GPD2 (YOL059W)


Gene profile

Gene name: GPD2
Reference locus (S288C): YOL059W
Gene biotype: protein_coding

Description: Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, mitochondrial; NAD-dependent glycerol 3-phosphate dehydrogenase; expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions; located in cytosol and mitochondria; constitutively active but is inactivated via phosphorylation by energy-stress responsive kinase SNF1; GPD2 has a paralog, GPD1, that arose from the whole genome duplication

Top 10 interactors (score): GPD1 (0.982); DAK1 (0.971); GUT2 (0.971); GPP2 (0.97); GPP1 (0.967); DAK2 (0.943); GPT2 (0.923); SCT1 (0.923); PAH1 (0.858); LPP1 (0.808); DPP1 (0.808); BAT1 (0.774); FMO1 (0.749); GUT1 (0.749); SLC1 (0.743); TPI1 (0.735); ALE1 (0.674); FBP26 (0.67); PUF3 (0.669); RIM11 (0.651)

Homologues (species, bitscore): GPD1 (Homo sapiens, 312.4); Gpd1 (Mus musculus, 320.5); gpd1b (Danio rerio, 310.8); gpd1 (Xenopus tropicalis, 304.7); Gpdh (Drosophila melanogaster, 297.0); gpdh-2 (Caenorhabditis elegans, 311.2); GPDHp (Arabidopsis thaliana, 300.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:200807-202129:+ gene-YOL059W_AKU4011 rna-NM_001183314.1_AKU4011 cds-NP_014582.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:16677-17999:+ gene-YOL059W_BG1 rna-NM_001183314.1_BG1 cds-NP_014582.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:202476-203798:+ gene-YOL059W_Bruggeman rna-NM_001183314.1_Bruggeman cds-NP_014582.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:201990-203312:+ gene-YOL059W_CAT1 rna-NM_001183314.1_CAT1 cds-NP_014582.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:195198-196520:+ gene-YOL059W_CBS1585 rna-NM_001183314.1_CBS1585 cds-NP_014582.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:200357-201679:+ gene-YOL059W_CBS436 rna-NM_001183314.1_CBS436 cds-NP_014582.1_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:195127-196449:+ gene-YOL059W_CBS6412 rna-NM_001183314.1_CBS6412 cds-NP_014582.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:202063-203385:+ gene-YOL059W_CBS6413 rna-NM_001183314.1_CBS6413 cds-NP_014582.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:216829-218151:+ gene-YOL059W_CENPK1137D rna-NM_001183314.1_CENPK1137D cds-NP_014582.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:197905-199227:+ gene-YOL059W_EthanolRed rna-NM_001183314.1_EthanolRed cds-NP_014582.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:200449-201771:+ gene-YOL059W_FaliES1 rna-NM_001183314.1_FaliES1 cds-NP_014582.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000018.1:63786-65108:- gene-YOL059W_JAY291 rna-NM_001183314.1_JAY291 cds-NP_014582.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:206244-207566:+ gene-YOL059W_MUCL30387 rna-NM_001183314.1_MUCL30387 cds-NP_014582.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:210540-211862:+ gene-YOL059W_MUCL30388 rna-NM_001183314.1_MUCL30388 cds-NP_014582.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:203118-204440:+ gene-YOL059W_MUCL39482 rna-NM_001183314.1_MUCL39482 cds-NP_014582.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:218597-219919:+ gene-YOL059W_MUCL42920 rna-NM_001183314.1_MUCL42920 cds-NP_014582.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:217015-218337:+ gene-YOL059W_NCIM3186 rna-NM_001183314.1_NCIM3186 cds-NP_014582.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:209735-211057:+ gene-YOL059W_NCYC1407 rna-NM_001183314.1_NCYC1407 cds-NP_014582.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:192740-194062:+ gene-YOL059W_PE2H3 rna-NM_001183314.1_PE2H3 cds-NP_014582.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:203732-205054:+ gene-YOL059W_PE2H4 rna-NM_001183314.1_PE2H4 cds-NP_014582.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:217126-218448:+ gene-YOL059W_S288C rna-NM_001183314.1_S288C cds-NP_014582.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:185090-186412:+ gene-YOL059W_SA1 rna-NM_001183314.1_SA1 cds-NP_014582.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:199457-200779:+ gene-YOL059W_ThermosaccDry rna-NM_001183314.1_ThermosaccDry cds-NP_014582.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:200189-201511:+ gene-YOL059W_VR1 rna-NM_001183314.1_VR1 cds-NP_014582.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000031.1:199097-200419:+ gene-YOL059W_ZTW1 rna-NM_001183314.1_ZTW1 cds-NP_014582.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:202605-203927:+ gene-YOL059W_Sparadoxus rna-NM_001183314.1_Sparadoxus cds-NP_014582.1_Sparadoxus 94.3 100.0 Unannotated 1 1 0 False False False False True

Additional files