GCV3 (YAL044C)


Gene profile

Gene name: GCV3
Reference locus (S288C): YAL044C
Gene biotype: protein_coding

Description: H subunit of the mitochondrial glycine decarboxylase complex; glycine decarboxylase is required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF; Belongs to the GcvH family

Top 10 interactors (score): GCV1 (0.999); GCV2 (0.999); LIP2 (0.998); AIM22 (0.998); LPD1 (0.997); SHM2 (0.996); KGD2 (0.995); LIP5 (0.991); LAT1 (0.985); MTD1 (0.985); AGX1 (0.975); SHM1 (0.974); DFR1 (0.971); MET12 (0.97); MET13 (0.968); PDA1 (0.922); KGD1 (0.917); ACP1 (0.915); PDB1 (0.909); FAU1 (0.904)

Homologues (species, bitscore): GCSH (Homo sapiens, 112.8); Gcsh (Mus musculus, 114.4); gcsha (Danio rerio, 112.8); gcsh (Xenopus tropicalis, 108.2); ppl (Drosophila melanogaster, 111.3); gcsh-1 (Caenorhabditis elegans, 118.2); AT2G35120 (Arabidopsis thaliana, 111.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005295.1:43095-43607:- gene-YAL044C_AKU4011 rna-NM_001178189.1_AKU4011 cds-NP_009355.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000070.1:30164-30676:- gene-YAL044C_BG1 rna-NM_001178189.1_BG1 cds-NP_009355.3_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005503.1:57553-58065:- gene-YAL044C_Bruggeman rna-NM_001178189.1_Bruggeman cds-NP_009355.3_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005519.1:44313-44825:- gene-YAL044C_CAT1 rna-NM_001178189.1_CAT1 cds-NP_009355.3_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005359.1:56116-56628:- gene-YAL044C_CBS1585 rna-NM_001178189.1_CBS1585 cds-NP_009355.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005343.1:56359-56871:- gene-YAL044C_CBS436 rna-NM_001178189.1_CBS436 cds-NP_009355.3_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005327.1:42261-42773:- gene-YAL044C_CBS6412 rna-NM_001178189.1_CBS6412 cds-NP_009355.3_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005311.1:54379-54891:- gene-YAL044C_CBS6413 rna-NM_001178189.1_CBS6413 cds-NP_009355.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001522.1:58006-58518:- gene-YAL044C_CENPK1137D rna-NM_001178189.1_CENPK1137D cds-NP_009355.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005471.1:44509-45021:- gene-YAL044C_EthanolRed rna-NM_001178189.1_EthanolRed cds-NP_009355.3_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005535.1:58451-58963:- gene-YAL044C_FaliES1 rna-NM_001178189.1_FaliES1 cds-NP_009355.3_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000084.1:30403-30915:- gene-YAL044C_JAY291 rna-NM_001178189.1_JAY291 cds-NP_009355.3_JAY291 99.2 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005407.1:59057-59569:- gene-YAL044C_MUCL30387 rna-NM_001178189.1_MUCL30387 cds-NP_009355.3_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005439.1:55604-56116:- gene-YAL044C_MUCL30388 rna-NM_001178189.1_MUCL30388 cds-NP_009355.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005279.1:54920-55432:- gene-YAL044C_MUCL39482 rna-NM_001178189.1_MUCL39482 cds-NP_009355.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005423.1:57262-57774:- gene-YAL044C_MUCL42920 rna-NM_001178189.1_MUCL42920 cds-NP_009355.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011810.1:57827-58339:- gene-YAL044C_NCIM3186 rna-NM_001178189.1_NCIM3186 cds-NP_009355.3_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005263.1:42785-43297:- gene-YAL044C_NCYC1407 rna-NM_001178189.1_NCYC1407 cds-NP_009355.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994140.1:44667-45179:- gene-YAL044C_PE2H3 rna-NM_001178189.1_PE2H3 cds-NP_009355.3_PE2H3 99.2 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999872.1:44386-44898:- gene-YAL044C_PE2H4 rna-NM_001178189.1_PE2H4 cds-NP_009355.3_PE2H4 99.2 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001133.9:57950-58462:- gene-YAL044C_S288C rna-NM_001178189.1_S288C cds-NP_009355.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000084.1:32560-33072:- gene-YAL044C_SA1 rna-NM_001178189.1_SA1 cds-NP_009355.3_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005487.1:58661-59173:- gene-YAL044C_ThermosaccDry rna-NM_001178189.1_ThermosaccDry cds-NP_009355.3_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005455.1:59926-60438:- gene-YAL044C_VR1 rna-NM_001178189.1_VR1 cds-NP_009355.3_VR1 99.4 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000002.1:30470-30982:- gene-YAL044C_ZTW1 rna-NM_001178189.1_ZTW1 cds-NP_009355.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047487.1:48150-48662:- gene-YAL044C_Sparadoxus rna-NM_001178189.1_Sparadoxus cds-NP_009355.3_Sparadoxus 93.3 100.0 Verified 1 1 1 False True False False False

Additional files