Gene name: GDT1
Reference locus (S288C): YBR187W
Gene biotype: protein_coding
Description: GCR1-dependent translation factor 1; Calcium transporter localized to the cis- and medial-Golgi apparatus; required for protein glycosylation; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant; Belongs to the GDT1 family
Top 10 interactors (score): PMR1 (0.967); VCX1 (0.933); RCH1 (0.906); DML1 (0.816); CCH1 (0.815); PMC1 (0.797); TMN2 (0.794); YIL067C (0.78); UIP5 (0.78); YNL115C (0.749); YOR292C (0.745); YKL077W (0.744); SMF2 (0.719); SPF1 (0.704); YVC1 (0.698); ECM7 (0.692); ATX2 (0.688); WBP1 (0.678); GOS1 (0.668); STV1 (0.652)
Homologues (species, bitscore): TMEM165 (Homo sapiens, 170.6); Tmem165 (Mus musculus, 169.5); tmem165 (Danio rerio, 159.5); tmem165 (Xenopus tropicalis, 90.1); CG42542 (Drosophila melanogaster, 119.8); Y54F10AL.1 (Caenorhabditis elegans, 146.4); AT1G68650 (Arabidopsis thaliana, 147.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:586003-586845:+ | gene-YBR187W_AKU4011 | rna-NM_001178535.1_AKU4011 | cds-NP_009746.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:576009-576851:+ | gene-YBR187W_BG1 | rna-NM_001178535.1_BG1 | cds-NP_009746.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:391864-392706:+ | gene-YBR187W_Bruggeman | rna-NM_001178535.1_Bruggeman | cds-NP_009746.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:591270-592112:+ | gene-YBR187W_CAT1 | rna-NM_001178535.1_CAT1 | cds-NP_009746.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:577784-578626:+ | gene-YBR187W_CBS1585 | rna-NM_001178535.1_CBS1585 | cds-NP_009746.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:585337-586179:+ | gene-YBR187W_CBS436 | rna-NM_001178535.1_CBS436 | cds-NP_009746.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:674393-675235:+ | gene-YBR187W_CBS6412 | rna-NM_001178535.1_CBS6412 | cds-NP_009746.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:583590-584432:+ | gene-YBR187W_CBS6413 | rna-NM_001178535.1_CBS6413 | cds-NP_009746.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:596408-597250:+ | gene-YBR187W_CENPK1137D | rna-NM_001178535.1_CENPK1137D | cds-NP_009746.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:711160-712002:+ | gene-YBR187W_EthanolRed | rna-NM_001178535.1_EthanolRed | cds-NP_009746.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:602071-602913:+ | gene-YBR187W_FaliES1 | rna-NM_001178535.1_FaliES1 | cds-NP_009746.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000104.1:3306-4147:- | gene-YBR187W_JAY291 | rna-NM_001178535.1_JAY291 | cds-NP_009746.1_JAY291 | 99.1 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:590545-591387:+ | gene-YBR187W_MUCL30387 | rna-NM_001178535.1_MUCL30387 | cds-NP_009746.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:607620-608462:+ | gene-YBR187W_MUCL30388 | rna-NM_001178535.1_MUCL30388 | cds-NP_009746.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:576157-576999:+ | gene-YBR187W_MUCL39482 | rna-NM_001178535.1_MUCL39482 | cds-NP_009746.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:585579-586421:+ | gene-YBR187W_MUCL42920 | rna-NM_001178535.1_MUCL42920 | cds-NP_009746.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:602431-603273:+ | gene-YBR187W_NCIM3186 | rna-NM_001178535.1_NCIM3186 | cds-NP_009746.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:578265-579107:+ | gene-YBR187W_NCYC1407 | rna-NM_001178535.1_NCYC1407 | cds-NP_009746.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:590881-591723:+ | gene-YBR187W_PE2H3 | rna-NM_001178535.1_PE2H3 | cds-NP_009746.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:588557-589399:+ | gene-YBR187W_PE2H4 | rna-NM_001178535.1_PE2H4 | cds-NP_009746.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:602634-603476:+ | gene-YBR187W_S288C | rna-NM_001178535.1_S288C | cds-NP_009746.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000080.1:10332-11174:+ | gene-YBR187W_SA1 | rna-NM_001178535.1_SA1 | cds-NP_009746.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:601081-601923:+ | gene-YBR187W_ThermosaccDry | rna-NM_001178535.1_ThermosaccDry | cds-NP_009746.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:582258-583100:+ | gene-YBR187W_VR1 | rna-NM_001178535.1_VR1 | cds-NP_009746.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:575698-576540:+ | gene-YBR187W_ZTW1 | rna-NM_001178535.1_ZTW1 | cds-NP_009746.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:617534-618385:+ | gene-YBR187W_Sparadoxus | rna-NM_001178535.1_Sparadoxus | cds-NP_009746.1_Sparadoxus | 88.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |