Gene name: GIN4
Reference locus (S288C): YDR507C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase GIN4; Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily
Top 10 interactors (score): CDC12 (0.983); CDC3 (0.981); CDC10 (0.98); SWE1 (0.979); CDC11 (0.978); SHS1 (0.972); NAP1 (0.943); MIH1 (0.865); HSL1 (0.859); KCC4 (0.84); ELM1 (0.828); BUD4 (0.812); BNI5 (0.778); HSL7 (0.777); CDC28 (0.771); SKT5 (0.76); BUD3 (0.759); DNF1 (0.744); CDC42 (0.738); BNI4 (0.735)
Homologues (species, bitscore): BRSK1 (Homo sapiens, 288.1); Brsk1 (Mus musculus, 289.7); si:dkey-16p21.7 (Danio rerio, 278.9); brsk1 (Xenopus tropicalis, 265.0); sff (Drosophila melanogaster, 283.1); sad-1 (Caenorhabditis elegans, 298.1); KIN10 (Arabidopsis thaliana, 271.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1402343-1405795:- | gene-YDR507C_AKU4011 | rna-NM_001180815.3_AKU4011 | cds-NP_010795.3_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:44001-47453:- | gene-YDR507C_BG1 | rna-NM_001180815.3_BG1 | cds-NP_010795.3_BG1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1433665-1437117:- | gene-YDR507C_Bruggeman | rna-NM_001180815.3_Bruggeman | cds-NP_010795.3_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1410841-1414293:- | gene-YDR507C_CAT1 | rna-NM_001180815.3_CAT1 | cds-NP_010795.3_CAT1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1397077-1400529:- | gene-YDR507C_CBS1585 | rna-NM_001180815.3_CBS1585 | cds-NP_010795.3_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1416334-1419762:- | gene-YDR507C_CBS436 | rna-NM_001180815.3_CBS436 | cds-NP_010795.3_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1392227-1395679:- | gene-YDR507C_CBS6412 | rna-NM_001180815.3_CBS6412 | cds-NP_010795.3_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1415731-1419183:- | gene-YDR507C_CBS6413 | rna-NM_001180815.3_CBS6413 | cds-NP_010795.3_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1461052-1464480:- | gene-YDR507C_CENPK1137D | rna-NM_001180815.3_CENPK1137D | cds-NP_010795.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1405632-1409060:- | gene-YDR507C_EthanolRed | rna-NM_001180815.3_EthanolRed | cds-NP_010795.3_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1409185-1412613:- | gene-YDR507C_FaliES1 | rna-NM_001180815.3_FaliES1 | cds-NP_010795.3_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:107544-110996:- | gene-YDR507C_JAY291 | rna-NM_001180815.3_JAY291 | cds-NP_010795.3_JAY291 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1416779-1420207:- | gene-YDR507C_MUCL30387 | rna-NM_001180815.3_MUCL30387 | cds-NP_010795.3_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1398182-1401634:- | gene-YDR507C_MUCL30388 | rna-NM_001180815.3_MUCL30388 | cds-NP_010795.3_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1388566-1392018:- | gene-YDR507C_MUCL39482 | rna-NM_001180815.3_MUCL39482 | cds-NP_010795.3_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1331256-1334684:- | gene-YDR507C_MUCL42920 | rna-NM_001180815.3_MUCL42920 | cds-NP_010795.3_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1462281-1465709:- | gene-YDR507C_NCIM3186 | rna-NM_001180815.3_NCIM3186 | cds-NP_010795.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1401856-1405308:- | gene-YDR507C_NCYC1407 | rna-NM_001180815.3_NCYC1407 | cds-NP_010795.3_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1412811-1416263:- | gene-YDR507C_PE2H3 | rna-NM_001180815.3_PE2H3 | cds-NP_010795.3_PE2H3 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1418277-1421729:- | gene-YDR507C_PE2H4 | rna-NM_001180815.3_PE2H4 | cds-NP_010795.3_PE2H4 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1462358-1465786:- | gene-YDR507C_S288C | rna-NM_001180815.3_S288C | cds-NP_010795.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:151325-154777:+ | gene-YDR507C_SA1 | rna-NM_001180815.3_SA1 | cds-NP_010795.3_SA1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1413407-1416835:- | gene-YDR507C_ThermosaccDry | rna-NM_001180815.3_ThermosaccDry | cds-NP_010795.3_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1429182-1432634:- | gene-YDR507C_VR1 | rna-NM_001180815.3_VR1 | cds-NP_010795.3_VR1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:456074-459502:- | gene-YDR507C_ZTW1 | rna-NM_001180815.3_ZTW1 | cds-NP_010795.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1422264-1425719:- | gene-YDR507C_Sparadoxus | rna-NM_001180815.3_Sparadoxus | cds-NP_010795.3_Sparadoxus | 89.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |