Gene name: GCS1
Reference locus (S288C): YDL226C
Gene biotype: protein_coding
Description: ADP-ribosylation factor GTPase activating protein (ARF GAP); involved in ER-Golgi transport; required for prospore membrane formation; regulates phospholipase Spo14p; shares functional similarity with Glo3p; GCS1 has a paralog, SPS18, that arose from the whole genome duplication
Top 10 interactors (score): ARF1 (0.997); GLO3 (0.994); ARF2 (0.987); ARL1 (0.981); ARF3 (0.948); GEA1 (0.913); GEA2 (0.913); SEC21 (0.883); AGE2 (0.881); SNC1 (0.871); COP1 (0.87); YPT31 (0.856); ERD2 (0.852); SEC22 (0.841); YIP1 (0.839); RET2 (0.836); SEC7 (0.827); SEC14 (0.817); SNC2 (0.815); SPO14 (0.808)
Homologues (species, bitscore): ARFGAP1 (Homo sapiens, 127.1); Arfgap1 (Mus musculus, 134.8); ARFGAP1 (Danio rerio, 104.0); arfgap1 (Xenopus tropicalis, 108.2); ArfGAP1 (Drosophila melanogaster, 154.1); K02B12.7 (Caenorhabditis elegans, 132.5); AGD6 (Arabidopsis thaliana, 150.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:34610-35668:- | gene-YDL226C_AKU4011 | rna-NM_001180286.1_AKU4011 | cds-NP_010055.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000077.1:31434-32492:+ | gene-YDL226C_BG1 | rna-NM_001180286.1_BG1 | cds-NP_010055.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:50292-51350:- | gene-YDL226C_Bruggeman | rna-NM_001180286.1_Bruggeman | cds-NP_010055.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:270089-271147:- | gene-YDL226C_CAT1 | rna-NM_001180286.1_CAT1 | cds-NP_010055.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:33485-34543:- | gene-YDL226C_CBS1585 | rna-NM_001180286.1_CBS1585 | cds-NP_010055.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:248364-249422:- | gene-YDL226C_CBS436 | rna-NM_001180286.1_CBS436 | cds-NP_010055.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:33597-34655:- | gene-YDL226C_CBS6412 | rna-NM_001180286.1_CBS6412 | cds-NP_010055.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:51120-52178:- | gene-YDL226C_CBS6413 | rna-NM_001180286.1_CBS6413 | cds-NP_010055.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:49781-50839:- | gene-YDL226C_CENPK1137D | rna-NM_001180286.1_CENPK1137D | cds-NP_010055.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:47054-48112:- | gene-YDL226C_EthanolRed | rna-NM_001180286.1_EthanolRed | cds-NP_010055.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:51381-52439:- | gene-YDL226C_FaliES1 | rna-NM_001180286.1_FaliES1 | cds-NP_010055.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000213.1:5708-6766:- | gene-YDL226C_JAY291 | rna-NM_001180286.1_JAY291 | cds-NP_010055.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:49232-50290:- | gene-YDL226C_MUCL30387 | rna-NM_001180286.1_MUCL30387 | cds-NP_010055.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:257050-258108:- | gene-YDL226C_MUCL30388 | rna-NM_001180286.1_MUCL30388 | cds-NP_010055.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:34328-35386:- | gene-YDL226C_MUCL39482 | rna-NM_001180286.1_MUCL39482 | cds-NP_010055.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:50377-51435:- | gene-YDL226C_MUCL42920 | rna-NM_001180286.1_MUCL42920 | cds-NP_010055.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:51038-52096:- | gene-YDL226C_NCIM3186 | rna-NM_001180286.1_NCIM3186 | cds-NP_010055.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:34285-35343:- | gene-YDL226C_NCYC1407 | rna-NM_001180286.1_NCYC1407 | cds-NP_010055.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:41321-42379:- | gene-YDL226C_PE2H3 | rna-NM_001180286.1_PE2H3 | cds-NP_010055.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:41331-42389:- | gene-YDL226C_PE2H4 | rna-NM_001180286.1_PE2H4 | cds-NP_010055.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:51115-52173:- | gene-YDL226C_S288C | rna-NM_001180286.1_S288C | cds-NP_010055.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000094.1:5514-6572:- | gene-YDL226C_SA1 | rna-NM_001180286.1_SA1 | cds-NP_010055.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:51136-52194:- | gene-YDL226C_ThermosaccDry | rna-NM_001180286.1_ThermosaccDry | cds-NP_010055.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:51308-52366:- | gene-YDL226C_VR1 | rna-NM_001180286.1_VR1 | cds-NP_010055.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:50302-51360:- | gene-YDL226C_ZTW1 | rna-NM_001180286.1_ZTW1 | cds-NP_010055.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:53719-54777:- | gene-YDL226C_Sparadoxus | rna-NM_001180286.1_Sparadoxus | cds-NP_010055.1_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |