GIS2 (YNL255C)


Gene profile

Gene name: GIS2
Reference locus (S288C): YNL255C
Gene biotype: protein_coding

Description: Zinc finger protein GIS2; Translational activator for mRNAs with internal ribosome entry sites; associates with polysomes and binds to a specific subset of mRNAs; localizes to RNA processing bodies (P bodies) and to stress granules; may have a role in translation regulation under stress conditions; ortholog of human ZNF9/CNBP, a gene involved in myotonic dystrophy type 2

Top 10 interactors (score): BRE5 (0.866); SRO9 (0.854); MRT4 (0.849); PAB1 (0.848); RPL10 (0.834); BRX1 (0.82); YFL068W (0.817); RTC4 (0.8); SBP1 (0.792); GIS4 (0.773); NOP1 (0.759); RPL15A (0.758); FOL1 (0.754); NOP4 (0.753); DBP2 (0.749); YDR521W (0.745); YKL102C (0.745); RPS1A (0.743); KRR1 (0.738); RPL13A (0.721)

Homologues (species, bitscore): CNBP (Homo sapiens, 99.8); Cnbp (Mus musculus, 100.9); cnbpa (Danio rerio, 98.2); cnbp (Xenopus tropicalis, 101.3); CG3800 (Drosophila melanogaster, 77.0); K08D12.3 (Caenorhabditis elegans, 82.8); CSDP1 (Arabidopsis thaliana, 93.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:161099-161560:- gene-YNL255C_AKU4011 rna-NM_001183093.1_AKU4011 cds-NP_014144.1_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:65057-65518:- gene-YNL255C_BG1 rna-NM_001183093.1_BG1 cds-NP_014144.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:170922-171383:- gene-YNL255C_Bruggeman rna-NM_001183093.1_Bruggeman cds-NP_014144.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:178217-178678:- gene-YNL255C_CAT1 rna-NM_001183093.1_CAT1 cds-NP_014144.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:161499-161960:- gene-YNL255C_CBS1585 rna-NM_001183093.1_CBS1585 cds-NP_014144.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:156601-157062:- gene-YNL255C_CBS436 rna-NM_001183093.1_CBS436 cds-NP_014144.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:157910-158371:- gene-YNL255C_CBS6412 rna-NM_001183093.1_CBS6412 cds-NP_014144.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:158192-158653:- gene-YNL255C_CBS6413 rna-NM_001183093.1_CBS6413 cds-NP_014144.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:161143-161604:- gene-YNL255C_CENPK1137D rna-NM_001183093.1_CENPK1137D cds-NP_014144.1_CENPK1137D 99.7 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:158750-159211:- gene-YNL255C_EthanolRed rna-NM_001183093.1_EthanolRed cds-NP_014144.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:153485-153946:- gene-YNL255C_FaliES1 rna-NM_001183093.1_FaliES1 cds-NP_014144.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000082.1:64653-65114:- gene-YNL255C_JAY291 rna-NM_001183093.1_JAY291 cds-NP_014144.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:166706-167167:- gene-YNL255C_MUCL30387 rna-NM_001183093.1_MUCL30387 cds-NP_014144.1_MUCL30387 99.3 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:165291-165752:- gene-YNL255C_MUCL30388 rna-NM_001183093.1_MUCL30388 cds-NP_014144.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:158989-159450:- gene-YNL255C_MUCL39482 rna-NM_001183093.1_MUCL39482 cds-NP_014144.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:161257-161718:- gene-YNL255C_MUCL42920 rna-NM_001183093.1_MUCL42920 cds-NP_014144.1_MUCL42920 99.3 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:167298-167759:- gene-YNL255C_NCIM3186 rna-NM_001183093.1_NCIM3186 cds-NP_014144.1_NCIM3186 99.1 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:161094-161555:- gene-YNL255C_NCYC1407 rna-NM_001183093.1_NCYC1407 cds-NP_014144.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:157995-158456:- gene-YNL255C_PE2H3 rna-NM_001183093.1_PE2H3 cds-NP_014144.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:157383-157844:- gene-YNL255C_PE2H4 rna-NM_001183093.1_PE2H4 cds-NP_014144.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:167329-167790:- gene-YNL255C_S288C rna-NM_001183093.1_S288C cds-NP_014144.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000040.1:84500-84961:+ gene-YNL255C_SA1 rna-NM_001183093.1_SA1 cds-NP_014144.1_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:154341-154802:- gene-YNL255C_ThermosaccDry rna-NM_001183093.1_ThermosaccDry cds-NP_014144.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:173252-173713:- gene-YNL255C_VR1 rna-NM_001183093.1_VR1 cds-NP_014144.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:64673-65134:- gene-YNL255C_ZTW1 rna-NM_001183093.1_ZTW1 cds-NP_014144.1_ZTW1 99.5 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:164571-165032:- gene-YNL255C_Sparadoxus rna-NM_001183093.1_Sparadoxus cds-NP_014144.1_Sparadoxus 95.4 100.0 Verified 1 1 1 False True False False False

Additional files