Gene name: GEM1
Reference locus (S288C): YAL048C
Gene biotype: protein_coding
Description: Outer mitochondrial membrane GTPase, subunit of the ERMES complex; potential regulatory subunit of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; ortholog of metazoan Miro GTPases
Top 10 interactors (score): MDM10 (0.999); MDM34 (0.996); MDM12 (0.987); MMM1 (0.984); TOM22 (0.972); TOM70 (0.962); TOM40 (0.957); TOM20 (0.955); FIS1 (0.941); BZZ1 (0.94); FZO1 (0.939); ECM25 (0.939); CDC25 (0.935); BUD5 (0.935); SAC7 (0.932); BAG7 (0.932); TOM7 (0.929); SAM37 (0.919); TOM5 (0.911); PAN1 (0.904)
Homologues (species, bitscore): RHOT1 (Homo sapiens, 294.3); Rhot2 (Mus musculus, 299.7); rhot1a (Danio rerio, 293.9); rhot2 (Xenopus tropicalis, 275.4); Miro (Drosophila melanogaster, 290.8); miro-1 (Caenorhabditis elegans, 288.1); MIRO2 (Arabidopsis thaliana, 332.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:37946-39934:- | gene-YAL048C_AKU4011 | rna-NM_001178193.1_AKU4011 | cds-NP_009351.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:25014-27002:- | gene-YAL048C_BG1 | rna-NM_001178193.1_BG1 | cds-NP_009351.1_BG1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:52403-54391:- | gene-YAL048C_Bruggeman | rna-NM_001178193.1_Bruggeman | cds-NP_009351.1_Bruggeman | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:39164-41152:- | gene-YAL048C_CAT1 | rna-NM_001178193.1_CAT1 | cds-NP_009351.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:50967-52955:- | gene-YAL048C_CBS1585 | rna-NM_001178193.1_CBS1585 | cds-NP_009351.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:51209-53197:- | gene-YAL048C_CBS436 | rna-NM_001178193.1_CBS436 | cds-NP_009351.1_CBS436 | 98.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:37112-39100:- | gene-YAL048C_CBS6412 | rna-NM_001178193.1_CBS6412 | cds-NP_009351.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:49230-51218:- | gene-YAL048C_CBS6413 | rna-NM_001178193.1_CBS6413 | cds-NP_009351.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:52857-54845:- | gene-YAL048C_CENPK1137D | rna-NM_001178193.1_CENPK1137D | cds-NP_009351.1_CENPK1137D | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:39360-41348:- | gene-YAL048C_EthanolRed | rna-NM_001178193.1_EthanolRed | cds-NP_009351.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:53302-55290:- | gene-YAL048C_FaliES1 | rna-NM_001178193.1_FaliES1 | cds-NP_009351.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:25253-27241:- | gene-YAL048C_JAY291 | rna-NM_001178193.1_JAY291 | cds-NP_009351.1_JAY291 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:53908-55896:- | gene-YAL048C_MUCL30387 | rna-NM_001178193.1_MUCL30387 | cds-NP_009351.1_MUCL30387 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:50454-52442:- | gene-YAL048C_MUCL30388 | rna-NM_001178193.1_MUCL30388 | cds-NP_009351.1_MUCL30388 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:49771-51759:- | gene-YAL048C_MUCL39482 | rna-NM_001178193.1_MUCL39482 | cds-NP_009351.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:52113-54101:- | gene-YAL048C_MUCL42920 | rna-NM_001178193.1_MUCL42920 | cds-NP_009351.1_MUCL42920 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:52678-54666:- | gene-YAL048C_NCIM3186 | rna-NM_001178193.1_NCIM3186 | cds-NP_009351.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:37636-39624:- | gene-YAL048C_NCYC1407 | rna-NM_001178193.1_NCYC1407 | cds-NP_009351.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:39517-41505:- | gene-YAL048C_PE2H3 | rna-NM_001178193.1_PE2H3 | cds-NP_009351.1_PE2H3 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:39236-41224:- | gene-YAL048C_PE2H4 | rna-NM_001178193.1_PE2H4 | cds-NP_009351.1_PE2H4 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:52801-54789:- | gene-YAL048C_S288C | rna-NM_001178193.1_S288C | cds-NP_009351.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000084.1:27410-29398:- | gene-YAL048C_SA1 | rna-NM_001178193.1_SA1 | cds-NP_009351.1_SA1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:53512-55500:- | gene-YAL048C_ThermosaccDry | rna-NM_001178193.1_ThermosaccDry | cds-NP_009351.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:54776-56764:- | gene-YAL048C_VR1 | rna-NM_001178193.1_VR1 | cds-NP_009351.1_VR1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:25321-27309:- | gene-YAL048C_ZTW1 | rna-NM_001178193.1_ZTW1 | cds-NP_009351.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:43034-45022:- | gene-YAL048C_Sparadoxus | rna-NM_001178193.1_Sparadoxus | cds-NP_009351.1_Sparadoxus | 91.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |