Gene name: GPB1
Reference locus (S288C): YOR371C
Gene biotype: protein_coding
Description: Guanine nucleotide-binding protein subunit beta 1; Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; promotes ubiquitin-dependent proteolysis of Ira2p; regulated by G-alpha protein Gpa2p; GPB1 has a paralog, GPB2, that arose from the whole genome duplication
Top 10 interactors (score): GPA2 (0.984); IRA2 (0.945); GPG1 (0.943); GPR1 (0.91); IRA1 (0.893); CYR1 (0.861); BCY1 (0.825); PDE2 (0.816); GPB2 (0.804); RAS2 (0.79); PDE1 (0.76); RGS2 (0.749); GPA1 (0.712); TPK2 (0.71); TPK1 (0.706); CPR2 (0.671); TPK3 (0.617); ASC1 (0.597); CDC25 (0.572); SFL1 (0.572)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:1018091-1020784:- | gene-YOR371C_AKU4011 | rna-NM_001183791.3_AKU4011 | cds-NP_015016.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000183.1:40715-43408:+ | gene-YOR371C_BG1 | rna-NM_001183791.3_BG1 | cds-NP_015016.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:1002898-1005591:- | gene-YOR371C_Bruggeman | rna-NM_001183791.3_Bruggeman | cds-NP_015016.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:1003554-1006247:- | gene-YOR371C_CAT1 | rna-NM_001183791.3_CAT1 | cds-NP_015016.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:1002501-1005194:- | gene-YOR371C_CBS1585 | rna-NM_001183791.3_CBS1585 | cds-NP_015016.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:997304-999994:- | gene-YOR371C_CBS436 | rna-NM_001183791.3_CBS436 | cds-NP_015016.3_CBS436 | 99.8 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:231794-234487:- | gene-YOR371C_CBS6412 | rna-NM_001183791.3_CBS6412 | cds-NP_015016.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:1006775-1009468:- | gene-YOR371C_CBS6413 | rna-NM_001183791.3_CBS6413 | cds-NP_015016.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:1031345-1034038:- | gene-YOR371C_CENPK1137D | rna-NM_001183791.3_CENPK1137D | cds-NP_015016.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:246826-249519:- | gene-YOR371C_EthanolRed | rna-NM_001183791.3_EthanolRed | cds-NP_015016.3_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:999626-1002319:- | gene-YOR371C_FaliES1 | rna-NM_001183791.3_FaliES1 | cds-NP_015016.3_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:3346-6039:+ | gene-YOR371C_JAY291 | rna-NM_001183791.3_JAY291 | cds-NP_015016.3_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:1012232-1014925:- | gene-YOR371C_MUCL30387 | rna-NM_001183791.3_MUCL30387 | cds-NP_015016.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:1020252-1022945:- | gene-YOR371C_MUCL30388 | rna-NM_001183791.3_MUCL30388 | cds-NP_015016.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:1009021-1011714:- | gene-YOR371C_MUCL39482 | rna-NM_001183791.3_MUCL39482 | cds-NP_015016.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:1016647-1019340:- | gene-YOR371C_MUCL42920 | rna-NM_001183791.3_MUCL42920 | cds-NP_015016.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:1031378-1034071:- | gene-YOR371C_NCIM3186 | rna-NM_001183791.3_NCIM3186 | cds-NP_015016.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:1010042-1012735:- | gene-YOR371C_NCYC1407 | rna-NM_001183791.3_NCYC1407 | cds-NP_015016.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:1005310-1008003:- | gene-YOR371C_PE2H3 | rna-NM_001183791.3_PE2H3 | cds-NP_015016.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:1021661-1024354:- | gene-YOR371C_PE2H4 | rna-NM_001183791.3_PE2H4 | cds-NP_015016.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:1031489-1034182:- | gene-YOR371C_S288C | rna-NM_001183791.3_S288C | cds-NP_015016.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:136099-138792:- | gene-YOR371C_SA1 | rna-NM_001183791.3_SA1 | cds-NP_015016.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:998808-1001501:- | gene-YOR371C_ThermosaccDry | rna-NM_001183791.3_ThermosaccDry | cds-NP_015016.3_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:1060291-1062984:- | gene-YOR371C_VR1 | rna-NM_001183791.3_VR1 | cds-NP_015016.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:731533-734226:- | gene-YOR371C_ZTW1 | rna-NM_001183791.3_ZTW1 | cds-NP_015016.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:1005578-1008268:- | gene-YOR371C_Sparadoxus | rna-NM_001183791.3_Sparadoxus | cds-NP_015016.3_Sparadoxus | 89.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |