Gene name: GDH1
Reference locus (S288C): YOR375C
Gene biotype: protein_coding
Description: NADP(+)-dependent glutamate dehydrogenase; synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources; GDH1 has a paralog, GDH3, that arose from the whole genome duplication
Top 10 interactors (score): GDH3 (0.999); GLT1 (0.999); GLN1 (0.997); GDH2 (0.996); PUT2 (0.971); AAT2 (0.964); AAT1 (0.963); GAD1 (0.959); ZWF1 (0.956); ALT1 (0.945); KGD1 (0.941); GCV1 (0.939); ALT2 (0.933); NIT3 (0.927); NIT1 (0.927); ARG7 (0.927); ALD6 (0.926); IDP2 (0.924); ARG2 (0.923); IDH2 (0.918)
Homologues (species, bitscore): GLUD2 (Homo sapiens, 125.6); Glud1 (Mus musculus, 124.0); glud1a (Danio rerio, 117.9); glud1 (Xenopus tropicalis, 94.7); CG4434 (Drosophila melanogaster, 130.2); gdh-1 (Caenorhabditis elegans, 114.0); AT1G51720 (Arabidopsis thaliana, 323.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:1028271-1029635:- | gene-YOR375C_AKU4011 | rna-NM_001183795.3_AKU4011 | cds-NP_015020.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000183.1:31880-33244:+ | gene-YOR375C_BG1 | rna-NM_001183795.3_BG1 | cds-NP_015020.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:1013070-1014434:- | gene-YOR375C_Bruggeman | rna-NM_001183795.3_Bruggeman | cds-NP_015020.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:1013745-1015109:- | gene-YOR375C_CAT1 | rna-NM_001183795.3_CAT1 | cds-NP_015020.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:1012681-1014045:- | gene-YOR375C_CBS1585 | rna-NM_001183795.3_CBS1585 | cds-NP_015020.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:1007493-1008857:- | gene-YOR375C_CBS436 | rna-NM_001183795.3_CBS436 | cds-NP_015020.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:241618-242982:- | gene-YOR375C_CBS6412 | rna-NM_001183795.3_CBS6412 | cds-NP_015020.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:1016955-1018319:- | gene-YOR375C_CBS6413 | rna-NM_001183795.3_CBS6413 | cds-NP_015020.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:1041534-1042898:- | gene-YOR375C_CENPK1137D | rna-NM_001183795.3_CENPK1137D | cds-NP_015020.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:256801-258165:- | gene-YOR375C_EthanolRed | rna-NM_001183795.3_EthanolRed | cds-NP_015020.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:1009809-1011173:- | gene-YOR375C_FaliES1 | rna-NM_001183795.3_FaliES1 | cds-NP_015020.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000314.1:4162-5526:- | gene-YOR375C_JAY291 | rna-NM_001183795.3_JAY291 | cds-NP_015020.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:1022404-1023768:- | gene-YOR375C_MUCL30387 | rna-NM_001183795.3_MUCL30387 | cds-NP_015020.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:1030431-1031795:- | gene-YOR375C_MUCL30388 | rna-NM_001183795.3_MUCL30388 | cds-NP_015020.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:1019201-1020565:- | gene-YOR375C_MUCL39482 | rna-NM_001183795.3_MUCL39482 | cds-NP_015020.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:1026822-1028186:- | gene-YOR375C_MUCL42920 | rna-NM_001183795.3_MUCL42920 | cds-NP_015020.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:1041567-1042931:- | gene-YOR375C_NCIM3186 | rna-NM_001183795.3_NCIM3186 | cds-NP_015020.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:1020221-1021585:- | gene-YOR375C_NCYC1407 | rna-NM_001183795.3_NCYC1407 | cds-NP_015020.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:1015516-1016880:- | gene-YOR375C_PE2H3 | rna-NM_001183795.3_PE2H3 | cds-NP_015020.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:1031867-1033231:- | gene-YOR375C_PE2H4 | rna-NM_001183795.3_PE2H4 | cds-NP_015020.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:1041678-1043042:- | gene-YOR375C_S288C | rna-NM_001183795.3_S288C | cds-NP_015020.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:146280-147644:- | gene-YOR375C_SA1 | rna-NM_001183795.3_SA1 | cds-NP_015020.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:1008991-1010355:- | gene-YOR375C_ThermosaccDry | rna-NM_001183795.3_ThermosaccDry | cds-NP_015020.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:1070497-1071861:- | gene-YOR375C_VR1 | rna-NM_001183795.3_VR1 | cds-NP_015020.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:741717-743081:- | gene-YOR375C_ZTW1 | rna-NM_001183795.3_ZTW1 | cds-NP_015020.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:1015702-1017066:- | gene-YOR375C_Sparadoxus | rna-NM_001183795.3_Sparadoxus | cds-NP_015020.3_Sparadoxus | 93.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |