GDH3 (YAL062W)


Gene profile

Gene name: GDH3
Reference locus (S288C): YAL062W
Gene biotype: protein_coding

Description: NADP(+)-dependent glutamate dehydrogenase; synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; GDH3 has a paralog, GDH1, that arose from the whole genome duplication; Belongs to the Glu/Leu/Phe/Val dehydrogenases family

Top 10 interactors (score): GDH1 (0.999); GLT1 (0.999); GLN1 (0.996); GDH2 (0.992); PUT2 (0.977); AAT1 (0.977); ALT1 (0.969); AAT2 (0.969); GAD1 (0.967); GCV1 (0.949); ALT2 (0.934); NIT3 (0.927); KGD1 (0.926); ARG2 (0.923); ARG7 (0.918); NIT1 (0.918); CIT2 (0.918); PCK1 (0.917); CIT1 (0.914); LPD1 (0.912)

Homologues (species, bitscore): GLUD1 (Homo sapiens, 127.1); Glud1 (Mus musculus, 128.6); glud1a (Danio rerio, 120.9); glud1 (Xenopus tropicalis, 102.4); CG4434 (Drosophila melanogaster, 134.0); gdh-1 (Caenorhabditis elegans, 107.5); AT1G51720 (Arabidopsis thaliana, 328.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005295.1:16713-18086:+ gene-YAL062W_AKU4011 rna-NM_001178204.1_AKU4011 cds-NP_009339.1_AKU4011 99.1 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000070.1:3799-5172:+ gene-YAL062W_BG1 rna-NM_001178204.1_BG1 cds-NP_009339.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005503.1:30272-31645:+ gene-YAL062W_Bruggeman rna-NM_001178204.1_Bruggeman cds-NP_009339.1_Bruggeman 99.2 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005519.1:16638-18011:+ gene-YAL062W_CAT1 rna-NM_001178204.1_CAT1 cds-NP_009339.1_CAT1 99.3 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005359.1:29737-31110:+ gene-YAL062W_CBS1585 rna-NM_001178204.1_CBS1585 cds-NP_009339.1_CBS1585 99.1 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005343.1:29977-31350:+ gene-YAL062W_CBS436 rna-NM_001178204.1_CBS436 cds-NP_009339.1_CBS436 99.1 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005327.1:15876-17249:+ gene-YAL062W_CBS6412 rna-NM_001178204.1_CBS6412 cds-NP_009339.1_CBS6412 99.1 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005311.1:27997-29370:+ gene-YAL062W_CBS6413 rna-NM_001178204.1_CBS6413 cds-NP_009339.1_CBS6413 99.1 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001522.1:31625-32998:+ gene-YAL062W_CENPK1137D rna-NM_001178204.1_CENPK1137D cds-NP_009339.1_CENPK1137D 99.1 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005471.1:18130-19503:+ gene-YAL062W_EthanolRed rna-NM_001178204.1_EthanolRed cds-NP_009339.1_EthanolRed 99.1 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005535.1:32073-33446:+ gene-YAL062W_FaliES1 rna-NM_001178204.1_FaliES1 cds-NP_009339.1_FaliES1 99.1 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000084.1:4021-5394:+ gene-YAL062W_JAY291 rna-NM_001178204.1_JAY291 cds-NP_009339.1_JAY291 98.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005407.1:32677-34051:+ gene-YAL062W_MUCL30387 rna-NM_001178204.1_MUCL30387 cds-NP_009339.1_MUCL30387 99.4 100.0 Unannotated 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005439.1:29222-30595:+ gene-YAL062W_MUCL30388 rna-NM_001178204.1_MUCL30388 cds-NP_009339.1_MUCL30388 99.1 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005279.1:28539-29912:+ gene-YAL062W_MUCL39482 rna-NM_001178204.1_MUCL39482 cds-NP_009339.1_MUCL39482 99.1 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005423.1:30879-32252:+ gene-YAL062W_MUCL42920 rna-NM_001178204.1_MUCL42920 cds-NP_009339.1_MUCL42920 99.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011810.1:31444-32817:+ gene-YAL062W_NCIM3186 rna-NM_001178204.1_NCIM3186 cds-NP_009339.1_NCIM3186 98.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005263.1:16403-17776:+ gene-YAL062W_NCYC1407 rna-NM_001178204.1_NCYC1407 cds-NP_009339.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994140.1:18280-19653:+ gene-YAL062W_PE2H3 rna-NM_001178204.1_PE2H3 cds-NP_009339.1_PE2H3 98.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999872.1:18001-19374:+ gene-YAL062W_PE2H4 rna-NM_001178204.1_PE2H4 cds-NP_009339.1_PE2H4 98.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001133.9:31567-32940:+ gene-YAL062W_S288C rna-NM_001178204.1_S288C cds-NP_009339.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000084.1:6178-7551:+ gene-YAL062W_SA1 rna-NM_001178204.1_SA1 cds-NP_009339.1_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005487.1:32282-33655:+ gene-YAL062W_ThermosaccDry rna-NM_001178204.1_ThermosaccDry cds-NP_009339.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005455.1:33041-34414:+ gene-YAL062W_VR1 rna-NM_001178204.1_VR1 cds-NP_009339.1_VR1 99.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000002.1:4091-5464:+ gene-YAL062W_ZTW1 rna-NM_001178204.1_ZTW1 cds-NP_009339.1_ZTW1 99.4 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047487.1:21784-23157:+ gene-YAL062W_Sparadoxus rna-NM_001178204.1_Sparadoxus cds-NP_009339.1_Sparadoxus 90.6 100.0 Verified 1 1 1 False True False False False

Additional files