GLR1 (YPL091W)


Gene profile

Gene name: GLR1
Reference locus (S288C): YPL091W
Gene biotype: protein_coding

Description: Cytosolic and mitochondrial glutathione oxidoreductase; converts oxidized glutathione to reduced glutathione; cytosolic Glr1p is the main determinant of the glutathione redox state of the mitochondrial intermembrane space; mitochondrial Glr1p has a role in resistance to hyperoxia; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): GSH2 (0.994); GPX1 (0.993); GPX2 (0.992); GSH1 (0.992); TRR2 (0.989); TRR1 (0.983); URE2 (0.98); PRX1 (0.98); CTT1 (0.979); TRX2 (0.977); CTA1 (0.973); TRX1 (0.973); ECM38 (0.971); GTT1 (0.971); TRX3 (0.97); AHP1 (0.964); ZWF1 (0.96); GRX1 (0.951); GRX2 (0.95); YAP1 (0.942)

Homologues (species, bitscore): GSR (Homo sapiens, 446.4); Gsr (Mus musculus, 452.2); gsr (Danio rerio, 453.0); gsr (Xenopus tropicalis, 430.6); Trxr-1 (Drosophila melanogaster, 257.7); gsr-1 (Caenorhabditis elegans, 426.0); GR (Arabidopsis thaliana, 309.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:353144-354595:+ gene-YPL091W_AKU4011 rna-NM_001183905.1_AKU4011 cds-NP_015234.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:558900-560351:+ gene-YPL091W_BG1 rna-NM_001183905.1_BG1 cds-NP_015234.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:379151-380602:+ gene-YPL091W_Bruggeman rna-NM_001183905.1_Bruggeman cds-NP_015234.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:376616-378067:+ gene-YPL091W_CAT1 rna-NM_001183905.1_CAT1 cds-NP_015234.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:357219-358670:+ gene-YPL091W_CBS1585 rna-NM_001183905.1_CBS1585 cds-NP_015234.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:371890-373341:+ gene-YPL091W_CBS436 rna-NM_001183905.1_CBS436 cds-NP_015234.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:361887-363338:+ gene-YPL091W_CBS6412 rna-NM_001183905.1_CBS6412 cds-NP_015234.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:353853-355304:+ gene-YPL091W_CBS6413 rna-NM_001183905.1_CBS6413 cds-NP_015234.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:375450-376901:+ gene-YPL091W_CENPK1137D rna-NM_001183905.1_CENPK1137D cds-NP_015234.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:351836-353287:+ gene-YPL091W_EthanolRed rna-NM_001183905.1_EthanolRed cds-NP_015234.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:359428-360879:+ gene-YPL091W_FaliES1 rna-NM_001183905.1_FaliES1 cds-NP_015234.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:4937-6388:- gene-YPL091W_JAY291 rna-NM_001183905.1_JAY291 cds-NP_015234.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:370389-371840:+ gene-YPL091W_MUCL30387 rna-NM_001183905.1_MUCL30387 cds-NP_015234.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:594907-596358:+ gene-YPL091W_MUCL30388 rna-NM_001183905.1_MUCL30388 cds-NP_015234.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:350548-351999:+ gene-YPL091W_MUCL39482 rna-NM_001183905.1_MUCL39482 cds-NP_015234.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:408235-409686:+ gene-YPL091W_MUCL42920 rna-NM_001183905.1_MUCL42920 cds-NP_015234.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:375485-376936:+ gene-YPL091W_NCIM3186 rna-NM_001183905.1_NCIM3186 cds-NP_015234.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:356999-358450:+ gene-YPL091W_NCYC1407 rna-NM_001183905.1_NCYC1407 cds-NP_015234.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:364492-365943:+ gene-YPL091W_PE2H3 rna-NM_001183905.1_PE2H3 cds-NP_015234.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:364115-365566:+ gene-YPL091W_PE2H4 rna-NM_001183905.1_PE2H4 cds-NP_015234.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:375502-376953:+ gene-YPL091W_S288C rna-NM_001183905.1_S288C cds-NP_015234.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000138.1:469-1920:- gene-YPL091W_SA1 rna-NM_001183905.1_SA1 cds-NP_015234.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:359226-360677:+ gene-YPL091W_ThermosaccDry rna-NM_001183905.1_ThermosaccDry cds-NP_015234.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:374204-375655:+ gene-YPL091W_VR1 rna-NM_001183905.1_VR1 cds-NP_015234.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:358546-359997:+ gene-YPL091W_ZTW1 rna-NM_001183905.1_ZTW1 cds-NP_015234.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:360180-361631:+ gene-YPL091W_Sparadoxus rna-NM_001183905.1_Sparadoxus cds-NP_015234.1_Sparadoxus 91.7 100.0 Verified 1 1 1 False True False False False

Additional files