GND1 (YHR183W)


Gene profile

Gene name: GND1
Reference locus (S288C): YHR183W
Gene biotype: protein_coding

Description: 6-phosphogluconate dehydrogenase (decarboxylating); catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress; GND1 has a paralog, GND2, that arose from the whole genome duplication

Top 10 interactors (score): RPE1 (0.999); ZWF1 (0.999); SOL3 (0.996); YDR248C (0.994); TKL1 (0.992); SOL4 (0.99); TAL1 (0.988); GND2 (0.983); PGK1 (0.983); SOL1 (0.979); RKI1 (0.973); NQM1 (0.97); SOL2 (0.954); TKL2 (0.947); PGI1 (0.923); GLR1 (0.873); TRR2 (0.817); TRR1 (0.816); ALD6 (0.794); GDH1 (0.789)

Homologues (species, bitscore): PGD (Homo sapiens, 664.1); Pgd (Mus musculus, 668.3); pgd (Danio rerio, 657.5); pgd (Xenopus tropicalis, 572.8); Pgd (Drosophila melanogaster, 659.4); T25B9.9 (Caenorhabditis elegans, 649.4); AT5G41670 (Arabidopsis thaliana, 464.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:458048-459517:+ gene-YHR183W_AKU4011 rna-NM_001179314.3_AKU4011 cds-NP_012053.3_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000141.1:58233-59702:- gene-YHR183W_BG1 rna-NM_001179314.3_BG1 cds-NP_012053.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:465297-466766:+ gene-YHR183W_Bruggeman rna-NM_001179314.3_Bruggeman cds-NP_012053.3_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:461561-463030:+ gene-YHR183W_CAT1 rna-NM_001179314.3_CAT1 cds-NP_012053.3_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:457500-458969:+ gene-YHR183W_CBS1585 rna-NM_001179314.3_CBS1585 cds-NP_012053.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:454949-456418:+ gene-YHR183W_CBS436 rna-NM_001179314.3_CBS436 cds-NP_012053.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:457599-459068:+ gene-YHR183W_CBS6412 rna-NM_001179314.3_CBS6412 cds-NP_012053.3_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:458890-460359:+ gene-YHR183W_CBS6413 rna-NM_001179314.3_CBS6413 cds-NP_012053.3_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:464148-465617:+ gene-YHR183W_CENPK1137D rna-NM_001179314.3_CENPK1137D cds-NP_012053.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:516593-518062:+ gene-YHR183W_EthanolRed rna-NM_001179314.3_EthanolRed cds-NP_012053.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:459037-460506:+ gene-YHR183W_FaliES1 rna-NM_001179314.3_FaliES1 cds-NP_012053.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000147.1:4187-5656:+ gene-YHR183W_JAY291 rna-NM_001179314.3_JAY291 cds-NP_012053.3_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:466623-468092:+ gene-YHR183W_MUCL30387 rna-NM_001179314.3_MUCL30387 cds-NP_012053.3_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:466046-467515:+ gene-YHR183W_MUCL30388 rna-NM_001179314.3_MUCL30388 cds-NP_012053.3_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:457411-458880:+ gene-YHR183W_MUCL39482 rna-NM_001179314.3_MUCL39482 cds-NP_012053.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:465353-466822:+ gene-YHR183W_MUCL42920 rna-NM_001179314.3_MUCL42920 cds-NP_012053.3_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:470842-472311:+ gene-YHR183W_NCIM3186 rna-NM_001179314.3_NCIM3186 cds-NP_012053.3_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:459872-461341:+ gene-YHR183W_NCYC1407 rna-NM_001179314.3_NCYC1407 cds-NP_012053.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:459025-460494:+ gene-YHR183W_PE2H3 rna-NM_001179314.3_PE2H3 cds-NP_012053.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:466452-467921:+ gene-YHR183W_PE2H4 rna-NM_001179314.3_PE2H4 cds-NP_012053.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:470960-472429:+ gene-YHR183W_S288C rna-NM_001179314.3_S288C cds-NP_012053.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000079.1:19116-20585:+ gene-YHR183W_SA1 rna-NM_001179314.3_SA1 cds-NP_012053.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:460120-461589:+ gene-YHR183W_ThermosaccDry rna-NM_001179314.3_ThermosaccDry cds-NP_012053.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:469326-470795:+ gene-YHR183W_VR1 rna-NM_001179314.3_VR1 cds-NP_012053.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:450358-451827:+ gene-YHR183W_ZTW1 rna-NM_001179314.3_ZTW1 cds-NP_012053.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:457050-458519:+ gene-YHR183W_Sparadoxus rna-NM_001179314.3_Sparadoxus cds-NP_012053.3_Sparadoxus 96.3 100.0 Verified 1 1 1 False True False False False

Additional files