GIC1 (YHR061C)


Gene profile

Gene name: GIC1
Reference locus (S288C): YHR061C
Gene biotype: protein_coding

Description: GTPase-interacting component 1; Protein involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain; relocalizes from bud neck to nucleus upon DNA replication stress; GIC1 has a paralog, GIC2, that arose from the whole genome duplication

Top 10 interactors (score): CDC42 (0.998); CLA4 (0.979); CDC12 (0.949); BUB2 (0.941); BEM4 (0.924); CDC24 (0.868); BNI1 (0.865); STE20 (0.859); GIC2 (0.859); RSR1 (0.853); BEM1 (0.828); ZDS2 (0.827); RRP14 (0.803); LTE1 (0.781); YMR181C (0.78); MSB1 (0.776); CDC11 (0.77); ACT1 (0.77); TOS2 (0.762); TEM1 (0.75)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:207793-208737:- gene-YHR061C_AKU4011 rna-NM_001179191.1_AKU4011 cds-NP_011928.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:128933-129877:- gene-YHR061C_BG1 rna-NM_001179191.1_BG1 cds-NP_011928.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:215551-216495:- gene-YHR061C_Bruggeman rna-NM_001179191.1_Bruggeman cds-NP_011928.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:210340-211284:- gene-YHR061C_CAT1 rna-NM_001179191.1_CAT1 cds-NP_011928.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:206899-207843:- gene-YHR061C_CBS1585 rna-NM_001179191.1_CBS1585 cds-NP_011928.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:204857-205801:- gene-YHR061C_CBS436 rna-NM_001179191.1_CBS436 cds-NP_011928.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:207131-208075:- gene-YHR061C_CBS6412 rna-NM_001179191.1_CBS6412 cds-NP_011928.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:207963-208907:- gene-YHR061C_CBS6413 rna-NM_001179191.1_CBS6413 cds-NP_011928.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:214697-215641:- gene-YHR061C_CENPK1137D rna-NM_001179191.1_CENPK1137D cds-NP_011928.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:207289-208233:- gene-YHR061C_EthanolRed rna-NM_001179191.1_EthanolRed cds-NP_011928.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:208266-209210:- gene-YHR061C_FaliES1 rna-NM_001179191.1_FaliES1 cds-NP_011928.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000280.1:8097-9041:+ gene-YHR061C_JAY291 rna-NM_001179191.1_JAY291 cds-NP_011928.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:215303-216247:- gene-YHR061C_MUCL30387 rna-NM_001179191.1_MUCL30387 cds-NP_011928.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:215188-216132:- gene-YHR061C_MUCL30388 rna-NM_001179191.1_MUCL30388 cds-NP_011928.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:207184-208128:- gene-YHR061C_MUCL39482 rna-NM_001179191.1_MUCL39482 cds-NP_011928.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:214093-215037:- gene-YHR061C_MUCL42920 rna-NM_001179191.1_MUCL42920 cds-NP_011928.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:221416-222360:- gene-YHR061C_NCIM3186 rna-NM_001179191.1_NCIM3186 cds-NP_011928.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:678825-679769:- gene-YHR061C_NCYC1407 rna-NM_001179191.1_NCYC1407 cds-NP_011928.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:209388-210332:- gene-YHR061C_PE2H3 rna-NM_001179191.1_PE2H3 cds-NP_011928.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:216835-217779:- gene-YHR061C_PE2H4 rna-NM_001179191.1_PE2H4 cds-NP_011928.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:221534-222478:- gene-YHR061C_S288C rna-NM_001179191.1_S288C cds-NP_011928.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:136963-137907:+ gene-YHR061C_SA1 rna-NM_001179191.1_SA1 cds-NP_011928.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:209357-210301:- gene-YHR061C_ThermosaccDry rna-NM_001179191.1_ThermosaccDry cds-NP_011928.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:216997-217941:- gene-YHR061C_VR1 rna-NM_001179191.1_VR1 cds-NP_011928.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:200910-201854:- gene-YHR061C_ZTW1 rna-NM_001179191.1_ZTW1 cds-NP_011928.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:206482-207438:- gene-YHR061C_Sparadoxus rna-NM_001179191.1_Sparadoxus cds-NP_011928.1_Sparadoxus 87.7 100.0 Verified 1 1 1 False True False False False

Additional files