Gene name: GCY1
Reference locus (S288C): YOR120W
Gene biotype: protein_coding
Description: Glycerol 2-dehydrogenase (NADP(+)); Glycerol dehydrogenase; involved in an alternative pathway for glycerol catabolism used under microaerobic conditions; also has mRNA binding activity; member of the aldo-keto reductase (AKR) family; human homolog AKR1B1 can complement yeast null mutant; protein abundance increases in response to DNA replication stress; GCY1 has a paralog, YPR1, that arose from the whole genome duplication
Top 10 interactors (score): DAK1 (0.995); DAK2 (0.989); GPP2 (0.979); PGM2 (0.975); GUT1 (0.975); GPP1 (0.973); DCS2 (0.964); GOR1 (0.944); GAD1 (0.943); MSC1 (0.935); SOL4 (0.933); TFS1 (0.923); ADH7 (0.915); ADH6 (0.915); YJU3 (0.901); OM45 (0.895); STF2 (0.891); ALD3 (0.884); NQM1 (0.868); RTC3 (0.864)
Homologues (species, bitscore): AKR1A1 (Homo sapiens, 228.0); Akr1a1 (Mus musculus, 227.6); akr1b1 (Danio rerio, 236.1); akr1a1 (Xenopus tropicalis, 228.8); CG12766 (Drosophila melanogaster, 216.5); Y39G8B.1 (Caenorhabditis elegans, 199.9); ChlAKR (Arabidopsis thaliana, 228.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:535178-536116:+ | gene-YOR120W_AKU4011 | rna-NM_001183539.1_AKU4011 | cds-NP_014763.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:43155-44093:- | gene-YOR120W_BG1 | rna-NM_001183539.1_BG1 | cds-NP_014763.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:538726-539664:+ | gene-YOR120W_Bruggeman | rna-NM_001183539.1_Bruggeman | cds-NP_014763.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:538731-539669:+ | gene-YOR120W_CAT1 | rna-NM_001183539.1_CAT1 | cds-NP_014763.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:530740-531678:+ | gene-YOR120W_CBS1585 | rna-NM_001183539.1_CBS1585 | cds-NP_014763.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:535451-536389:+ | gene-YOR120W_CBS436 | rna-NM_001183539.1_CBS436 | cds-NP_014763.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:529226-530164:+ | gene-YOR120W_CBS6412 | rna-NM_001183539.1_CBS6412 | cds-NP_014763.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:536522-537460:+ | gene-YOR120W_CBS6413 | rna-NM_001183539.1_CBS6413 | cds-NP_014763.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:551191-552129:+ | gene-YOR120W_CENPK1137D | rna-NM_001183539.1_CENPK1137D | cds-NP_014763.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:531546-532484:+ | gene-YOR120W_EthanolRed | rna-NM_001183539.1_EthanolRed | cds-NP_014763.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:535242-536180:+ | gene-YOR120W_FaliES1 | rna-NM_001183539.1_FaliES1 | cds-NP_014763.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000063.1:23086-24024:- | gene-YOR120W_JAY291 | rna-NM_001183539.1_JAY291 | cds-NP_014763.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:543284-544222:+ | gene-YOR120W_MUCL30387 | rna-NM_001183539.1_MUCL30387 | cds-NP_014763.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:548491-549429:+ | gene-YOR120W_MUCL30388 | rna-NM_001183539.1_MUCL30388 | cds-NP_014763.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:538135-539073:+ | gene-YOR120W_MUCL39482 | rna-NM_001183539.1_MUCL39482 | cds-NP_014763.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:554180-555118:+ | gene-YOR120W_MUCL42920 | rna-NM_001183539.1_MUCL42920 | cds-NP_014763.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:551003-551941:+ | gene-YOR120W_NCIM3186 | rna-NM_001183539.1_NCIM3186 | cds-NP_014763.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:544582-545520:+ | gene-YOR120W_NCYC1407 | rna-NM_001183539.1_NCYC1407 | cds-NP_014763.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:543585-544523:+ | gene-YOR120W_PE2H3 | rna-NM_001183539.1_PE2H3 | cds-NP_014763.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:553962-554900:+ | gene-YOR120W_PE2H4 | rna-NM_001183539.1_PE2H4 | cds-NP_014763.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:551114-552052:+ | gene-YOR120W_S288C | rna-NM_001183539.1_S288C | cds-NP_014763.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:80653-81591:+ | gene-YOR120W_SA1 | rna-NM_001183539.1_SA1 | cds-NP_014763.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:534425-535363:+ | gene-YOR120W_ThermosaccDry | rna-NM_001183539.1_ThermosaccDry | cds-NP_014763.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:536530-537468:+ | gene-YOR120W_VR1 | rna-NM_001183539.1_VR1 | cds-NP_014763.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:268362-269300:+ | gene-YOR120W_ZTW1 | rna-NM_001183539.1_ZTW1 | cds-NP_014763.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:540394-541332:+ | gene-YOR120W_Sparadoxus | rna-NM_001183539.1_Sparadoxus | cds-NP_014763.1_Sparadoxus | 88.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |