Gene name: GPI12
Reference locus (S288C): YMR281W
Gene biotype: protein_coding
Description: N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; ER membrane protein involved in the second step of GPI anchor assembly; the second step is the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate; functional homolog of human PIG-Lp; GPI stands for glycosylphosphatidylinositol; Belongs to the PIGL family
Top 10 interactors (score): GPI1 (0.996); SPT14 (0.994); GPI19 (0.994); GPI2 (0.993); GPI18 (0.984); GPI14 (0.984); GPI15 (0.982); GPI10 (0.973); ERI1 (0.968); GWT1 (0.968); LAS21 (0.943); GAA1 (0.927); GPI13 (0.925); GPI16 (0.909); GPI8 (0.908); YJL132W (0.9); GPI11 (0.882); MCD4 (0.872); CWH43 (0.814); GPI17 (0.76)
Homologues (species, bitscore): PIGL (Homo sapiens, 97.8); Pigl (Mus musculus, 102.1); pigl (Danio rerio, 78.2); PIG-L (Drosophila melanogaster, 61.6); Y52B11C.1 (Caenorhabditis elegans, 97.1); AT2G27340 (Arabidopsis thaliana, 101.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:871390-872304:+ | gene-YMR281W_AKU4011 | rna-NM_001182788.1_AKU4011 | cds-NP_014008.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:81368-82282:- | gene-YMR281W_BG1 | rna-NM_001182788.1_BG1 | cds-NP_014008.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:816600-817514:+ | gene-YMR281W_Bruggeman | rna-NM_001182788.1_Bruggeman | cds-NP_014008.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:819885-820799:+ | gene-YMR281W_CAT1 | rna-NM_001182788.1_CAT1 | cds-NP_014008.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:803640-804554:+ | gene-YMR281W_CBS1585 | rna-NM_001182788.1_CBS1585 | cds-NP_014008.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:825956-826870:+ | gene-YMR281W_CBS436 | rna-NM_001182788.1_CBS436 | cds-NP_014008.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:915214-916128:+ | gene-YMR281W_CBS6412 | rna-NM_001182788.1_CBS6412 | cds-NP_014008.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:802761-803675:+ | gene-YMR281W_CBS6413 | rna-NM_001182788.1_CBS6413 | cds-NP_014008.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:826885-827799:+ | gene-YMR281W_CENPK1137D | rna-NM_001182788.1_CENPK1137D | cds-NP_014008.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:864080-864994:+ | gene-YMR281W_EthanolRed | rna-NM_001182788.1_EthanolRed | cds-NP_014008.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:810107-811021:+ | gene-YMR281W_FaliES1 | rna-NM_001182788.1_FaliES1 | cds-NP_014008.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000262.1:40711-41625:- | gene-YMR281W_JAY291 | rna-NM_001182788.1_JAY291 | cds-NP_014008.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:810425-811339:+ | gene-YMR281W_MUCL30387 | rna-NM_001182788.1_MUCL30387 | cds-NP_014008.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:819822-820736:+ | gene-YMR281W_MUCL30388 | rna-NM_001182788.1_MUCL30388 | cds-NP_014008.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:804728-805642:+ | gene-YMR281W_MUCL39482 | rna-NM_001182788.1_MUCL39482 | cds-NP_014008.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:813533-814447:+ | gene-YMR281W_MUCL42920 | rna-NM_001182788.1_MUCL42920 | cds-NP_014008.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:832293-833207:+ | gene-YMR281W_NCIM3186 | rna-NM_001182788.1_NCIM3186 | cds-NP_014008.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:804371-805285:+ | gene-YMR281W_NCYC1407 | rna-NM_001182788.1_NCYC1407 | cds-NP_014008.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:820177-821091:+ | gene-YMR281W_PE2H3 | rna-NM_001182788.1_PE2H3 | cds-NP_014008.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:816151-817065:+ | gene-YMR281W_PE2H4 | rna-NM_001182788.1_PE2H4 | cds-NP_014008.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:832339-833253:+ | gene-YMR281W_S288C | rna-NM_001182788.1_S288C | cds-NP_014008.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000036.1:9762-10676:+ | gene-YMR281W_SA1 | rna-NM_001182788.1_SA1 | cds-NP_014008.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:806276-807190:+ | gene-YMR281W_ThermosaccDry | rna-NM_001182788.1_ThermosaccDry | cds-NP_014008.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:819524-820438:+ | gene-YMR281W_VR1 | rna-NM_001182788.1_VR1 | cds-NP_014008.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:221510-222424:+ | gene-YMR281W_ZTW1 | rna-NM_001182788.1_ZTW1 | cds-NP_014008.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:824726-825640:+ | gene-YMR281W_Sparadoxus | rna-NM_001182788.1_Sparadoxus | cds-NP_014008.1_Sparadoxus | 87.2 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |