GDA1 (YEL042W)


Gene profile

Gene name: GDA1
Reference locus (S288C): YEL042W
Gene biotype: protein_coding

Description: Guanosine-diphosphatase; Guanosine diphosphatase located in the Golgi; involved in the transport of GDP-mannose into the Golgi lumen, converting GDP to GMP after mannose is transferred to substrates; null mutants are defective in sporulation and pre-meiotic S phase entry; orthologous to human ENTPD6, a meiosis-associated non-obstructive azoospermia (NOA) related gene identified in GWAS studies; Belongs to the GDA1/CD39 NTPase family

Top 10 interactors (score): MNN2 (0.824); KRE2 (0.712); YND1 (0.699); VRG4 (0.697); MUB1 (0.662); ZRG8 (0.66); ERG28 (0.63); KRE1 (0.612); NPP2 (0.61); ARL1 (0.606); GCD11 (0.606); HHY1 (0.574); YEA4 (0.56); IKI3 (0.553); ERG4 (0.537); ARB1 (0.529); YCR007C (0.527); YEF1 (0.525); MNN1 (0.52); GPI13 (0.506)

Homologues (species, bitscore): ENTPD6 (Homo sapiens, 184.5); Entpd6 (Mus musculus, 180.3); entpd6 (Danio rerio, 181.8); entpd6 (Xenopus tropicalis, 175.6); NTPase (Drosophila melanogaster, 159.8); uda-1 (Caenorhabditis elegans, 166.4); APY1 (Arabidopsis thaliana, 146.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:67836-69392:+ gene-YEL042W_AKU4011 rna-NM_001178857.1_AKU4011 cds-NP_010872.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000075.1:11157-12713:- gene-YEL042W_BG1 rna-NM_001178857.1_BG1 cds-NP_010872.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:71976-73532:+ gene-YEL042W_Bruggeman rna-NM_001178857.1_Bruggeman cds-NP_010872.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:69766-71322:+ gene-YEL042W_CAT1 rna-NM_001178857.1_CAT1 cds-NP_010872.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:67781-69337:+ gene-YEL042W_CBS1585 rna-NM_001178857.1_CBS1585 cds-NP_010872.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:69409-70965:+ gene-YEL042W_CBS436 rna-NM_001178857.1_CBS436 cds-NP_010872.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:68033-69589:+ gene-YEL042W_CBS6412 rna-NM_001178857.1_CBS6412 cds-NP_010872.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:72673-74229:+ gene-YEL042W_CBS6413 rna-NM_001178857.1_CBS6413 cds-NP_010872.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:71624-73180:+ gene-YEL042W_CENPK1137D rna-NM_001178857.1_CENPK1137D cds-NP_010872.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:67587-69143:+ gene-YEL042W_EthanolRed rna-NM_001178857.1_EthanolRed cds-NP_010872.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:67850-69406:+ gene-YEL042W_FaliES1 rna-NM_001178857.1_FaliES1 cds-NP_010872.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000022.1:10408-11964:- gene-YEL042W_JAY291 rna-NM_001178857.1_JAY291 cds-NP_010872.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:72034-73590:+ gene-YEL042W_MUCL30387 rna-NM_001178857.1_MUCL30387 cds-NP_010872.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:67891-69447:+ gene-YEL042W_MUCL30388 rna-NM_001178857.1_MUCL30388 cds-NP_010872.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:67150-68706:+ gene-YEL042W_MUCL39482 rna-NM_001178857.1_MUCL39482 cds-NP_010872.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:71783-73339:+ gene-YEL042W_MUCL42920 rna-NM_001178857.1_MUCL42920 cds-NP_010872.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:73770-75326:+ gene-YEL042W_NCIM3186 rna-NM_001178857.1_NCIM3186 cds-NP_010872.1_NCIM3186 99.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:72244-73800:+ gene-YEL042W_NCYC1407 rna-NM_001178857.1_NCYC1407 cds-NP_010872.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:76269-77825:+ gene-YEL042W_PE2H3 rna-NM_001178857.1_PE2H3 cds-NP_010872.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:72184-73740:+ gene-YEL042W_PE2H4 rna-NM_001178857.1_PE2H4 cds-NP_010872.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:73771-75327:+ gene-YEL042W_S288C rna-NM_001178857.1_S288C cds-NP_010872.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000053.1:11244-12800:- gene-YEL042W_SA1 rna-NM_001178857.1_SA1 cds-NP_010872.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:68249-69805:+ gene-YEL042W_ThermosaccDry rna-NM_001178857.1_ThermosaccDry cds-NP_010872.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:67472-69028:+ gene-YEL042W_VR1 rna-NM_001178857.1_VR1 cds-NP_010872.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:67182-68738:+ gene-YEL042W_ZTW1 rna-NM_001178857.1_ZTW1 cds-NP_010872.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:69832-71387:+ gene-YEL042W_Sparadoxus rna-NM_001178857.1_Sparadoxus cds-NP_010872.1_Sparadoxus 89.0 99.9 Verified 1 1 0 False False False True False

Additional files