GNP1 (YDR508C)


Gene profile

Gene name: GNP1
Reference locus (S288C): YDR508C
Gene biotype: protein_coding

Description: High-affinity glutamine permease; also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids; GNP1 has a paralog, AGP1, that arose from the whole genome duplication

Top 10 interactors (score): AGP1 (0.999); MUP1 (0.741); PTR2 (0.717); PTR3 (0.711); SSY5 (0.69); CCL1 (0.688); KAR2 (0.683); MEP1 (0.667); AVT5 (0.64); BUL1 (0.605); YBR287W (0.602); MEP3 (0.58); MEP2 (0.576); SSY1 (0.57); YCT1 (0.544); STP2 (0.526); STP1 (0.526); BAP3 (0.51); FCY2 (0.5); SHR3 (0.5)

Homologues (species, bitscore): SLC7A8 (Homo sapiens, 54.3); Slc7a5 (Mus musculus, 56.6); slc7a8a (Danio rerio, 60.5); slc7a5 (Xenopus tropicalis, 65.1); CG7255 (Drosophila melanogaster, 52.0); aat-1 (Caenorhabditis elegans, 61.6); At5g36940 (Arabidopsis thaliana, 53.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1406462-1408453:- gene-YDR508C_AKU4011 rna-NM_001180816.1_AKU4011 cds-NP_010796.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000073.1:48116-50107:- gene-YDR508C_BG1 rna-NM_001180816.1_BG1 cds-NP_010796.1_BG1 98.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1437781-1439772:- gene-YDR508C_Bruggeman rna-NM_001180816.1_Bruggeman cds-NP_010796.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1414956-1416947:- gene-YDR508C_CAT1 rna-NM_001180816.1_CAT1 cds-NP_010796.1_CAT1 98.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1401197-1403188:- gene-YDR508C_CBS1585 rna-NM_001180816.1_CBS1585 cds-NP_010796.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1420426-1422417:- gene-YDR508C_CBS436 rna-NM_001180816.1_CBS436 cds-NP_010796.1_CBS436 98.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1396347-1398338:- gene-YDR508C_CBS6412 rna-NM_001180816.1_CBS6412 cds-NP_010796.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1419851-1421842:- gene-YDR508C_CBS6413 rna-NM_001180816.1_CBS6413 cds-NP_010796.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1465146-1467137:- gene-YDR508C_CENPK1137D rna-NM_001180816.1_CENPK1137D cds-NP_010796.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1409730-1411721:- gene-YDR508C_EthanolRed rna-NM_001180816.1_EthanolRed cds-NP_010796.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1413282-1415273:- gene-YDR508C_FaliES1 rna-NM_001180816.1_FaliES1 cds-NP_010796.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:111659-113650:- gene-YDR508C_JAY291 rna-NM_001180816.1_JAY291 cds-NP_010796.1_JAY291 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1420871-1422862:- gene-YDR508C_MUCL30387 rna-NM_001180816.1_MUCL30387 cds-NP_010796.1_MUCL30387 98.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1402304-1404295:- gene-YDR508C_MUCL30388 rna-NM_001180816.1_MUCL30388 cds-NP_010796.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1392686-1394677:- gene-YDR508C_MUCL39482 rna-NM_001180816.1_MUCL39482 cds-NP_010796.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1335348-1337339:- gene-YDR508C_MUCL42920 rna-NM_001180816.1_MUCL42920 cds-NP_010796.1_MUCL42920 98.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1466376-1468367:- gene-YDR508C_NCIM3186 rna-NM_001180816.1_NCIM3186 cds-NP_010796.1_NCIM3186 98.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1405976-1407967:- gene-YDR508C_NCYC1407 rna-NM_001180816.1_NCYC1407 cds-NP_010796.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1416926-1418917:- gene-YDR508C_PE2H3 rna-NM_001180816.1_PE2H3 cds-NP_010796.1_PE2H3 98.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1422392-1424383:- gene-YDR508C_PE2H4 rna-NM_001180816.1_PE2H4 cds-NP_010796.1_PE2H4 98.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1466453-1468444:- gene-YDR508C_S288C rna-NM_001180816.1_S288C cds-NP_010796.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:148671-150662:+ gene-YDR508C_SA1 rna-NM_001180816.1_SA1 cds-NP_010796.1_SA1 98.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1417504-1419495:- gene-YDR508C_ThermosaccDry rna-NM_001180816.1_ThermosaccDry cds-NP_010796.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1433297-1435288:- gene-YDR508C_VR1 rna-NM_001180816.1_VR1 cds-NP_010796.1_VR1 98.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:460165-462156:- gene-YDR508C_ZTW1 rna-NM_001180816.1_ZTW1 cds-NP_010796.1_ZTW1 98.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1426399-1428390:- gene-YDR508C_Sparadoxus rna-NM_001180816.1_Sparadoxus cds-NP_010796.1_Sparadoxus 91.0 99.8 Verified 1 1 1 False True False False False

Additional files