GEX1 (YCL073C)


Gene profile

Gene name: GEX1
Reference locus (S288C): YCL073C
Gene biotype: protein_coding

Description: Glutathione exchanger 1; Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication

Top 10 interactors (score): VBA3 (0.806); YMR279C (0.746); AMF1 (0.745); VBA5 (0.738); VBA4 (0.699); VBA2 (0.678); YPL278C (0.651); ATR1 (0.617); NSE3 (0.614); GFD2 (0.613); AFT2 (0.613); VBA1 (0.598); APA1 (0.595); AZR1 (0.586); GIT1 (0.574); KAR5 (0.569); HMRA1 (0.568); MIX23 (0.567); ANS1 (0.523); MRS4 (0.517)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:6961-8808:- gene-YCL073C_AKU4011 rna-NM_001178711.1_AKU4011 cds-NP_009863.2_AKU4011 98.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000031.1:1-1217:- gene-YCL073C_BG1 rna-NM_001178711.1_BG1 cds-NP_009863.2_BG1 65.8 65.8 Verified 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:6609-8705:- gene-YCL073C_CAT1 rna-NM_001178711.1_CAT1 cds-NP_009863.2_CAT1 88.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:7645-9492:- gene-YCL073C_CBS1585 rna-NM_001178711.1_CBS1585 cds-NP_009863.2_CBS1585 98.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:6505-8352:- gene-YCL073C_CBS436 rna-NM_001178711.1_CBS436 cds-NP_009863.2_CBS436 99.7 100.0 Unannotated 1 1 0 False False False False True
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:642681-644528:+ gene-YCL073C_CBS6412 rna-NM_001178711.1_CBS6412 cds-NP_009863.2_CBS6412 98.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:6164-8011:- gene-YCL073C_CBS6413 rna-NM_001178711.1_CBS6413 cds-NP_009863.2_CBS6413 98.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:6168-8025:- gene-YCL073C_CENPK1137D rna-NM_001178711.1_CENPK1137D cds-NP_009863.2_CENPK1137D 85.3 100.0 Unannotated 1 1 0 False False True False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:6185-8032:- gene-YCL073C_EthanolRed rna-NM_001178711.1_EthanolRed cds-NP_009863.2_EthanolRed 98.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:6203-8050:- gene-YCL073C_FaliES1 rna-NM_001178711.1_FaliES1 cds-NP_009863.2_FaliES1 98.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000295.1:4008-5855:+ gene-YCL073C_JAY291 rna-NM_001178711.1_JAY291 cds-NP_009863.2_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:8030-9877:- gene-YCL073C_MUCL39482 rna-NM_001178711.1_MUCL39482 cds-NP_009863.2_MUCL39482 98.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:8111-9958:- gene-YCL073C_NCYC1407 rna-NM_001178711.1_NCYC1407 cds-NP_009863.2_NCYC1407 98.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:6332-8179:- gene-YCL073C_PE2H3 rna-NM_001178711.1_PE2H3 cds-NP_009863.2_PE2H3 98.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:668199-670046:+ gene-YCL073C_PE2H4 rna-NM_001178711.1_PE2H4 cds-NP_009863.2_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:6479-8326:- gene-YCL073C_S288C rna-NM_001178711.1_S288C cds-NP_009863.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000120.1:2898-4745:+ gene-YCL073C_SA1 rna-NM_001178711.1_SA1 cds-NP_009863.2_SA1 92.5 100.0 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:6343-8190:- gene-YCL073C_ThermosaccDry rna-NM_001178711.1_ThermosaccDry cds-NP_009863.2_ThermosaccDry 98.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:659198-661045:+ gene-YCL073C_VR1 rna-NM_001178711.1_VR1 cds-NP_009863.2_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:6216-8063:- gene-YCL073C_ZTW1 rna-NM_001178711.1_ZTW1 cds-NP_009863.2_ZTW1 98.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:6823-8670:- gene-YCL073C_Sparadoxus rna-NM_001178711.1_Sparadoxus cds-NP_009863.2_Sparadoxus 86.1 100.0 Verified 1 1 1 False True False False False

Additional files