Gene name: GCD2
Reference locus (S288C): YGR083C
Gene biotype: protein_coding
Description: Delta subunit of the translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; Belongs to the eIF-2B alpha/beta/delta subunits family
Top 10 interactors (score): GCD11 (0.999); SUI2 (0.999); GCD7 (0.999); GCD1 (0.999); GCD6 (0.999); GCN3 (0.999); SUI3 (0.998); GCN2 (0.95); PSA1 (0.907); RGP1 (0.9); RIC1 (0.9); GLT1 (0.88); URA7 (0.877); UTP7 (0.862); TIF5 (0.802); URA8 (0.794); GCN1 (0.79); SUI1 (0.783); ASN1 (0.78); IST1 (0.771)
Homologues (species, bitscore): EIF2B4 (Homo sapiens, 237.3); Eif2b4 (Mus musculus, 250.4); eif2b4 (Danio rerio, 246.9); eif2b4 (Xenopus tropicalis, 214.5); CG10315 (Drosophila melanogaster, 214.9); F11A3.2 (Caenorhabditis elegans, 66.6); AT5G38640 (Arabidopsis thaliana, 256.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:628537-630492:- | gene-YGR083C_AKU4011 | rna-NM_001181212.1_AKU4011 | cds-NP_011597.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:64837-66792:- | gene-YGR083C_BG1 | rna-NM_001181212.1_BG1 | cds-NP_011597.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:630812-632767:- | gene-YGR083C_Bruggeman | rna-NM_001181212.1_Bruggeman | cds-NP_011597.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:629250-631205:- | gene-YGR083C_CAT1 | rna-NM_001181212.1_CAT1 | cds-NP_011597.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:629830-631785:- | gene-YGR083C_CBS1585 | rna-NM_001181212.1_CBS1585 | cds-NP_011597.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:631167-633122:- | gene-YGR083C_CBS436 | rna-NM_001181212.1_CBS436 | cds-NP_011597.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | MBVQ01000080.1:1891-3846:+ | gene-YGR083C_CBS6412 | rna-NM_001181212.1_CBS6412 | cds-NP_011597.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:626466-628421:- | gene-YGR083C_CBS6413 | rna-NM_001181212.1_CBS6413 | cds-NP_011597.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:644533-646488:- | gene-YGR083C_CENPK1137D | rna-NM_001181212.1_CENPK1137D | cds-NP_011597.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:616798-618753:- | gene-YGR083C_EthanolRed | rna-NM_001181212.1_EthanolRed | cds-NP_011597.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:620255-622210:- | gene-YGR083C_FaliES1 | rna-NM_001181212.1_FaliES1 | cds-NP_011597.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000435.1:71203-73158:- | gene-YGR083C_JAY291 | rna-NM_001181212.1_JAY291 | cds-NP_011597.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:627521-629476:- | gene-YGR083C_MUCL30387 | rna-NM_001181212.1_MUCL30387 | cds-NP_011597.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:630856-632811:- | gene-YGR083C_MUCL30388 | rna-NM_001181212.1_MUCL30388 | cds-NP_011597.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:625726-627681:- | gene-YGR083C_MUCL39482 | rna-NM_001181212.1_MUCL39482 | cds-NP_011597.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:635489-637444:- | gene-YGR083C_MUCL42920 | rna-NM_001181212.1_MUCL42920 | cds-NP_011597.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:644860-646815:- | gene-YGR083C_NCIM3186 | rna-NM_001181212.1_NCIM3186 | cds-NP_011597.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:619917-621872:- | gene-YGR083C_NCYC1407 | rna-NM_001181212.1_NCYC1407 | cds-NP_011597.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:623107-625062:- | gene-YGR083C_PE2H3 | rna-NM_001181212.1_PE2H3 | cds-NP_011597.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:628227-630182:- | gene-YGR083C_PE2H4 | rna-NM_001181212.1_PE2H4 | cds-NP_011597.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:644860-646815:- | gene-YGR083C_S288C | rna-NM_001181212.1_S288C | cds-NP_011597.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:71431-73386:- | gene-YGR083C_SA1 | rna-NM_001181212.1_SA1 | cds-NP_011597.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:639599-641554:- | gene-YGR083C_ThermosaccDry | rna-NM_001181212.1_ThermosaccDry | cds-NP_011597.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:736552-738507:- | gene-YGR083C_VR1 | rna-NM_001181212.1_VR1 | cds-NP_011597.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:95051-97007:- | gene-YGR083C_ZTW1 | rna-NM_001181212.1_ZTW1 | cds-NP_011597.1_ZTW1 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:630145-632103:- | gene-YGR083C_Sparadoxus | rna-NM_001181212.1_Sparadoxus | cds-NP_011597.1_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |