GLO4 (YOR040W)


Gene profile

Gene name: GLO4
Reference locus (S288C): YOR040W
Gene biotype: protein_coding

Description: Hydroxyacylglutathione hydrolase, mitochondrial; Mitochondrial glyoxalase II; catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate; GLO4 has a paralog, GLO2, that arose from the whole genome duplication

Top 10 interactors (score): GLO1 (0.999); GLO2 (0.951); HSP31 (0.946); HSP32 (0.936); SNO4 (0.935); HSP33 (0.934); DLD1 (0.915); DLD2 (0.911); DLD3 (0.91); PCM1 (0.754); YNL195C (0.747); ECM38 (0.723); LEE1 (0.697); UGA1 (0.689); GLO3 (0.669); QRI1 (0.641); SOL4 (0.594); GUK1 (0.587); GGC1 (0.568); GUP2 (0.558)

Homologues (species, bitscore): HAGH (Homo sapiens, 142.1); Hagh (Mus musculus, 150.2); hagh (Danio rerio, 151.0); hagh (Xenopus tropicalis, 154.8); CG4365 (Drosophila melanogaster, 141.0); Y17G7B.3 (Caenorhabditis elegans, 140.2); GLY2 (Arabidopsis thaliana, 139.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:391405-392262:+ gene-YOR040W_AKU4011 rna-NM_001183459.1_AKU4011 cds-NP_014683.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:206981-207838:+ gene-YOR040W_BG1 rna-NM_001183459.1_BG1 cds-NP_014683.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:394146-395003:+ gene-YOR040W_Bruggeman rna-NM_001183459.1_Bruggeman cds-NP_014683.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:392299-393156:+ gene-YOR040W_CAT1 rna-NM_001183459.1_CAT1 cds-NP_014683.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:386096-386953:+ gene-YOR040W_CBS1585 rna-NM_001183459.1_CBS1585 cds-NP_014683.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:390450-391307:+ gene-YOR040W_CBS436 rna-NM_001183459.1_CBS436 cds-NP_014683.1_CBS436 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:385450-386307:+ gene-YOR040W_CBS6412 rna-NM_001183459.1_CBS6412 cds-NP_014683.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:392825-393682:+ gene-YOR040W_CBS6413 rna-NM_001183459.1_CBS6413 cds-NP_014683.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:407063-407920:+ gene-YOR040W_CENPK1137D rna-NM_001183459.1_CENPK1137D cds-NP_014683.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:388103-388960:+ gene-YOR040W_EthanolRed rna-NM_001183459.1_EthanolRed cds-NP_014683.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:391451-392308:+ gene-YOR040W_FaliES1 rna-NM_001183459.1_FaliES1 cds-NP_014683.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000035.1:62098-62955:+ gene-YOR040W_JAY291 rna-NM_001183459.1_JAY291 cds-NP_014683.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:398914-399771:+ gene-YOR040W_MUCL30387 rna-NM_001183459.1_MUCL30387 cds-NP_014683.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:402218-403075:+ gene-YOR040W_MUCL30388 rna-NM_001183459.1_MUCL30388 cds-NP_014683.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:393579-394436:+ gene-YOR040W_MUCL39482 rna-NM_001183459.1_MUCL39482 cds-NP_014683.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:408393-409250:+ gene-YOR040W_MUCL42920 rna-NM_001183459.1_MUCL42920 cds-NP_014683.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:406953-407810:+ gene-YOR040W_NCIM3186 rna-NM_001183459.1_NCIM3186 cds-NP_014683.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:400281-401138:+ gene-YOR040W_NCYC1407 rna-NM_001183459.1_NCYC1407 cds-NP_014683.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:399117-399974:+ gene-YOR040W_PE2H3 rna-NM_001183459.1_PE2H3 cds-NP_014683.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:409498-410355:+ gene-YOR040W_PE2H4 rna-NM_001183459.1_PE2H4 cds-NP_014683.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:407064-407921:+ gene-YOR040W_S288C rna-NM_001183459.1_S288C cds-NP_014683.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:374982-375839:+ gene-YOR040W_SA1 rna-NM_001183459.1_SA1 cds-NP_014683.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:389991-390848:+ gene-YOR040W_ThermosaccDry rna-NM_001183459.1_ThermosaccDry cds-NP_014683.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:390880-391737:+ gene-YOR040W_VR1 rna-NM_001183459.1_VR1 cds-NP_014683.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:124618-125475:+ gene-YOR040W_ZTW1 rna-NM_001183459.1_ZTW1 cds-NP_014683.1_ZTW1 99.5 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:397351-398208:+ gene-YOR040W_Sparadoxus rna-NM_001183459.1_Sparadoxus cds-NP_014683.1_Sparadoxus 86.3 100.0 Verified 1 1 1 False True False False False

Additional files