Gene name: GCV2
Reference locus (S288C): YMR189W
Gene biotype: protein_coding
Description: P subunit of the mitochondrial glycine decarboxylase complex; glycine decarboxylase is required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm
Top 10 interactors (score): GCV1 (0.999); GCV3 (0.999); SHM2 (0.999); LPD1 (0.996); MTD1 (0.992); SHM1 (0.986); MET13 (0.979); DFR1 (0.978); MET12 (0.976); AGX1 (0.973); GLY1 (0.97); GLT1 (0.968); GLN1 (0.944); HEM1 (0.928); ADE17 (0.928); PUT2 (0.905); GDH3 (0.888); ARG5,6 (0.887); GDH2 (0.856); GDH1 (0.841)
Homologues (species, bitscore): GLDC (Homo sapiens, 1030.8); Gldc (Mus musculus, 1037.7); GLDC (Danio rerio, 753.8); gldc (Xenopus tropicalis, 964.5); CG3999 (Drosophila melanogaster, 1005.0); R12C12.1 (Caenorhabditis elegans, 935.3); GLDP2 (Arabidopsis thaliana, 1043.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:677432-680536:+ | gene-YMR189W_AKU4011 | rna-NM_001182695.1_AKU4011 | cds-NP_013914.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:274046-277150:- | gene-YMR189W_BG1 | rna-NM_001182695.1_BG1 | cds-NP_013914.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:621662-624766:+ | gene-YMR189W_Bruggeman | rna-NM_001182695.1_Bruggeman | cds-NP_013914.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:624905-628009:+ | gene-YMR189W_CAT1 | rna-NM_001182695.1_CAT1 | cds-NP_013914.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:609688-612792:+ | gene-YMR189W_CBS1585 | rna-NM_001182695.1_CBS1585 | cds-NP_013914.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:613951-617055:+ | gene-YMR189W_CBS436 | rna-NM_001182695.1_CBS436 | cds-NP_013914.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:721247-724351:+ | gene-YMR189W_CBS6412 | rna-NM_001182695.1_CBS6412 | cds-NP_013914.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:608837-611941:+ | gene-YMR189W_CBS6413 | rna-NM_001182695.1_CBS6413 | cds-NP_013914.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:632113-635217:+ | gene-YMR189W_CENPK1137D | rna-NM_001182695.1_CENPK1137D | cds-NP_013914.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:669877-672981:+ | gene-YMR189W_EthanolRed | rna-NM_001182695.1_EthanolRed | cds-NP_013914.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:615533-618637:+ | gene-YMR189W_FaliES1 | rna-NM_001182695.1_FaliES1 | cds-NP_013914.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:167370-170474:- | gene-YMR189W_JAY291 | rna-NM_001182695.1_JAY291 | cds-NP_013914.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:615208-618312:+ | gene-YMR189W_MUCL30387 | rna-NM_001182695.1_MUCL30387 | cds-NP_013914.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:621988-625092:+ | gene-YMR189W_MUCL30388 | rna-NM_001182695.1_MUCL30388 | cds-NP_013914.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:610760-613864:+ | gene-YMR189W_MUCL39482 | rna-NM_001182695.1_MUCL39482 | cds-NP_013914.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:618107-621211:+ | gene-YMR189W_MUCL42920 | rna-NM_001182695.1_MUCL42920 | cds-NP_013914.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:637454-640558:+ | gene-YMR189W_NCIM3186 | rna-NM_001182695.1_NCIM3186 | cds-NP_013914.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:610412-613516:+ | gene-YMR189W_NCYC1407 | rna-NM_001182695.1_NCYC1407 | cds-NP_013914.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:620295-623399:+ | gene-YMR189W_PE2H3 | rna-NM_001182695.1_PE2H3 | cds-NP_013914.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:621281-624385:+ | gene-YMR189W_PE2H4 | rna-NM_001182695.1_PE2H4 | cds-NP_013914.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:637500-640604:+ | gene-YMR189W_S288C | rna-NM_001182695.1_S288C | cds-NP_013914.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:167496-170600:- | gene-YMR189W_SA1 | rna-NM_001182695.1_SA1 | cds-NP_013914.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:611659-614763:+ | gene-YMR189W_ThermosaccDry | rna-NM_001182695.1_ThermosaccDry | cds-NP_013914.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:624828-627932:+ | gene-YMR189W_VR1 | rna-NM_001182695.1_VR1 | cds-NP_013914.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:27447-30551:+ | gene-YMR189W_ZTW1 | rna-NM_001182695.1_ZTW1 | cds-NP_013914.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:629551-632655:+ | gene-YMR189W_Sparadoxus | rna-NM_001182695.1_Sparadoxus | cds-NP_013914.1_Sparadoxus | 90.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |