GLT1 (YDL171C)


Gene profile

Gene name: GLT1
Reference locus (S288C): YDL171C
Gene biotype: protein_coding

Description: NAD(+)-dependent glutamate synthase (GOGAT); synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source; assembles into filaments as cells approach stationary phase and under cytosolic acidification and starvation conditions

Top 10 interactors (score): GLN1 (0.999); GDH3 (0.999); GDH1 (0.999); GDH2 (0.991); GCV2 (0.968); ADE4 (0.968); GCV1 (0.959); CPA1 (0.956); CPA2 (0.95); GAD1 (0.945); URA2 (0.941); GFA1 (0.937); PUT2 (0.932); YMR084W (0.93); IDH1 (0.914); IDH2 (0.912); NIT3 (0.91); CIT1 (0.908); KGD1 (0.9); PRO2 (0.896)

Homologues (species, bitscore): DPYD (Homo sapiens, 83.2); Dpyd (Mus musculus, 84.7); dpydb (Danio rerio, 92.0); ENSXETP00000018792 (Xenopus tropicalis, 62.0); CG9674 (Drosophila melanogaster, 2078.5); W07E11.1 (Caenorhabditis elegans, 1949.1); GLT1 (Arabidopsis thaliana, 2109.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:133619-140056:- gene-YDL171C_AKU4011 rna-NM_001180231.1_AKU4011 cds-NP_010110.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:409674-416111:+ gene-YDL171C_BG1 rna-NM_001180231.1_BG1 cds-NP_010110.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:149680-156117:- gene-YDL171C_Bruggeman rna-NM_001180231.1_Bruggeman cds-NP_010110.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:147990-154427:- gene-YDL171C_CAT1 rna-NM_001180231.1_CAT1 cds-NP_010110.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:131657-138094:- gene-YDL171C_CBS1585 rna-NM_001180231.1_CBS1585 cds-NP_010110.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:148610-155047:- gene-YDL171C_CBS436 rna-NM_001180231.1_CBS436 cds-NP_010110.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:131220-137657:- gene-YDL171C_CBS6412 rna-NM_001180231.1_CBS6412 cds-NP_010110.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:150031-156468:- gene-YDL171C_CBS6413 rna-NM_001180231.1_CBS6413 cds-NP_010110.1_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:147876-154313:- gene-YDL171C_CENPK1137D rna-NM_001180231.1_CENPK1137D cds-NP_010110.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:145033-151470:- gene-YDL171C_EthanolRed rna-NM_001180231.1_EthanolRed cds-NP_010110.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:150359-156796:- gene-YDL171C_FaliES1 rna-NM_001180231.1_FaliES1 cds-NP_010110.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000032.1:62720-69157:+ gene-YDL171C_JAY291 rna-NM_001180231.1_JAY291 cds-NP_010110.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:147977-154414:- gene-YDL171C_MUCL30387 rna-NM_001180231.1_MUCL30387 cds-NP_010110.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:139626-146063:- gene-YDL171C_MUCL30388 rna-NM_001180231.1_MUCL30388 cds-NP_010110.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:132799-139236:- gene-YDL171C_MUCL39482 rna-NM_001180231.1_MUCL39482 cds-NP_010110.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe MBVV01000307.1:30137-36574:+ gene-YDL171C_MUCL42920 rna-NM_001180231.1_MUCL42920 cds-NP_010110.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:149126-155563:- gene-YDL171C_NCIM3186 rna-NM_001180231.1_NCIM3186 cds-NP_010110.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:132688-139125:- gene-YDL171C_NCYC1407 rna-NM_001180231.1_NCYC1407 cds-NP_010110.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:139978-146415:- gene-YDL171C_PE2H3 rna-NM_001180231.1_PE2H3 cds-NP_010110.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:139982-146419:- gene-YDL171C_PE2H4 rna-NM_001180231.1_PE2H4 cds-NP_010110.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:149203-155640:- gene-YDL171C_S288C rna-NM_001180231.1_S288C cds-NP_010110.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000043.1:14755-21192:- gene-YDL171C_SA1 rna-NM_001180231.1_SA1 cds-NP_010110.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:150119-156556:- gene-YDL171C_ThermosaccDry rna-NM_001180231.1_ThermosaccDry cds-NP_010110.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:150749-157186:- gene-YDL171C_VR1 rna-NM_001180231.1_VR1 cds-NP_010110.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:148298-154735:- gene-YDL171C_ZTW1 rna-NM_001180231.1_ZTW1 cds-NP_010110.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:150464-156901:- gene-YDL171C_Sparadoxus rna-NM_001180231.1_Sparadoxus cds-NP_010110.1_Sparadoxus 92.2 99.9 Verified 1 1 1 False True False False False

Additional files