Gene name: GPA2
Reference locus (S288C): YER020W
Gene biotype: protein_coding
Description: Guanine nucleotide-binding protein alpha-2 subunit; Nucleotide binding alpha subunit of the heterotrimeric G protein; interacts with the receptor Gpr1p, has signaling role in response to nutrients; required for the recruitment of Ras-GTP at the plasma membrane and in the nucleus
Top 10 interactors (score): GPR1 (0.999); CYR1 (0.999); STE4 (0.999); GPB2 (0.995); RAS2 (0.994); RGS2 (0.987); GPB1 (0.984); CDC42 (0.982); SST2 (0.974); RAS1 (0.974); BCY1 (0.967); PDE2 (0.966); TPK2 (0.965); DAL1 (0.961); HOG1 (0.96); TPK1 (0.954); SLT2 (0.948); SMK1 (0.941); PDE1 (0.935); TPK3 (0.935)
Homologues (species, bitscore): GNAI1 (Homo sapiens, 293.1); Gnai2 (Mus musculus, 293.1); gnai2b (Danio rerio, 291.2); gnai3 (Xenopus tropicalis, 286.6); Galphao (Drosophila melanogaster, 285.0); goa-1 (Caenorhabditis elegans, 284.6); GPA1 (Arabidopsis thaliana, 209.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:189202-190551:+ | gene-YER020W_AKU4011 | rna-NM_001178911.3_AKU4011 | cds-NP_010937.3_AKU4011 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:235540-236889:- | gene-YER020W_BG1 | rna-NM_001178911.3_BG1 | cds-NP_010937.3_BG1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:197058-198407:+ | gene-YER020W_Bruggeman | rna-NM_001178911.3_Bruggeman | cds-NP_010937.3_Bruggeman | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:191948-193297:+ | gene-YER020W_CAT1 | rna-NM_001178911.3_CAT1 | cds-NP_010937.3_CAT1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:189125-190474:+ | gene-YER020W_CBS1585 | rna-NM_001178911.3_CBS1585 | cds-NP_010937.3_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:190711-192060:+ | gene-YER020W_CBS436 | rna-NM_001178911.3_CBS436 | cds-NP_010937.3_CBS436 | 98.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:189369-190718:+ | gene-YER020W_CBS6412 | rna-NM_001178911.3_CBS6412 | cds-NP_010937.3_CBS6412 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:194155-195504:+ | gene-YER020W_CBS6413 | rna-NM_001178911.3_CBS6413 | cds-NP_010937.3_CBS6413 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:193057-194440:+ | gene-YER020W_CENPK1137D | rna-NM_001178911.3_CENPK1137D | cds-NP_010937.3_CENPK1137D | 94.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:189829-191178:+ | gene-YER020W_EthanolRed | rna-NM_001178911.3_EthanolRed | cds-NP_010937.3_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:190088-191437:+ | gene-YER020W_FaliES1 | rna-NM_001178911.3_FaliES1 | cds-NP_010937.3_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000024.1:56711-58060:+ | gene-YER020W_JAY291 | rna-NM_001178911.3_JAY291 | cds-NP_010937.3_JAY291 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:193269-194618:+ | gene-YER020W_MUCL30387 | rna-NM_001178911.3_MUCL30387 | cds-NP_010937.3_MUCL30387 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:189504-190853:+ | gene-YER020W_MUCL30388 | rna-NM_001178911.3_MUCL30388 | cds-NP_010937.3_MUCL30388 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:188168-189517:+ | gene-YER020W_MUCL39482 | rna-NM_001178911.3_MUCL39482 | cds-NP_010937.3_MUCL39482 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:195255-196604:+ | gene-YER020W_MUCL42920 | rna-NM_001178911.3_MUCL42920 | cds-NP_010937.3_MUCL42920 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:195167-196516:+ | gene-YER020W_NCIM3186 | rna-NM_001178911.3_NCIM3186 | cds-NP_010937.3_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:193240-194589:+ | gene-YER020W_NCYC1407 | rna-NM_001178911.3_NCYC1407 | cds-NP_010937.3_NCYC1407 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:197553-198902:+ | gene-YER020W_PE2H3 | rna-NM_001178911.3_PE2H3 | cds-NP_010937.3_PE2H3 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:193452-194801:+ | gene-YER020W_PE2H4 | rna-NM_001178911.3_PE2H4 | cds-NP_010937.3_PE2H4 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:195168-196517:+ | gene-YER020W_S288C | rna-NM_001178911.3_S288C | cds-NP_010937.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000020.1:47169-48518:- | gene-YER020W_SA1 | rna-NM_001178911.3_SA1 | cds-NP_010937.3_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:190859-192208:+ | gene-YER020W_ThermosaccDry | rna-NM_001178911.3_ThermosaccDry | cds-NP_010937.3_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:189612-190961:+ | gene-YER020W_VR1 | rna-NM_001178911.3_VR1 | cds-NP_010937.3_VR1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:188071-189420:+ | gene-YER020W_ZTW1 | rna-NM_001178911.3_ZTW1 | cds-NP_010937.3_ZTW1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:191814-193169:+ | gene-YER020W_Sparadoxus | rna-NM_001178911.3_Sparadoxus | cds-NP_010937.3_Sparadoxus | 89.0 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |