GND2 (YGR256W)


Gene profile

Gene name: GND2
Reference locus (S288C): YGR256W
Gene biotype: protein_coding

Description: 6-phosphogluconate dehydrogenase (decarboxylating); catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone; GND2 has a paralog, GND1, that arose from the whole genome duplication

Top 10 interactors (score): ZWF1 (0.999); RPE1 (0.998); NQM1 (0.998); TKL2 (0.997); SOL4 (0.996); YDR248C (0.994); SOL3 (0.99); GND1 (0.983); TAL1 (0.979); PGK1 (0.979); ALD3 (0.977); RKI1 (0.971); SOL1 (0.969); SOL2 (0.961); TKL1 (0.959); GRE1 (0.93); HXT5 (0.926); HBT1 (0.923); CTT1 (0.915); YBR116C (0.913)

Homologues (species, bitscore): PGD (Homo sapiens, 651.7); Pgd (Mus musculus, 655.6); pgd (Danio rerio, 647.5); pgd (Xenopus tropicalis, 566.6); Pgd (Drosophila melanogaster, 642.1); T25B9.9 (Caenorhabditis elegans, 650.6); AT5G41670 (Arabidopsis thaliana, 461.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:970063-971541:+ gene-YGR256W_AKU4011 rna-NM_001181385.3_AKU4011 cds-NP_011772.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:250224-251702:+ gene-YGR256W_BG1 rna-NM_001181385.3_BG1 cds-NP_011772.3_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:978574-980052:+ gene-YGR256W_Bruggeman rna-NM_001181385.3_Bruggeman cds-NP_011772.3_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:977517-978995:+ gene-YGR256W_CAT1 rna-NM_001181385.3_CAT1 cds-NP_011772.3_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:972933-974411:+ gene-YGR256W_CBS1585 rna-NM_001181385.3_CBS1585 cds-NP_011772.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:976554-978032:+ gene-YGR256W_CBS436 rna-NM_001181385.3_CBS436 cds-NP_011772.3_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:963823-965301:+ gene-YGR256W_CBS6412 rna-NM_001181385.3_CBS6412 cds-NP_011772.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:969878-971356:+ gene-YGR256W_CBS6413 rna-NM_001181385.3_CBS6413 cds-NP_011772.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:1004305-1005783:+ gene-YGR256W_CENPK1137D rna-NM_001181385.3_CENPK1137D cds-NP_011772.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:957906-959384:+ gene-YGR256W_EthanolRed rna-NM_001181385.3_EthanolRed cds-NP_011772.3_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:962712-964190:+ gene-YGR256W_FaliES1 rna-NM_001181385.3_FaliES1 cds-NP_011772.3_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000076.1:66122-67600:- gene-YGR256W_JAY291 rna-NM_001181385.3_JAY291 cds-NP_011772.3_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:976315-977793:+ gene-YGR256W_MUCL30387 rna-NM_001181385.3_MUCL30387 cds-NP_011772.3_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:974449-975927:+ gene-YGR256W_MUCL30388 rna-NM_001181385.3_MUCL30388 cds-NP_011772.3_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:968039-969517:+ gene-YGR256W_MUCL39482 rna-NM_001181385.3_MUCL39482 cds-NP_011772.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:985903-987381:+ gene-YGR256W_MUCL42920 rna-NM_001181385.3_MUCL42920 cds-NP_011772.3_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:1004624-1006102:+ gene-YGR256W_NCIM3186 rna-NM_001181385.3_NCIM3186 cds-NP_011772.3_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:963668-965146:+ gene-YGR256W_NCYC1407 rna-NM_001181385.3_NCYC1407 cds-NP_011772.3_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:988847-990325:+ gene-YGR256W_PE2H3 rna-NM_001181385.3_PE2H3 cds-NP_011772.3_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:993686-995164:+ gene-YGR256W_PE2H4 rna-NM_001181385.3_PE2H4 cds-NP_011772.3_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:1004624-1006102:+ gene-YGR256W_S288C rna-NM_001181385.3_S288C cds-NP_011772.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000063.1:2844-4322:+ gene-YGR256W_SA1 rna-NM_001181385.3_SA1 cds-NP_011772.3_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:983232-984710:+ gene-YGR256W_ThermosaccDry rna-NM_001181385.3_ThermosaccDry cds-NP_011772.3_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:1089010-1090488:+ gene-YGR256W_VR1 rna-NM_001181385.3_VR1 cds-NP_011772.3_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:284652-286130:+ gene-YGR256W_ZTW1 rna-NM_001181385.3_ZTW1 cds-NP_011772.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:975205-976683:+ gene-YGR256W_Sparadoxus rna-NM_001181385.3_Sparadoxus cds-NP_011772.3_Sparadoxus 91.0 100.0 Verified 1 1 1 False True False False False

Additional files