Gene name: GPB2
Reference locus (S288C): YAL056W
Gene biotype: protein_coding
Description: Guanine nucleotide-binding protein subunit beta 2; Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole genome duplication
Top 10 interactors (score): GPA2 (0.995); IRA2 (0.935); IRA1 (0.922); GPR1 (0.91); CYR1 (0.834); BCY1 (0.822); PDE2 (0.81); GPB1 (0.804); GPG1 (0.771); TPK1 (0.769); MXR2 (0.768); RAS2 (0.746); DSE4 (0.733); PDE1 (0.714); RPS22B (0.707); RGS2 (0.699); TPK2 (0.663); PEX34 (0.661); RIM15 (0.655); TPK3 (0.629)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:24407-27049:+ | gene-YAL056W_AKU4011 | rna-NM_001178199.2_AKU4011 | cds-NP_009345.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:11471-14113:+ | gene-YAL056W_BG1 | rna-NM_001178199.2_BG1 | cds-NP_009345.3_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:38612-41254:+ | gene-YAL056W_Bruggeman | rna-NM_001178199.2_Bruggeman | cds-NP_009345.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:25122-27764:+ | gene-YAL056W_CAT1 | rna-NM_001178199.2_CAT1 | cds-NP_009345.3_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:37427-40069:+ | gene-YAL056W_CBS1585 | rna-NM_001178199.2_CBS1585 | cds-NP_009345.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:37667-40309:+ | gene-YAL056W_CBS436 | rna-NM_001178199.2_CBS436 | cds-NP_009345.3_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:23570-26212:+ | gene-YAL056W_CBS6412 | rna-NM_001178199.2_CBS6412 | cds-NP_009345.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:35691-38333:+ | gene-YAL056W_CBS6413 | rna-NM_001178199.2_CBS6413 | cds-NP_009345.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:39315-41957:+ | gene-YAL056W_CENPK1137D | rna-NM_001178199.2_CENPK1137D | cds-NP_009345.3_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:25820-28462:+ | gene-YAL056W_EthanolRed | rna-NM_001178199.2_EthanolRed | cds-NP_009345.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:39763-42405:+ | gene-YAL056W_FaliES1 | rna-NM_001178199.2_FaliES1 | cds-NP_009345.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:11709-14351:+ | gene-YAL056W_JAY291 | rna-NM_001178199.2_JAY291 | cds-NP_009345.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:40366-43008:+ | gene-YAL056W_MUCL30387 | rna-NM_001178199.2_MUCL30387 | cds-NP_009345.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:36909-39551:+ | gene-YAL056W_MUCL30388 | rna-NM_001178199.2_MUCL30388 | cds-NP_009345.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:36230-38872:+ | gene-YAL056W_MUCL39482 | rna-NM_001178199.2_MUCL39482 | cds-NP_009345.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:38569-41211:+ | gene-YAL056W_MUCL42920 | rna-NM_001178199.2_MUCL42920 | cds-NP_009345.3_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:39136-41778:+ | gene-YAL056W_NCIM3186 | rna-NM_001178199.2_NCIM3186 | cds-NP_009345.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:24093-26735:+ | gene-YAL056W_NCYC1407 | rna-NM_001178199.2_NCYC1407 | cds-NP_009345.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:25971-28613:+ | gene-YAL056W_PE2H3 | rna-NM_001178199.2_PE2H3 | cds-NP_009345.3_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:25692-28334:+ | gene-YAL056W_PE2H4 | rna-NM_001178199.2_PE2H4 | cds-NP_009345.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:39259-41901:+ | gene-YAL056W_S288C | rna-NM_001178199.2_S288C | cds-NP_009345.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000084.1:13865-16507:+ | gene-YAL056W_SA1 | rna-NM_001178199.2_SA1 | cds-NP_009345.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:39972-42614:+ | gene-YAL056W_ThermosaccDry | rna-NM_001178199.2_ThermosaccDry | cds-NP_009345.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:40726-43368:+ | gene-YAL056W_VR1 | rna-NM_001178199.2_VR1 | cds-NP_009345.3_VR1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:11779-14421:+ | gene-YAL056W_ZTW1 | rna-NM_001178199.2_ZTW1 | cds-NP_009345.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:29481-32141:+ | gene-YAL056W_Sparadoxus | rna-NM_001178199.2_Sparadoxus | cds-NP_009345.3_Sparadoxus | 87.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |