GCV1 (YDR019C)


Gene profile

Gene name: GCV1
Reference locus (S288C): YDR019C
Gene biotype: protein_coding

Description: T subunit of the mitochondrial glycine decarboxylase complex; glycine decarboxylase is required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm

Top 10 interactors (score): GCV3 (0.999); SHM2 (0.999); GCV2 (0.999); MTD1 (0.998); SHM1 (0.998); LPD1 (0.997); ADE17 (0.994); MIS1 (0.991); MET13 (0.985); ADE3 (0.985); AGX1 (0.984); ADE16 (0.979); ADE8 (0.978); MET12 (0.978); DFR1 (0.978); CDC21 (0.97); GLT1 (0.959); FMT1 (0.951); GDH3 (0.949); GDH1 (0.939)

Homologues (species, bitscore): AMT (Homo sapiens, 270.8); Amt (Mus musculus, 273.9); amt (Danio rerio, 288.5); amt (Xenopus tropicalis, 266.5); CG6415 (Drosophila melanogaster, 275.0); gcst-1 (Caenorhabditis elegans, 261.2); AT1G11860 (Arabidopsis thaliana, 285.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:470090-471292:- gene-YDR019C_AKU4011 rna-NM_001180327.1_AKU4011 cds-NP_010302.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:78504-79706:+ gene-YDR019C_BG1 rna-NM_001180327.1_BG1 cds-NP_010302.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:498332-499534:- gene-YDR019C_Bruggeman rna-NM_001180327.1_Bruggeman cds-NP_010302.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:483399-484601:- gene-YDR019C_CAT1 rna-NM_001180327.1_CAT1 cds-NP_010302.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:466681-467883:- gene-YDR019C_CBS1585 rna-NM_001180327.1_CBS1585 cds-NP_010302.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:483664-484866:- gene-YDR019C_CBS436 rna-NM_001180327.1_CBS436 cds-NP_010302.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:463591-464793:- gene-YDR019C_CBS6412 rna-NM_001180327.1_CBS6412 cds-NP_010302.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:485870-487072:- gene-YDR019C_CBS6413 rna-NM_001180327.1_CBS6413 cds-NP_010302.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:483128-484330:- gene-YDR019C_CENPK1137D rna-NM_001180327.1_CENPK1137D cds-NP_010302.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:478112-479314:- gene-YDR019C_EthanolRed rna-NM_001180327.1_EthanolRed cds-NP_010302.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:484471-485673:- gene-YDR019C_FaliES1 rna-NM_001180327.1_FaliES1 cds-NP_010302.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000042.1:27922-29124:+ gene-YDR019C_JAY291 rna-NM_001180327.1_JAY291 cds-NP_010302.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:483912-485114:- gene-YDR019C_MUCL30387 rna-NM_001180327.1_MUCL30387 cds-NP_010302.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:474374-475576:- gene-YDR019C_MUCL30388 rna-NM_001180327.1_MUCL30388 cds-NP_010302.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:468049-469251:- gene-YDR019C_MUCL39482 rna-NM_001180327.1_MUCL39482 cds-NP_010302.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:389701-390903:- gene-YDR019C_MUCL42920 rna-NM_001180327.1_MUCL42920 cds-NP_010302.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:484086-485288:- gene-YDR019C_NCIM3186 rna-NM_001180327.1_NCIM3186 cds-NP_010302.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:467482-468684:- gene-YDR019C_NCYC1407 rna-NM_001180327.1_NCYC1407 cds-NP_010302.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:482568-483770:- gene-YDR019C_PE2H3 rna-NM_001180327.1_PE2H3 cds-NP_010302.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:481873-483075:- gene-YDR019C_PE2H4 rna-NM_001180327.1_PE2H4 cds-NP_010302.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:484163-485365:- gene-YDR019C_S288C rna-NM_001180327.1_S288C cds-NP_010302.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000065.1:11333-12535:- gene-YDR019C_SA1 rna-NM_001180327.1_SA1 cds-NP_010302.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:483950-485152:- gene-YDR019C_ThermosaccDry rna-NM_001180327.1_ThermosaccDry cds-NP_010302.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:488519-489721:- gene-YDR019C_VR1 rna-NM_001180327.1_VR1 cds-NP_010302.1_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:481844-483046:- gene-YDR019C_ZTW1 rna-NM_001180327.1_ZTW1 cds-NP_010302.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:485615-486814:- gene-YDR019C_Sparadoxus rna-NM_001180327.1_Sparadoxus cds-NP_010302.1_Sparadoxus 90.1 99.7 Verified 1 1 1 False True False False False

Additional files