GEA2 (YEL022W)


Gene profile

Gene name: GEA2
Reference locus (S288C): YEL022W
Gene biotype: protein_coding

Description: Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA2 has a paralog, GEA1, that arose from the whole genome duplication

Top 10 interactors (score): ARF1 (0.997); ARF2 (0.989); COP1 (0.988); SEC21 (0.984); ARL1 (0.977); ARF3 (0.974); GEA1 (0.969); DRS2 (0.965); SEC7 (0.963); GLO3 (0.961); SEC26 (0.951); USO1 (0.944); YPT1 (0.929); PFY1 (0.929); PIK1 (0.918); GCS1 (0.913); AGE2 (0.91); YEL1 (0.857); RET2 (0.849); YPT31 (0.843)

Homologues (species, bitscore): GBF1 (Homo sapiens, 271.9); Gbf1 (Mus musculus, 266.5); gbf1 (Danio rerio, 273.1); gbf1 (Xenopus tropicalis, 288.9); garz (Drosophila melanogaster, 251.1); gbf-1 (Caenorhabditis elegans, 278.1); GN (Arabidopsis thaliana, 250.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:105456-109835:+ gene-YEL022W_AKU4011 rna-NM_001178837.1_AKU4011 cds-NP_010892.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:316125-320504:- gene-YEL022W_BG1 rna-NM_001178837.1_BG1 cds-NP_010892.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:110857-115236:+ gene-YEL022W_Bruggeman rna-NM_001178837.1_Bruggeman cds-NP_010892.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:107639-112018:+ gene-YEL022W_CAT1 rna-NM_001178837.1_CAT1 cds-NP_010892.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:105397-109776:+ gene-YEL022W_CBS1585 rna-NM_001178837.1_CBS1585 cds-NP_010892.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:107030-111409:+ gene-YEL022W_CBS436 rna-NM_001178837.1_CBS436 cds-NP_010892.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:105676-110055:+ gene-YEL022W_CBS6412 rna-NM_001178837.1_CBS6412 cds-NP_010892.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:110289-114668:+ gene-YEL022W_CBS6413 rna-NM_001178837.1_CBS6413 cds-NP_010892.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:109280-113659:+ gene-YEL022W_CENPK1137D rna-NM_001178837.1_CENPK1137D cds-NP_010892.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:105787-110166:+ gene-YEL022W_EthanolRed rna-NM_001178837.1_EthanolRed cds-NP_010892.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:106046-110425:+ gene-YEL022W_FaliES1 rna-NM_001178837.1_FaliES1 cds-NP_010892.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000398.1:24931-29310:+ gene-YEL022W_JAY291 rna-NM_001178837.1_JAY291 cds-NP_010892.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:109710-114089:+ gene-YEL022W_MUCL30387 rna-NM_001178837.1_MUCL30387 cds-NP_010892.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:105682-110061:+ gene-YEL022W_MUCL30388 rna-NM_001178837.1_MUCL30388 cds-NP_010892.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:104766-109145:+ gene-YEL022W_MUCL39482 rna-NM_001178837.1_MUCL39482 cds-NP_010892.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:109396-113775:+ gene-YEL022W_MUCL42920 rna-NM_001178837.1_MUCL42920 cds-NP_010892.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:111420-115799:+ gene-YEL022W_NCIM3186 rna-NM_001178837.1_NCIM3186 cds-NP_010892.1_NCIM3186 98.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:109866-114245:+ gene-YEL022W_NCYC1407 rna-NM_001178837.1_NCYC1407 cds-NP_010892.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:113897-118276:+ gene-YEL022W_PE2H3 rna-NM_001178837.1_PE2H3 cds-NP_010892.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:109812-114191:+ gene-YEL022W_PE2H4 rna-NM_001178837.1_PE2H4 cds-NP_010892.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:111421-115800:+ gene-YEL022W_S288C rna-NM_001178837.1_S288C cds-NP_010892.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:127431-131810:- gene-YEL022W_SA1 rna-NM_001178837.1_SA1 cds-NP_010892.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:106451-110830:+ gene-YEL022W_ThermosaccDry rna-NM_001178837.1_ThermosaccDry cds-NP_010892.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:105986-110365:+ gene-YEL022W_VR1 rna-NM_001178837.1_VR1 cds-NP_010892.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:104809-109187:+ gene-YEL022W_ZTW1 rna-NM_001178837.1_ZTW1 cds-NP_010892.1_ZTW1 99.6 99.9 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:107988-112363:+ gene-YEL022W_Sparadoxus rna-NM_001178837.1_Sparadoxus cds-NP_010892.1_Sparadoxus 91.2 99.8 Verified 1 1 0 False False False True False

Additional files