Gene name: GFA1
Reference locus (S288C): YKL104C
Gene biotype: protein_coding
Description: Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Glutamine-fructose-6-phosphate amidotransferase; catalyzes the formation of glucosamine-6-P and glutamate from fructose-6-P and glutamine in the first step of chitin biosynthesis; GFA1 has a paralogous region, comprising ORFs YMR084W-YMR085W, that arose from the whole genome duplication
Top 10 interactors (score): GNA1 (0.997); QRI1 (0.975); PCM1 (0.972); ADE4 (0.967); URA2 (0.962); CPA2 (0.955); PGI1 (0.955); CPA1 (0.944); GLN1 (0.941); GLT1 (0.937); PMI40 (0.932); GCN1 (0.889); CHS3 (0.879); EMW1 (0.855); GLK1 (0.807); YMR084W (0.803); HXK1 (0.791); CHS1 (0.78); YLR446W (0.748); HXK2 (0.742)
Homologues (species, bitscore): GFPT2 (Homo sapiens, 794.3); Gfpt2 (Mus musculus, 796.6); gfpt2 (Danio rerio, 764.6); gfpt1 (Xenopus tropicalis, 770.0); Gfat1 (Drosophila melanogaster, 773.5); F22B3.4 (Caenorhabditis elegans, 733.8); GFAT (Arabidopsis thaliana, 682.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:229772-231925:- | gene-YKL104C_AKU4011 | rna-NM_001179670.1_AKU4011 | cds-NP_012818.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:206890-209043:- | gene-YKL104C_BG1 | rna-NM_001179670.1_BG1 | cds-NP_012818.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:247947-250100:- | gene-YKL104C_Bruggeman | rna-NM_001179670.1_Bruggeman | cds-NP_012818.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:242737-244890:- | gene-YKL104C_CAT1 | rna-NM_001179670.1_CAT1 | cds-NP_012818.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:242011-244164:- | gene-YKL104C_CBS1585 | rna-NM_001179670.1_CBS1585 | cds-NP_012818.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:240603-242756:- | gene-YKL104C_CBS436 | rna-NM_001179670.1_CBS436 | cds-NP_012818.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:226643-228796:- | gene-YKL104C_CBS6412 | rna-NM_001179670.1_CBS6412 | cds-NP_012818.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:242468-244621:- | gene-YKL104C_CBS6413 | rna-NM_001179670.1_CBS6413 | cds-NP_012818.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:242861-245014:- | gene-YKL104C_CENPK1137D | rna-NM_001179670.1_CENPK1137D | cds-NP_012818.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:240464-242617:- | gene-YKL104C_EthanolRed | rna-NM_001179670.1_EthanolRed | cds-NP_012818.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:241277-243430:- | gene-YKL104C_FaliES1 | rna-NM_001179670.1_FaliES1 | cds-NP_012818.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:63603-65756:- | gene-YKL104C_JAY291 | rna-NM_001179670.1_JAY291 | cds-NP_012818.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:249740-251893:- | gene-YKL104C_MUCL30387 | rna-NM_001179670.1_MUCL30387 | cds-NP_012818.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:244139-246292:- | gene-YKL104C_MUCL30388 | rna-NM_001179670.1_MUCL30388 | cds-NP_012818.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:241799-243952:- | gene-YKL104C_MUCL39482 | rna-NM_001179670.1_MUCL39482 | cds-NP_012818.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:246184-248337:- | gene-YKL104C_MUCL42920 | rna-NM_001179670.1_MUCL42920 | cds-NP_012818.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:243209-245362:- | gene-YKL104C_NCIM3186 | rna-NM_001179670.1_NCIM3186 | cds-NP_012818.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:241990-244143:- | gene-YKL104C_NCYC1407 | rna-NM_001179670.1_NCYC1407 | cds-NP_012818.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:249078-251231:- | gene-YKL104C_PE2H3 | rna-NM_001179670.1_PE2H3 | cds-NP_012818.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:245364-247517:- | gene-YKL104C_PE2H4 | rna-NM_001179670.1_PE2H4 | cds-NP_012818.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:243220-245373:- | gene-YKL104C_S288C | rna-NM_001179670.1_S288C | cds-NP_012818.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:159326-161479:- | gene-YKL104C_SA1 | rna-NM_001179670.1_SA1 | cds-NP_012818.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:241982-244135:- | gene-YKL104C_ThermosaccDry | rna-NM_001179670.1_ThermosaccDry | cds-NP_012818.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:241338-243491:- | gene-YKL104C_VR1 | rna-NM_001179670.1_VR1 | cds-NP_012818.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:240544-242697:- | gene-YKL104C_ZTW1 | rna-NM_001179670.1_ZTW1 | cds-NP_012818.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:257524-259677:- | gene-YKL104C_Sparadoxus | rna-NM_001179670.1_Sparadoxus | cds-NP_012818.1_Sparadoxus | 93.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |