Gene name: GPN2
Reference locus (S288C): YOR262W
Gene biotype: protein_coding
Description: GPN-loop GTPase 2; Putative GTPase with a role in biogenesis of RNA pol II and polIII; may be involved in assembly of RNA polymerases II and III and in their transport into the nucleus; contains a Gly-Pro-Asn motif in the G domain; similar to Npa3p and Gpn3p; highly conserved across species and homologous to human gene GPN2/ATPBD1B; required for establishment of sister chromatid cohesion
Top 10 interactors (score): NPA3 (0.995); RBA50 (0.987); RPB2 (0.952); IWR1 (0.92); FYV10 (0.888); RPO26 (0.86); RPC10 (0.847); SPC3 (0.832); RPB10 (0.826); RPB3 (0.787); CCT7 (0.746); RPB5 (0.74); CCT2 (0.732); KRS1 (0.707); O0508 (0.691); YJL009W (0.691); MVD1 (0.679); CCT8 (0.678); GPN3 (0.677); FAP7 (0.671)
Homologues (species, bitscore): GPN2 (Homo sapiens, 261.2); Gpn2 (Mus musculus, 268.5); gpn2 (Danio rerio, 266.9); gpn2 (Xenopus tropicalis, 235.3); CG10222 (Drosophila melanogaster, 238.4); B0207.6 (Caenorhabditis elegans, 186.0); QQT1 (Arabidopsis thaliana, 282.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:808067-809110:+ | gene-YOR262W_AKU4011 | rna-NM_001183681.1_AKU4011 | cds-NP_014905.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:210095-211138:+ | gene-YOR262W_BG1 | rna-NM_001183681.1_BG1 | cds-NP_014905.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:793526-794569:+ | gene-YOR262W_Bruggeman | rna-NM_001183681.1_Bruggeman | cds-NP_014905.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:794179-795222:+ | gene-YOR262W_CAT1 | rna-NM_001183681.1_CAT1 | cds-NP_014905.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:791050-792093:+ | gene-YOR262W_CBS1585 | rna-NM_001183681.1_CBS1585 | cds-NP_014905.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:789744-790787:+ | gene-YOR262W_CBS436 | rna-NM_001183681.1_CBS436 | cds-NP_014905.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:787835-788878:+ | gene-YOR262W_CBS6412 | rna-NM_001183681.1_CBS6412 | cds-NP_014905.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:796812-797855:+ | gene-YOR262W_CBS6413 | rna-NM_001183681.1_CBS6413 | cds-NP_014905.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:817053-818096:+ | gene-YOR262W_CENPK1137D | rna-NM_001183681.1_CENPK1137D | cds-NP_014905.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:784180-785223:+ | gene-YOR262W_EthanolRed | rna-NM_001183681.1_EthanolRed | cds-NP_014905.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:789579-790622:+ | gene-YOR262W_FaliES1 | rna-NM_001183681.1_FaliES1 | cds-NP_014905.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:36214-37257:- | gene-YOR262W_JAY291 | rna-NM_001183681.1_JAY291 | cds-NP_014905.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:797802-798845:+ | gene-YOR262W_MUCL30387 | rna-NM_001183681.1_MUCL30387 | cds-NP_014905.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:804918-805961:+ | gene-YOR262W_MUCL30388 | rna-NM_001183681.1_MUCL30388 | cds-NP_014905.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:798384-799427:+ | gene-YOR262W_MUCL39482 | rna-NM_001183681.1_MUCL39482 | cds-NP_014905.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:807971-809014:+ | gene-YOR262W_MUCL42920 | rna-NM_001183681.1_MUCL42920 | cds-NP_014905.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:817181-818224:+ | gene-YOR262W_NCIM3186 | rna-NM_001183681.1_NCIM3186 | cds-NP_014905.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:798479-799522:+ | gene-YOR262W_NCYC1407 | rna-NM_001183681.1_NCYC1407 | cds-NP_014905.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:797777-798820:+ | gene-YOR262W_PE2H3 | rna-NM_001183681.1_PE2H3 | cds-NP_014905.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:808154-809197:+ | gene-YOR262W_PE2H4 | rna-NM_001183681.1_PE2H4 | cds-NP_014905.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:817292-818335:+ | gene-YOR262W_S288C | rna-NM_001183681.1_S288C | cds-NP_014905.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:227282-228325:+ | gene-YOR262W_SA1 | rna-NM_001183681.1_SA1 | cds-NP_014905.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:788762-789805:+ | gene-YOR262W_ThermosaccDry | rna-NM_001183681.1_ThermosaccDry | cds-NP_014905.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:852217-853260:+ | gene-YOR262W_VR1 | rna-NM_001183681.1_VR1 | cds-NP_014905.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:521683-522726:+ | gene-YOR262W_ZTW1 | rna-NM_001183681.1_ZTW1 | cds-NP_014905.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:794543-795586:+ | gene-YOR262W_Sparadoxus | rna-NM_001183681.1_Sparadoxus | cds-NP_014905.1_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |