GDB1 (YPR184W)


Gene profile

Gene name: GDB1
Reference locus (S288C): YPR184W
Gene biotype: protein_coding

Description: Bifunctional 4-alpha-glucanotransferase/amylo-alpha-1,6-glucosidase; Glycogen debranching enzyme; contains glucanotranferase and alpha-1,6-amyloglucosidase activities; required for glycogen degradation; phosphorylated in mitochondria; activity is inhibited by Igd1p; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): GLC3 (0.999); GPH1 (0.999); PGM2 (0.997); SGA1 (0.996); GSY2 (0.991); IGD1 (0.979); UGP1 (0.977); GLG2 (0.974); SOL4 (0.958); GAD1 (0.953); PGM1 (0.95); TFS1 (0.949); TSL1 (0.939); YHL012W (0.939); RTN2 (0.932); GSY1 (0.929); YMR196W (0.927); DCS2 (0.927); MSC1 (0.927); GIP2 (0.923)

Homologues (species, bitscore): AGL (Homo sapiens, 949.5); Agl (Mus musculus, 964.1); agla (Danio rerio, 926.8); agl (Xenopus tropicalis, 952.6); CG9485 (Drosophila melanogaster, 847.8); agl-1 (Caenorhabditis elegans, 830.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:856320-860930:+ gene-YPR184W_AKU4011 rna-NM_001184281.1_AKU4011 cds-NP_015510.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:36780-41390:- gene-YPR184W_BG1 rna-NM_001184281.1_BG1 cds-NP_015510.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:937601-942211:+ gene-YPR184W_Bruggeman rna-NM_001184281.1_Bruggeman cds-NP_015510.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:979660-984270:+ gene-YPR184W_CAT1 rna-NM_001184281.1_CAT1 cds-NP_015510.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:861120-865730:+ gene-YPR184W_CBS1585 rna-NM_001184281.1_CBS1585 cds-NP_015510.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:874666-879276:+ gene-YPR184W_CBS436 rna-NM_001184281.1_CBS436 cds-NP_015510.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:862904-867514:+ gene-YPR184W_CBS6412 rna-NM_001184281.1_CBS6412 cds-NP_015510.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:858049-862659:+ gene-YPR184W_CBS6413 rna-NM_001184281.1_CBS6413 cds-NP_015510.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:902120-906730:+ gene-YPR184W_CENPK1137D rna-NM_001184281.1_CENPK1137D cds-NP_015510.1_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:1178071-1182681:+ gene-YPR184W_EthanolRed rna-NM_001184281.1_EthanolRed cds-NP_015510.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:858144-862754:+ gene-YPR184W_FaliES1 rna-NM_001184281.1_FaliES1 cds-NP_015510.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000081.1:45451-50061:+ gene-YPR184W_JAY291 rna-NM_001184281.1_JAY291 cds-NP_015510.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:904834-909444:+ gene-YPR184W_MUCL30387 rna-NM_001184281.1_MUCL30387 cds-NP_015510.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:878965-883575:+ gene-YPR184W_MUCL30388 rna-NM_001184281.1_MUCL30388 cds-NP_015510.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:853321-857931:+ gene-YPR184W_MUCL39482 rna-NM_001184281.1_MUCL39482 cds-NP_015510.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:917794-922404:+ gene-YPR184W_MUCL42920 rna-NM_001184281.1_MUCL42920 cds-NP_015510.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:902027-906637:+ gene-YPR184W_NCIM3186 rna-NM_001184281.1_NCIM3186 cds-NP_015510.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:861683-866293:+ gene-YPR184W_NCYC1407 rna-NM_001184281.1_NCYC1407 cds-NP_015510.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:873975-878585:+ gene-YPR184W_PE2H3 rna-NM_001184281.1_PE2H3 cds-NP_015510.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:873623-878233:+ gene-YPR184W_PE2H4 rna-NM_001184281.1_PE2H4 cds-NP_015510.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:902044-906654:+ gene-YPR184W_S288C rna-NM_001184281.1_S288C cds-NP_015510.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000060.1:19156-23766:- gene-YPR184W_SA1 rna-NM_001184281.1_SA1 cds-NP_015510.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:857832-862442:+ gene-YPR184W_ThermosaccDry rna-NM_001184281.1_ThermosaccDry cds-NP_015510.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:885630-890240:+ gene-YPR184W_VR1 rna-NM_001184281.1_VR1 cds-NP_015510.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:860377-864987:+ gene-YPR184W_ZTW1 rna-NM_001184281.1_ZTW1 cds-NP_015510.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:862444-867054:+ gene-YPR184W_Sparadoxus rna-NM_001184281.1_Sparadoxus cds-NP_015510.1_Sparadoxus 89.9 99.9 Verified 1 1 1 False True False False False

Additional files