Gene name: GLK1
Reference locus (S288C): YCL040W
Gene biotype: protein_coding
Description: Glucokinase-1; Glucokinase; catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources; GLK1 has a paralog, EMI2, that arose from the whole genome duplication; Belongs to the hexokinase family
Top 10 interactors (score): HXK2 (0.999); HXK1 (0.999); PGM2 (0.995); NTH1 (0.994); EMI2 (0.994); PGI1 (0.989); FBP1 (0.983); ZWF1 (0.973); PNC1 (0.972); SUC2 (0.97); GSY2 (0.97); ALD4 (0.964); TPS2 (0.963); GNA1 (0.961); TSL1 (0.959); NTH2 (0.954); HSP104 (0.953); PFK1 (0.952); FBA1 (0.951); GLC3 (0.949)
Homologues (species, bitscore): HKDC1 (Homo sapiens, 248.8); Hk2 (Mus musculus, 240.0); hk2 (Danio rerio, 239.6); hk1 (Xenopus tropicalis, 240.4); Hex-A (Drosophila melanogaster, 223.0); F14B4.2 (Caenorhabditis elegans, 240.4); HXK3 (Arabidopsis thaliana, 242.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:52165-53667:+ | gene-YCL040W_AKU4011 | rna-NM_001178685.1_AKU4011 | cds-NP_009890.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000198.1:6460-7962:+ | gene-YCL040W_BG1 | rna-NM_001178685.1_BG1 | cds-NP_009890.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:39980-41482:+ | gene-YCL040W_Bruggeman | rna-NM_001178685.1_Bruggeman | cds-NP_009890.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:52001-53503:+ | gene-YCL040W_CAT1 | rna-NM_001178685.1_CAT1 | cds-NP_009890.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:52890-54392:+ | gene-YCL040W_CBS1585 | rna-NM_001178685.1_CBS1585 | cds-NP_009890.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:51342-52844:+ | gene-YCL040W_CBS436 | rna-NM_001178685.1_CBS436 | cds-NP_009890.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:40298-41800:+ | gene-YCL040W_CBS6412 | rna-NM_001178685.1_CBS6412 | cds-NP_009890.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:51671-53173:+ | gene-YCL040W_CBS6413 | rna-NM_001178685.1_CBS6413 | cds-NP_009890.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:50432-51934:+ | gene-YCL040W_CENPK1137D | rna-NM_001178685.1_CENPK1137D | cds-NP_009890.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:50217-51719:+ | gene-YCL040W_EthanolRed | rna-NM_001178685.1_EthanolRed | cds-NP_009890.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:51171-52673:+ | gene-YCL040W_FaliES1 | rna-NM_001178685.1_FaliES1 | cds-NP_009890.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000225.1:31708-33210:- | gene-YCL040W_JAY291 | rna-NM_001178685.1_JAY291 | cds-NP_009890.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:38608-40110:+ | gene-YCL040W_MUCL30387 | rna-NM_001178685.1_MUCL30387 | cds-NP_009890.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:38854-40356:+ | gene-YCL040W_MUCL30388 | rna-NM_001178685.1_MUCL30388 | cds-NP_009890.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:53232-54734:+ | gene-YCL040W_MUCL39482 | rna-NM_001178685.1_MUCL39482 | cds-NP_009890.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:39378-40880:+ | gene-YCL040W_MUCL42920 | rna-NM_001178685.1_MUCL42920 | cds-NP_009890.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:50470-51972:+ | gene-YCL040W_NCIM3186 | rna-NM_001178685.1_NCIM3186 | cds-NP_009890.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:53567-55069:+ | gene-YCL040W_NCYC1407 | rna-NM_001178685.1_NCYC1407 | cds-NP_009890.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:51299-52801:+ | gene-YCL040W_PE2H3 | rna-NM_001178685.1_PE2H3 | cds-NP_009890.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:51256-52758:+ | gene-YCL040W_PE2H4 | rna-NM_001178685.1_PE2H4 | cds-NP_009890.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:50838-52340:+ | gene-YCL040W_S288C | rna-NM_001178685.1_S288C | cds-NP_009890.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000061.1:37980-39482:+ | gene-YCL040W_SA1 | rna-NM_001178685.1_SA1 | cds-NP_009890.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:51488-52990:+ | gene-YCL040W_ThermosaccDry | rna-NM_001178685.1_ThermosaccDry | cds-NP_009890.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:57798-59300:+ | gene-YCL040W_VR1 | rna-NM_001178685.1_VR1 | cds-NP_009890.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:51693-53195:+ | gene-YCL040W_ZTW1 | rna-NM_001178685.1_ZTW1 | cds-NP_009890.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:81290-82792:+ | gene-YCL040W_Sparadoxus | rna-NM_001178685.1_Sparadoxus | cds-NP_009890.1_Sparadoxus | 91.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |