Gene name: GIC2
Reference locus (S288C): YDR309C
Gene biotype: protein_coding
Description: GTPase-interacting component 2; Redundant rho-like GTPase Cdc42p effector; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region; GIC2 has a paralog, GIC1, that arose from the whole genome duplication
Top 10 interactors (score): CDC42 (0.998); CLA4 (0.968); CDC12 (0.938); BEM4 (0.933); RGA1 (0.928); BNI1 (0.928); CDC24 (0.91); RSR1 (0.87); BEM1 (0.861); GIC1 (0.859); STE20 (0.859); BUB2 (0.854); SPA2 (0.838); RRP14 (0.834); BUD6 (0.812); ACT1 (0.81); CDC3 (0.794); STE50 (0.787); MSB1 (0.773); EXO70 (0.753)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1031062-1032213:- | gene-YDR309C_AKU4011 | rna-NM_001180617.1_AKU4011 | cds-NP_010595.1_AKU4011 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:99350-100501:+ | gene-YDR309C_BG1 | rna-NM_001180617.1_BG1 | cds-NP_010595.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1058328-1059479:- | gene-YDR309C_Bruggeman | rna-NM_001180617.1_Bruggeman | cds-NP_010595.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1045330-1046481:- | gene-YDR309C_CAT1 | rna-NM_001180617.1_CAT1 | cds-NP_010595.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1025507-1026658:- | gene-YDR309C_CBS1585 | rna-NM_001180617.1_CBS1585 | cds-NP_010595.1_CBS1585 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1043875-1045026:- | gene-YDR309C_CBS436 | rna-NM_001180617.1_CBS436 | cds-NP_010595.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1022190-1023341:- | gene-YDR309C_CBS6412 | rna-NM_001180617.1_CBS6412 | cds-NP_010595.1_CBS6412 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1043427-1044578:- | gene-YDR309C_CBS6413 | rna-NM_001180617.1_CBS6413 | cds-NP_010595.1_CBS6413 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1077689-1078840:- | gene-YDR309C_CENPK1137D | rna-NM_001180617.1_CENPK1137D | cds-NP_010595.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1029417-1030568:- | gene-YDR309C_EthanolRed | rna-NM_001180617.1_EthanolRed | cds-NP_010595.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1037819-1038970:- | gene-YDR309C_FaliES1 | rna-NM_001180617.1_FaliES1 | cds-NP_010595.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000130.1:55614-56765:- | gene-YDR309C_JAY291 | rna-NM_001180617.1_JAY291 | cds-NP_010595.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1043813-1044964:- | gene-YDR309C_MUCL30387 | rna-NM_001180617.1_MUCL30387 | cds-NP_010595.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1030914-1032065:- | gene-YDR309C_MUCL30388 | rna-NM_001180617.1_MUCL30388 | cds-NP_010595.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1017314-1018465:- | gene-YDR309C_MUCL39482 | rna-NM_001180617.1_MUCL39482 | cds-NP_010595.1_MUCL39482 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:958457-959608:- | gene-YDR309C_MUCL42920 | rna-NM_001180617.1_MUCL42920 | cds-NP_010595.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1078971-1080122:- | gene-YDR309C_NCIM3186 | rna-NM_001180617.1_NCIM3186 | cds-NP_010595.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1030606-1031757:- | gene-YDR309C_NCYC1407 | rna-NM_001180617.1_NCYC1407 | cds-NP_010595.1_NCYC1407 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1041588-1042739:- | gene-YDR309C_PE2H3 | rna-NM_001180617.1_PE2H3 | cds-NP_010595.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1047173-1048324:- | gene-YDR309C_PE2H4 | rna-NM_001180617.1_PE2H4 | cds-NP_010595.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1079048-1080199:- | gene-YDR309C_S288C | rna-NM_001180617.1_S288C | cds-NP_010595.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:55815-56966:- | gene-YDR309C_SA1 | rna-NM_001180617.1_SA1 | cds-NP_010595.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1042092-1043243:- | gene-YDR309C_ThermosaccDry | rna-NM_001180617.1_ThermosaccDry | cds-NP_010595.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1058006-1059157:- | gene-YDR309C_VR1 | rna-NM_001180617.1_VR1 | cds-NP_010595.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:86211-87362:- | gene-YDR309C_ZTW1 | rna-NM_001180617.1_ZTW1 | cds-NP_010595.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1037642-1038790:- | gene-YDR309C_Sparadoxus | rna-NM_001180617.1_Sparadoxus | cds-NP_010595.1_Sparadoxus | 89.1 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |