Gene name: GLE1
Reference locus (S288C): YDL207W
Gene biotype: protein_coding
Description: Cytoplasmic nucleoporin required for polyadenylated mRNA export; contains a nuclear export signal; when bound to inositol hexakisphosphate (IP6), functions as an activator for the Dbp5p ATPase activity at the nuclear pore complex during mRNA export; mediates translation initiation; required for efficient translation termination
Top 10 interactors (score): DBP5 (0.999); NUP159 (0.999); NUP42 (0.999); NUP116 (0.998); GLE2 (0.998); NUP2 (0.995); MEX67 (0.995); NUP100 (0.993); NUP82 (0.993); NUP57 (0.991); NUP84 (0.987); NAB2 (0.987); GFD1 (0.987); NSP1 (0.986); NUP145 (0.985); NUP157 (0.985); NUP192 (0.984); IPK1 (0.984); NUP133 (0.978); NUP85 (0.977)
Homologues (species, bitscore): GLE1 (Homo sapiens, 65.5); Gle1 (Mus musculus, 67.8); gle1 (Danio rerio, 79.3); gle1 (Xenopus tropicalis, 72.0); CG14749 (Drosophila melanogaster, 71.2); GLE1 (Arabidopsis thaliana, 59.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:71735-73351:+ | gene-YDL207W_AKU4011 | rna-NM_001180267.1_AKU4011 | cds-NP_010074.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000101.1:4909-6525:+ | gene-YDL207W_BG1 | rna-NM_001180267.1_BG1 | cds-NP_010074.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:88126-89742:+ | gene-YDL207W_Bruggeman | rna-NM_001180267.1_Bruggeman | cds-NP_010074.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:90237-91853:+ | gene-YDL207W_CAT1 | rna-NM_001180267.1_CAT1 | cds-NP_010074.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:70587-72203:+ | gene-YDL207W_CBS1585 | rna-NM_001180267.1_CBS1585 | cds-NP_010074.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:285490-287106:+ | gene-YDL207W_CBS436 | rna-NM_001180267.1_CBS436 | cds-NP_010074.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:70699-72315:+ | gene-YDL207W_CBS6412 | rna-NM_001180267.1_CBS6412 | cds-NP_010074.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:88245-89861:+ | gene-YDL207W_CBS6413 | rna-NM_001180267.1_CBS6413 | cds-NP_010074.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:86914-88530:+ | gene-YDL207W_CENPK1137D | rna-NM_001180267.1_CENPK1137D | cds-NP_010074.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:84383-85999:+ | gene-YDL207W_EthanolRed | rna-NM_001180267.1_EthanolRed | cds-NP_010074.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:88988-90604:+ | gene-YDL207W_FaliES1 | rna-NM_001180267.1_FaliES1 | cds-NP_010074.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000344.1:28648-30264:- | gene-YDL207W_JAY291 | rna-NM_001180267.1_JAY291 | cds-NP_010074.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:86358-87974:+ | gene-YDL207W_MUCL30387 | rna-NM_001180267.1_MUCL30387 | cds-NP_010074.1_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:75930-77546:+ | gene-YDL207W_MUCL30388 | rna-NM_001180267.1_MUCL30388 | cds-NP_010074.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:71430-73046:+ | gene-YDL207W_MUCL39482 | rna-NM_001180267.1_MUCL39482 | cds-NP_010074.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:87509-89125:+ | gene-YDL207W_MUCL42920 | rna-NM_001180267.1_MUCL42920 | cds-NP_010074.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:88171-89787:+ | gene-YDL207W_NCIM3186 | rna-NM_001180267.1_NCIM3186 | cds-NP_010074.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:71386-73002:+ | gene-YDL207W_NCYC1407 | rna-NM_001180267.1_NCYC1407 | cds-NP_010074.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:79129-80745:+ | gene-YDL207W_PE2H3 | rna-NM_001180267.1_PE2H3 | cds-NP_010074.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:79139-80755:+ | gene-YDL207W_PE2H4 | rna-NM_001180267.1_PE2H4 | cds-NP_010074.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:88248-89864:+ | gene-YDL207W_S288C | rna-NM_001180267.1_S288C | cds-NP_010074.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000126.1:4819-6435:+ | gene-YDL207W_SA1 | rna-NM_001180267.1_SA1 | cds-NP_010074.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:88752-90368:+ | gene-YDL207W_ThermosaccDry | rna-NM_001180267.1_ThermosaccDry | cds-NP_010074.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:89704-91320:+ | gene-YDL207W_VR1 | rna-NM_001180267.1_VR1 | cds-NP_010074.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:87431-89047:+ | gene-YDL207W_ZTW1 | rna-NM_001180267.1_ZTW1 | cds-NP_010074.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:90782-92398:+ | gene-YDL207W_Sparadoxus | rna-NM_001180267.1_Sparadoxus | cds-NP_010074.1_Sparadoxus | 89.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |