21 (0.812)
Homologues (species, bitscore): GPN3 (Homo sapiens, 235.7); Gpn3 (Mus musculus, 252.3); gpn3 (Danio rerio, 258.1); gpn3 (Xenopus tropicalis, 253.8); CG2656 (Drosophila melanogaster, 221.1); Y75B8A.14 (Caenorhabditis elegans, 235.7); AT4G12790 (Arabidopsis thaliana, 270.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:578413-579231:+ | gene-YLR243W_AKU4011 | rna-NM_001182130.1_AKU4011 | cds-NP_013344.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:152680-153498:- | gene-YLR243W_BG1 | rna-NM_001182130.1_BG1 | cds-NP_013344.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:612648-613466:+ | gene-YLR243W_Bruggeman | rna-NM_001182130.1_Bruggeman | cds-NP_013344.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:611772-612590:+ | gene-YLR243W_CAT1 | rna-NM_001182130.1_CAT1 | cds-NP_013344.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:613908-614726:+ | gene-YLR243W_CBS1585 | rna-NM_001182130.1_CBS1585 | cds-NP_013344.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:598114-598932:+ | gene-YLR243W_CBS436 | rna-NM_001182130.1_CBS436 | cds-NP_013344.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:576883-577701:+ | gene-YLR243W_CBS6412 | rna-NM_001182130.1_CBS6412 | cds-NP_013344.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:614203-615021:+ | gene-YLR243W_CBS6413 | rna-NM_001182130.1_CBS6413 | cds-NP_013344.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:608814-609632:+ | gene-YLR243W_CENPK1137D | rna-NM_001182130.1_CENPK1137D | cds-NP_013344.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:571947-572765:+ | gene-YLR243W_EthanolRed | rna-NM_001182130.1_EthanolRed | cds-NP_013344.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:600872-601690:+ | gene-YLR243W_FaliES1 | rna-NM_001182130.1_FaliES1 | cds-NP_013344.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000136.1:57200-58018:- | gene-YLR243W_JAY291 | rna-NM_001182130.1_JAY291 | cds-NP_013344.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:613505-614323:+ | gene-YLR243W_MUCL30387 | rna-NM_001182130.1_MUCL30387 | cds-NP_013344.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:617627-618445:+ | gene-YLR243W_MUCL30388 | rna-NM_001182130.1_MUCL30388 | cds-NP_013344.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:614889-615707:+ | gene-YLR243W_MUCL39482 | rna-NM_001182130.1_MUCL39482 | cds-NP_013344.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:609648-610466:+ | gene-YLR243W_MUCL42920 | rna-NM_001182130.1_MUCL42920 | cds-NP_013344.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:624177-624995:+ | gene-YLR243W_NCIM3186 | rna-NM_001182130.1_NCIM3186 | cds-NP_013344.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:601875-602693:+ | gene-YLR243W_NCYC1407 | rna-NM_001182130.1_NCYC1407 | cds-NP_013344.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:605592-606410:+ | gene-YLR243W_PE2H3 | rna-NM_001182130.1_PE2H3 | cds-NP_013344.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:605336-606154:+ | gene-YLR243W_PE2H4 | rna-NM_001182130.1_PE2H4 | cds-NP_013344.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:624203-625021:+ | gene-YLR243W_S288C | rna-NM_001182130.1_S288C | cds-NP_013344.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:57451-58269:- | gene-YLR243W_SA1 | rna-NM_001182130.1_SA1 | cds-NP_013344.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:603372-604190:+ | gene-YLR243W_ThermosaccDry | rna-NM_001182130.1_ThermosaccDry | cds-NP_013344.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:614706-615524:+ | gene-YLR243W_VR1 | rna-NM_001182130.1_VR1 | cds-NP_013344.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:127688-128506:+ | gene-YLR243W_ZTW1 | rna-NM_001182130.1_ZTW1 | cds-NP_013344.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:588875-589693:+ | gene-YLR243W_Sparadoxus | rna-NM_001182130.1_Sparadoxus | cds-NP_013344.1_Sparadoxus | 93.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |