Gene name: GLC7
Reference locus (S288C): YER133W
Gene biotype: protein_coding
Description: Serine/threonine-protein phosphatase PP1-2; Type 1 S/T protein phosphatase (PP1) catalytic subunit; involved in glycogen metabolism, sporulation and mitotic progression; interacts with multiple regulatory subunits; regulates actomyosin ring formation; subunit of CPF; recruited to mating projections by Afr1p interaction; regulates nucleocytoplasmic shuttling of Hxk2p; import into the nucleus is inhibited during spindle assembly checkpoint arrest; involved in dephosphorylating Rps6a/b and Bnr1p; Belongs to the PPP phosphatase family. PP-1 subfamily
Top 10 interactors (score): YPI1 (0.999); SSU72 (0.999); BUD14 (0.999); MPE1 (0.999); REG1 (0.999); PTI1 (0.999); PTA1 (0.999); GAC1 (0.999); SDS22 (0.999); SYC1 (0.999); SWD2 (0.999); REF2 (0.999); PAP1 (0.999); YSH1 (0.997); GIP2 (0.996); CFT2 (0.996); BMH1 (0.995); GIP1 (0.995); BNI4 (0.995); CFT1 (0.995)
Homologues (species, bitscore): PPP1CC (Homo sapiens, 555.1); Ppp1cc (Mus musculus, 555.1); ppp1cc (Danio rerio, 552.0); ppp1ca (Xenopus tropicalis, 555.4); Pp1-96A (Drosophila melanogaster, 540.4); gsp-2 (Caenorhabditis elegans, 557.4); TOPP4 (Arabidopsis thaliana, 502.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:425993-427458:+ | gene-YER133W_AKU4011 | rna-NM_001179023.3_AKU4011 | cds-NP_011059.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000018.1:757-2222:+ | gene-YER133W_BG1 | rna-NM_001179023.3_BG1 | cds-NP_011059.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:436457-437928:+ | gene-YER133W_Bruggeman | rna-NM_001179023.3_Bruggeman | cds-NP_011059.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:432519-433984:+ | gene-YER133W_CAT1 | rna-NM_001179023.3_CAT1 | cds-NP_011059.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:425388-426853:+ | gene-YER133W_CBS1585 | rna-NM_001179023.3_CBS1585 | cds-NP_011059.3_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:428130-429593:+ | gene-YER133W_CBS436 | rna-NM_001179023.3_CBS436 | cds-NP_011059.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:424466-425931:+ | gene-YER133W_CBS6412 | rna-NM_001179023.3_CBS6412 | cds-NP_011059.3_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:431795-433260:+ | gene-YER133W_CBS6413 | rna-NM_001179023.3_CBS6413 | cds-NP_011059.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:429873-431335:+ | gene-YER133W_CENPK1137D | rna-NM_001179023.3_CENPK1137D | cds-NP_011059.3_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:425836-427301:+ | gene-YER133W_EthanolRed | rna-NM_001179023.3_EthanolRed | cds-NP_011059.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:426317-427782:+ | gene-YER133W_FaliES1 | rna-NM_001179023.3_FaliES1 | cds-NP_011059.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000028.1:34577-36040:+ | gene-YER133W_JAY291 | rna-NM_001179023.3_JAY291 | cds-NP_011059.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:433405-434868:+ | gene-YER133W_MUCL30387 | rna-NM_001179023.3_MUCL30387 | cds-NP_011059.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:428352-429823:+ | gene-YER133W_MUCL30388 | rna-NM_001179023.3_MUCL30388 | cds-NP_011059.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:424413-425877:+ | gene-YER133W_MUCL39482 | rna-NM_001179023.3_MUCL39482 | cds-NP_011059.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:432898-434362:+ | gene-YER133W_MUCL42920 | rna-NM_001179023.3_MUCL42920 | cds-NP_011059.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:432494-433957:+ | gene-YER133W_NCIM3186 | rna-NM_001179023.3_NCIM3186 | cds-NP_011059.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:429946-431410:+ | gene-YER133W_NCYC1407 | rna-NM_001179023.3_NCYC1407 | cds-NP_011059.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:440529-441992:+ | gene-YER133W_PE2H3 | rna-NM_001179023.3_PE2H3 | cds-NP_011059.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:430470-431933:+ | gene-YER133W_PE2H4 | rna-NM_001179023.3_PE2H4 | cds-NP_011059.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:432495-433958:+ | gene-YER133W_S288C | rna-NM_001179023.3_S288C | cds-NP_011059.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000023.1:142049-143514:+ | gene-YER133W_SA1 | rna-NM_001179023.3_SA1 | cds-NP_011059.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:427115-428580:+ | gene-YER133W_ThermosaccDry | rna-NM_001179023.3_ThermosaccDry | cds-NP_011059.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:429483-430948:+ | gene-YER133W_VR1 | rna-NM_001179023.3_VR1 | cds-NP_011059.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:424240-425705:+ | gene-YER133W_ZTW1 | rna-NM_001179023.3_ZTW1 | cds-NP_011059.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:428222-429681:+ | gene-YER133W_Sparadoxus | rna-NM_001179023.3_Sparadoxus | cds-NP_011059.3_Sparadoxus | 96.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |