GMC2 (YLR445W)


Gene profile

Gene name: GMC2
Reference locus (S288C): YLR445W
Gene biotype: protein_coding

Description: Grand meiotic recombination cluster protein 2; Protein involved in meiotic crossing over; component of the Synaptonemal Complex (SC) along with Ecm11p; required for the efficient loading of the SC transverse filament protein, Zip1p; promotes SUMOylation of Ecm11p; mutants are delayed in meiotic nuclear division and are defective in synaptonemal complex assembly; transcription is regulated by Ume6p and induced in response to alpha factor

Top 10 interactors (score): ECM11 (0.975); GMC1 (0.892); ZIP1 (0.843); SPO11 (0.826); SPO16 (0.813); RED1 (0.797); ZIP2 (0.779); SPO22 (0.773); CST9 (0.747); YHR202W (0.746); YMR147W (0.707); YDR018C (0.699); MSH4 (0.698); PHO92 (0.695); YHR127W (0.679); HOP2 (0.637); YOL131W (0.631); HOP1 (0.621); YKR005C (0.617); YML6 (0.616)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:962454-963102:+ gene-YLR445W_AKU4011 rna-NM_001182333.3_AKU4011 cds-NP_013550.4_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000048.1:194921-195569:+ gene-YLR445W_BG1 rna-NM_001182333.3_BG1 cds-NP_013550.4_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:1000765-1001413:+ gene-YLR445W_Bruggeman rna-NM_001182333.3_Bruggeman cds-NP_013550.4_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:996767-997415:+ gene-YLR445W_CAT1 rna-NM_001182333.3_CAT1 cds-NP_013550.4_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:998048-998696:+ gene-YLR445W_CBS1585 rna-NM_001182333.3_CBS1585 cds-NP_013550.4_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:987398-988046:+ gene-YLR445W_CBS436 rna-NM_001182333.3_CBS436 cds-NP_013550.4_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:1034086-1034734:+ gene-YLR445W_CBS6412 rna-NM_001182333.3_CBS6412 cds-NP_013550.4_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:998834-999482:+ gene-YLR445W_CBS6413 rna-NM_001182333.3_CBS6413 cds-NP_013550.4_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:1008805-1009448:+ gene-YLR445W_CENPK1137D rna-NM_001182333.3_CENPK1137D cds-NP_013550.4_CENPK1137D 99.1 99.1 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:955477-956125:+ gene-YLR445W_EthanolRed rna-NM_001182333.3_EthanolRed cds-NP_013550.4_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:990748-991396:+ gene-YLR445W_FaliES1 rna-NM_001182333.3_FaliES1 cds-NP_013550.4_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000194.1:27285-27933:- gene-YLR445W_JAY291 rna-NM_001182333.3_JAY291 cds-NP_013550.4_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:999617-1000265:+ gene-YLR445W_MUCL30387 rna-NM_001182333.3_MUCL30387 cds-NP_013550.4_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:1006974-1007622:+ gene-YLR445W_MUCL30388 rna-NM_001182333.3_MUCL30388 cds-NP_013550.4_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:999268-999916:+ gene-YLR445W_MUCL39482 rna-NM_001182333.3_MUCL39482 cds-NP_013550.4_MUCL39482 99.6 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:999765-1000413:+ gene-YLR445W_MUCL42920 rna-NM_001182333.3_MUCL42920 cds-NP_013550.4_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:1024163-1024811:+ gene-YLR445W_NCIM3186 rna-NM_001182333.3_NCIM3186 cds-NP_013550.4_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:1008699-1009347:+ gene-YLR445W_NCYC1407 rna-NM_001182333.3_NCYC1407 cds-NP_013550.4_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:995153-995801:+ gene-YLR445W_PE2H3 rna-NM_001182333.3_PE2H3 cds-NP_013550.4_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:994897-995545:+ gene-YLR445W_PE2H4 rna-NM_001182333.3_PE2H4 cds-NP_013550.4_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:1024189-1024837:+ gene-YLR445W_S288C rna-NM_001182333.3_S288C cds-NP_013550.4_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000007.1:35113-35761:- gene-YLR445W_SA1 rna-NM_001182333.3_SA1 cds-NP_013550.4_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:993827-994475:+ gene-YLR445W_ThermosaccDry rna-NM_001182333.3_ThermosaccDry cds-NP_013550.4_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:1000257-1000905:+ gene-YLR445W_VR1 rna-NM_001182333.3_VR1 cds-NP_013550.4_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:324099-324747:+ gene-YLR445W_ZTW1 rna-NM_001182333.3_ZTW1 cds-NP_013550.4_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:973165-973811:+ gene-YLR445W_Sparadoxus rna-NM_001182333.3_Sparadoxus cds-NP_013550.4_Sparadoxus 89.8 99.8 Verified 1 1 1 False True False False False

Additional files