Gene name: GEF1
Reference locus (S288C): YJR040W
Gene biotype: protein_coding
Description: Anion/proton exchange transporter GEF1; Voltage-gated chloride channel; localized to the golgi, the endosomal system, and plasma membrane; involved in cation homeostasis; highly homologous to vertebrate voltage-gated chloride channels; modulates TBSV model (+) RNA virus replication by regulating copper metabolism
Top 10 interactors (score): CCC2 (0.84); RPO41 (0.757); CLC1 (0.755); ATX1 (0.749); FET3 (0.74); IKS1 (0.691); MSH1 (0.67); BSP1 (0.65); ZNF1 (0.618); TRK2 (0.614); NHX1 (0.593); YPR003C (0.587); LPD1 (0.58); MRS2 (0.577); RRP6 (0.572); VHC1 (0.57); TRK1 (0.55); FRE1 (0.55); SMF1 (0.547); SPS19 (0.535)
Homologues (species, bitscore): CLCN5 (Homo sapiens, 377.1); Clcn5 (Mus musculus, 375.9); clcn4 (Danio rerio, 364.4); clcn3 (Xenopus tropicalis, 373.2); ClC-c (Drosophila melanogaster, 360.9); clh-5 (Caenorhabditis elegans, 325.1); CLC-D (Arabidopsis thaliana, 189.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:479445-481784:+ | gene-YJR040W_AKU4011 | rna-NM_001181698.1_AKU4011 | cds-NP_012574.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:131170-133509:- | gene-YJR040W_BG1 | rna-NM_001181698.1_BG1 | cds-NP_012574.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:493482-495821:+ | gene-YJR040W_Bruggeman | rna-NM_001181698.1_Bruggeman | cds-NP_012574.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:497412-499751:+ | gene-YJR040W_CAT1 | rna-NM_001181698.1_CAT1 | cds-NP_012574.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:491024-493363:+ | gene-YJR040W_CBS1585 | rna-NM_001181698.1_CBS1585 | cds-NP_012574.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:509973-512312:+ | gene-YJR040W_CBS436 | rna-NM_001181698.1_CBS436 | cds-NP_012574.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:479230-481569:+ | gene-YJR040W_CBS6412 | rna-NM_001181698.1_CBS6412 | cds-NP_012574.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:481475-483814:+ | gene-YJR040W_CBS6413 | rna-NM_001181698.1_CBS6413 | cds-NP_012574.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:490114-492453:+ | gene-YJR040W_CENPK1137D | rna-NM_001181698.1_CENPK1137D | cds-NP_012574.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:484375-486714:+ | gene-YJR040W_EthanolRed | rna-NM_001181698.1_EthanolRed | cds-NP_012574.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:495592-497931:+ | gene-YJR040W_FaliES1 | rna-NM_001181698.1_FaliES1 | cds-NP_012574.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000250.1:10441-12780:+ | gene-YJR040W_JAY291 | rna-NM_001181698.1_JAY291 | cds-NP_012574.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:493792-496131:+ | gene-YJR040W_MUCL30387 | rna-NM_001181698.1_MUCL30387 | cds-NP_012574.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:490339-492678:+ | gene-YJR040W_MUCL30388 | rna-NM_001181698.1_MUCL30388 | cds-NP_012574.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:484484-486823:+ | gene-YJR040W_MUCL39482 | rna-NM_001181698.1_MUCL39482 | cds-NP_012574.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:489746-492085:+ | gene-YJR040W_MUCL42920 | rna-NM_001181698.1_MUCL42920 | cds-NP_012574.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:507725-510064:+ | gene-YJR040W_NCIM3186 | rna-NM_001181698.1_NCIM3186 | cds-NP_012574.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:482327-484666:+ | gene-YJR040W_NCYC1407 | rna-NM_001181698.1_NCYC1407 | cds-NP_012574.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:500662-503001:+ | gene-YJR040W_PE2H3 | rna-NM_001181698.1_PE2H3 | cds-NP_012574.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:494358-496697:+ | gene-YJR040W_PE2H4 | rna-NM_001181698.1_PE2H4 | cds-NP_012574.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:507746-510085:+ | gene-YJR040W_S288C | rna-NM_001181698.1_S288C | cds-NP_012574.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:292252-294591:+ | gene-YJR040W_SA1 | rna-NM_001181698.1_SA1 | cds-NP_012574.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:489280-491619:+ | gene-YJR040W_ThermosaccDry | rna-NM_001181698.1_ThermosaccDry | cds-NP_012574.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:491512-493851:+ | gene-YJR040W_VR1 | rna-NM_001181698.1_VR1 | cds-NP_012574.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:469165-471504:+ | gene-YJR040W_ZTW1 | rna-NM_001181698.1_ZTW1 | cds-NP_012574.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:493898-496228:+ | gene-YJR040W_Sparadoxus | rna-NM_001181698.1_Sparadoxus | cds-NP_012574.1_Sparadoxus | 90.2 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |