Gene name: GCN1
Reference locus (S288C): YGL195W
Gene biotype: protein_coding
Description: eIF-2-alpha kinase activator GCN1; Positive regulator of the Gcn2p kinase activity; forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA; Belongs to the GCN1 family
Top 10 interactors (score): GCN20 (0.999); GCN2 (0.999); RBG2 (0.976); CUS1 (0.968); GIR2 (0.967); CEF1 (0.967); DYN1 (0.967); HSH155 (0.965); SMD2 (0.962); SMD1 (0.962); YNR048W (0.918); CYM1 (0.903); YIH1 (0.903); HTS1 (0.903); GCN3 (0.894); GFA1 (0.889); TOP2 (0.867); RPA190 (0.824); SSA1 (0.818); TMA46 (0.816)
Homologues (species, bitscore): GCN1L1 (Homo sapiens, 1023.8); Gcn1l1 (Mus musculus, 1026.5); gcn1l1 (Danio rerio, 1011.1); gcn1l1 (Xenopus tropicalis, 984.2); CG17514 (Drosophila melanogaster, 970.3); gcn-1 (Caenorhabditis elegans, 723.0); ILA (Arabidopsis thaliana, 939.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:134062-142080:+ | gene-YGL195W_AKU4011 | rna-NM_001181060.3_AKU4011 | cds-NP_011320.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:268341-276359:- | gene-YGL195W_BG1 | rna-NM_001181060.3_BG1 | cds-NP_011320.3_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:136282-144300:+ | gene-YGL195W_Bruggeman | rna-NM_001181060.3_Bruggeman | cds-NP_011320.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:131918-139936:+ | gene-YGL195W_CAT1 | rna-NM_001181060.3_CAT1 | cds-NP_011320.3_CAT1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:137207-145225:+ | gene-YGL195W_CBS1585 | rna-NM_001181060.3_CBS1585 | cds-NP_011320.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:132181-140199:+ | gene-YGL195W_CBS436 | rna-NM_001181060.3_CBS436 | cds-NP_011320.3_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:123977-131995:+ | gene-YGL195W_CBS6412 | rna-NM_001181060.3_CBS6412 | cds-NP_011320.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:131512-139530:+ | gene-YGL195W_CBS6413 | rna-NM_001181060.3_CBS6413 | cds-NP_011320.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:131704-139722:+ | gene-YGL195W_CENPK1137D | rna-NM_001181060.3_CENPK1137D | cds-NP_011320.3_CENPK1137D | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:124044-132062:+ | gene-YGL195W_EthanolRed | rna-NM_001181060.3_EthanolRed | cds-NP_011320.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:125046-133064:+ | gene-YGL195W_FaliES1 | rna-NM_001181060.3_FaliES1 | cds-NP_011320.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000397.1:50358-58376:+ | gene-YGL195W_JAY291 | rna-NM_001181060.3_JAY291 | cds-NP_011320.3_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:133540-141558:+ | gene-YGL195W_MUCL30387 | rna-NM_001181060.3_MUCL30387 | cds-NP_011320.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:135879-143897:+ | gene-YGL195W_MUCL30388 | rna-NM_001181060.3_MUCL30388 | cds-NP_011320.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:134208-142226:+ | gene-YGL195W_MUCL39482 | rna-NM_001181060.3_MUCL39482 | cds-NP_011320.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:136822-144840:+ | gene-YGL195W_MUCL42920 | rna-NM_001181060.3_MUCL42920 | cds-NP_011320.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:131525-139543:+ | gene-YGL195W_NCIM3186 | rna-NM_001181060.3_NCIM3186 | cds-NP_011320.3_NCIM3186 | 97.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:125692-133710:+ | gene-YGL195W_NCYC1407 | rna-NM_001181060.3_NCYC1407 | cds-NP_011320.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:127686-135704:+ | gene-YGL195W_PE2H3 | rna-NM_001181060.3_PE2H3 | cds-NP_011320.3_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:127234-135252:+ | gene-YGL195W_PE2H4 | rna-NM_001181060.3_PE2H4 | cds-NP_011320.3_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:131525-139543:+ | gene-YGL195W_S288C | rna-NM_001181060.3_S288C | cds-NP_011320.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:235962-243980:- | gene-YGL195W_SA1 | rna-NM_001181060.3_SA1 | cds-NP_011320.3_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:125306-133324:+ | gene-YGL195W_ThermosaccDry | rna-NM_001181060.3_ThermosaccDry | cds-NP_011320.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:132593-140611:+ | gene-YGL195W_VR1 | rna-NM_001181060.3_VR1 | cds-NP_011320.3_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:123842-131860:+ | gene-YGL195W_ZTW1 | rna-NM_001181060.3_ZTW1 | cds-NP_011320.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:130724-138742:+ | gene-YGL195W_Sparadoxus | rna-NM_001181060.3_Sparadoxus | cds-NP_011320.3_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |