Gene name: GLO2
Reference locus (S288C): YDR272W
Gene biotype: protein_coding
Description: Hydroxyacylglutathione hydrolase, cytoplasmic isozyme; Cytoplasmic glyoxalase II; catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate; GLO2 has a paralog, GLO4, that arose from the whole genome duplication
Top 10 interactors (score): GLO1 (0.998); HSP31 (0.968); GLO4 (0.951); SNO4 (0.933); HSP32 (0.933); HSP33 (0.932); DLD1 (0.911); DLD3 (0.908); DLD2 (0.908); PCM1 (0.754); UGA1 (0.655); QRI1 (0.641); ECM38 (0.607); GLO3 (0.604); GAL2 (0.573); YGL242C (0.562); YDR132C (0.557); RPO26 (0.539); YJL068C (0.537); YCR101C (0.528)
Homologues (species, bitscore): HAGH (Homo sapiens, 166.4); Hagh (Mus musculus, 167.9); hagh (Danio rerio, 159.8); hagh (Xenopus tropicalis, 171.4); CG4365 (Drosophila melanogaster, 154.1); Y17G7B.3 (Caenorhabditis elegans, 161.4); GLY2 (Arabidopsis thaliana, 146.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:961308-962132:+ | gene-YDR272W_AKU4011 | rna-NM_001180580.3_AKU4011 | cds-NP_010558.3_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:170198-171022:- | gene-YDR272W_BG1 | rna-NM_001180580.3_BG1 | cds-NP_010558.3_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:987475-988299:+ | gene-YDR272W_Bruggeman | rna-NM_001180580.3_Bruggeman | cds-NP_010558.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:975319-976143:+ | gene-YDR272W_CAT1 | rna-NM_001180580.3_CAT1 | cds-NP_010558.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:955753-956577:+ | gene-YDR272W_CBS1585 | rna-NM_001180580.3_CBS1585 | cds-NP_010558.3_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:973781-974605:+ | gene-YDR272W_CBS436 | rna-NM_001180580.3_CBS436 | cds-NP_010558.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:952436-953260:+ | gene-YDR272W_CBS6412 | rna-NM_001180580.3_CBS6412 | cds-NP_010558.3_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:973672-974496:+ | gene-YDR272W_CBS6413 | rna-NM_001180580.3_CBS6413 | cds-NP_010558.3_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1007653-1008477:+ | gene-YDR272W_CENPK1137D | rna-NM_001180580.3_CENPK1137D | cds-NP_010558.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:959854-960678:+ | gene-YDR272W_EthanolRed | rna-NM_001180580.3_EthanolRed | cds-NP_010558.3_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:968056-968880:+ | gene-YDR272W_FaliES1 | rna-NM_001180580.3_FaliES1 | cds-NP_010558.3_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000176.1:16309-17133:+ | gene-YDR272W_JAY291 | rna-NM_001180580.3_JAY291 | cds-NP_010558.3_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:973111-973935:+ | gene-YDR272W_MUCL30387 | rna-NM_001180580.3_MUCL30387 | cds-NP_010558.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:960820-961644:+ | gene-YDR272W_MUCL30388 | rna-NM_001180580.3_MUCL30388 | cds-NP_010558.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:947559-948383:+ | gene-YDR272W_MUCL39482 | rna-NM_001180580.3_MUCL39482 | cds-NP_010558.3_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:887551-888375:+ | gene-YDR272W_MUCL42920 | rna-NM_001180580.3_MUCL42920 | cds-NP_010558.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1008933-1009757:+ | gene-YDR272W_NCIM3186 | rna-NM_001180580.3_NCIM3186 | cds-NP_010558.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:960849-961673:+ | gene-YDR272W_NCYC1407 | rna-NM_001180580.3_NCYC1407 | cds-NP_010558.3_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:971476-972300:+ | gene-YDR272W_PE2H3 | rna-NM_001180580.3_PE2H3 | cds-NP_010558.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:976754-977578:+ | gene-YDR272W_PE2H4 | rna-NM_001180580.3_PE2H4 | cds-NP_010558.3_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1009010-1009834:+ | gene-YDR272W_S288C | rna-NM_001180580.3_S288C | cds-NP_010558.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000102.1:16635-17459:+ | gene-YDR272W_SA1 | rna-NM_001180580.3_SA1 | cds-NP_010558.3_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:972341-973165:+ | gene-YDR272W_ThermosaccDry | rna-NM_001180580.3_ThermosaccDry | cds-NP_010558.3_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:987934-988758:+ | gene-YDR272W_VR1 | rna-NM_001180580.3_VR1 | cds-NP_010558.3_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:16465-17289:+ | gene-YDR272W_ZTW1 | rna-NM_001180580.3_ZTW1 | cds-NP_010558.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:968759-969583:+ | gene-YDR272W_Sparadoxus | rna-NM_001180580.3_Sparadoxus | cds-NP_010558.3_Sparadoxus | 90.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |