Gene name: GLO1
Reference locus (S288C): YML004C
Gene biotype: protein_coding
Description: Lactoylglutathione lyase; Monomeric glyoxalase I; catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress
Top 10 interactors (score): GLO4 (0.999); GLO2 (0.998); HSP31 (0.981); HSP32 (0.976); YHR020W (0.966); GRE3 (0.962); HSP33 (0.947); SNO4 (0.947); GRE2 (0.92); TRP5 (0.878); ILV1 (0.865); CHA1 (0.856); DUR1,2 (0.84); DSD1 (0.8); GLR1 (0.8); CYB2 (0.786); CTT1 (0.722); GIM5 (0.722); TPI1 (0.721); DLD1 (0.705)
Homologues (species, bitscore): GLO1 (Homo sapiens, 139.0); Glo1 (Mus musculus, 142.9); glo1 (Danio rerio, 135.6); glo1 (Xenopus tropicalis, 113.6); CG1707 (Drosophila melanogaster, 136.0); AT1G08110 (Arabidopsis thaliana, 139.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:311276-312256:- | gene-YML004C_AKU4011 | rna-NM_001182359.1_AKU4011 | cds-NP_013710.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:230568-231548:+ | gene-YML004C_BG1 | rna-NM_001182359.1_BG1 | cds-NP_013710.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:251245-252225:- | gene-YML004C_Bruggeman | rna-NM_001182359.1_Bruggeman | cds-NP_013710.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:253758-254738:- | gene-YML004C_CAT1 | rna-NM_001182359.1_CAT1 | cds-NP_013710.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:244255-245235:- | gene-YML004C_CBS1585 | rna-NM_001182359.1_CBS1585 | cds-NP_013710.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:249786-250766:- | gene-YML004C_CBS436 | rna-NM_001182359.1_CBS436 | cds-NP_013710.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:358024-359004:- | gene-YML004C_CBS6412 | rna-NM_001182359.1_CBS6412 | cds-NP_013710.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:243510-244490:- | gene-YML004C_CBS6413 | rna-NM_001182359.1_CBS6413 | cds-NP_013710.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:256436-257416:- | gene-YML004C_CENPK1137D | rna-NM_001182359.1_CENPK1137D | cds-NP_013710.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:244290-245270:- | gene-YML004C_EthanolRed | rna-NM_001182359.1_EthanolRed | cds-NP_013710.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:247256-248236:- | gene-YML004C_FaliES1 | rna-NM_001182359.1_FaliES1 | cds-NP_013710.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:188701-189681:+ | gene-YML004C_JAY291 | rna-NM_001182359.1_JAY291 | cds-NP_013710.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:248973-249953:- | gene-YML004C_MUCL30387 | rna-NM_001182359.1_MUCL30387 | cds-NP_013710.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:253639-254619:- | gene-YML004C_MUCL30388 | rna-NM_001182359.1_MUCL30388 | cds-NP_013710.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:244535-245515:- | gene-YML004C_MUCL39482 | rna-NM_001182359.1_MUCL39482 | cds-NP_013710.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:250089-251069:- | gene-YML004C_MUCL42920 | rna-NM_001182359.1_MUCL42920 | cds-NP_013710.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:261659-262639:- | gene-YML004C_NCIM3186 | rna-NM_001182359.1_NCIM3186 | cds-NP_013710.1_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:244470-245450:- | gene-YML004C_NCYC1407 | rna-NM_001182359.1_NCYC1407 | cds-NP_013710.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:250392-251372:- | gene-YML004C_PE2H3 | rna-NM_001182359.1_PE2H3 | cds-NP_013710.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:256487-257467:- | gene-YML004C_PE2H4 | rna-NM_001182359.1_PE2H4 | cds-NP_013710.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:261705-262685:- | gene-YML004C_S288C | rna-NM_001182359.1_S288C | cds-NP_013710.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:275588-276568:+ | gene-YML004C_SA1 | rna-NM_001182359.1_SA1 | cds-NP_013710.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:244318-245298:- | gene-YML004C_ThermosaccDry | rna-NM_001182359.1_ThermosaccDry | cds-NP_013710.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:248279-249259:- | gene-YML004C_VR1 | rna-NM_001182359.1_VR1 | cds-NP_013710.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:223361-224341:- | gene-YML004C_ZTW1 | rna-NM_001182359.1_ZTW1 | cds-NP_013710.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:255784-256764:- | gene-YML004C_Sparadoxus | rna-NM_001182359.1_Sparadoxus | cds-NP_013710.1_Sparadoxus | 90.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |