Gene name: GCD14
Reference locus (S288C): YJL125C
Gene biotype: protein_coding
Description: tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61; Subunit of tRNA (1-methyladenosine) methyltransferase; required, along with Gcd10p, for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family
Top 10 interactors (score): TRM82 (0.999); GCD10 (0.999); TRM8 (0.999); TRM11 (0.997); MTQ2 (0.993); SPB1 (0.992); TRM112 (0.989); NCL1 (0.984); BUD23 (0.977); SOF1 (0.976); DUS1 (0.976); DBP8 (0.974); TRM5 (0.972); TRM10 (0.971); KRE33 (0.967); TRM7 (0.964); ENP2 (0.963); NOP2 (0.958); NOP4 (0.958); SDA1 (0.957)
Homologues (species, bitscore): TRMT61A (Homo sapiens, 186.8); Trmt61a (Mus musculus, 187.2); trmt61a (Danio rerio, 194.1); trmt61a (Xenopus tropicalis, 209.1); CG14544 (Drosophila melanogaster, 185.3); W02A11.1 (Caenorhabditis elegans, 171.4); AT5G14600 (Arabidopsis thaliana, 183.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:173848-174999:- | gene-YJL125C_AKU4011 | rna-NM_001181558.1_AKU4011 | cds-NP_012410.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:438744-439895:+ | gene-YJL125C_BG1 | rna-NM_001181558.1_BG1 | cds-NP_012410.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:185887-187038:- | gene-YJL125C_Bruggeman | rna-NM_001181558.1_Bruggeman | cds-NP_012410.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:189697-190848:- | gene-YJL125C_CAT1 | rna-NM_001181558.1_CAT1 | cds-NP_012410.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:179482-180633:- | gene-YJL125C_CBS1585 | rna-NM_001181558.1_CBS1585 | cds-NP_012410.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:204212-205363:- | gene-YJL125C_CBS436 | rna-NM_001181558.1_CBS436 | cds-NP_012410.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:175499-176650:- | gene-YJL125C_CBS6412 | rna-NM_001181558.1_CBS6412 | cds-NP_012410.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:176957-178108:- | gene-YJL125C_CBS6413 | rna-NM_001181558.1_CBS6413 | cds-NP_012410.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:167998-169149:- | gene-YJL125C_CENPK1137D | rna-NM_001181558.1_CENPK1137D | cds-NP_012410.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:177817-178968:- | gene-YJL125C_EthanolRed | rna-NM_001181558.1_EthanolRed | cds-NP_012410.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:183469-184620:- | gene-YJL125C_FaliES1 | rna-NM_001181558.1_FaliES1 | cds-NP_012410.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000099.1:64634-65785:- | gene-YJL125C_JAY291 | rna-NM_001181558.1_JAY291 | cds-NP_012410.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:188155-189306:- | gene-YJL125C_MUCL30387 | rna-NM_001181558.1_MUCL30387 | cds-NP_012410.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:184233-185384:- | gene-YJL125C_MUCL30388 | rna-NM_001181558.1_MUCL30388 | cds-NP_012410.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:178428-179579:- | gene-YJL125C_MUCL39482 | rna-NM_001181558.1_MUCL39482 | cds-NP_012410.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:184221-185372:- | gene-YJL125C_MUCL42920 | rna-NM_001181558.1_MUCL42920 | cds-NP_012410.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:185507-186658:- | gene-YJL125C_NCIM3186 | rna-NM_001181558.1_NCIM3186 | cds-NP_012410.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:176835-177986:- | gene-YJL125C_NCYC1407 | rna-NM_001181558.1_NCYC1407 | cds-NP_012410.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:189614-190765:- | gene-YJL125C_PE2H3 | rna-NM_001181558.1_PE2H3 | cds-NP_012410.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:189258-190409:- | gene-YJL125C_PE2H4 | rna-NM_001181558.1_PE2H4 | cds-NP_012410.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:185528-186679:- | gene-YJL125C_S288C | rna-NM_001181558.1_S288C | cds-NP_012410.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000085.1:12491-13642:+ | gene-YJL125C_SA1 | rna-NM_001181558.1_SA1 | cds-NP_012410.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:176660-177811:- | gene-YJL125C_ThermosaccDry | rna-NM_001181558.1_ThermosaccDry | cds-NP_012410.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:183731-184882:- | gene-YJL125C_VR1 | rna-NM_001181558.1_VR1 | cds-NP_012410.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:163939-165090:- | gene-YJL125C_ZTW1 | rna-NM_001181558.1_ZTW1 | cds-NP_012410.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:189139-190290:- | gene-YJL125C_Sparadoxus | rna-NM_001181558.1_Sparadoxus | cds-NP_012410.1_Sparadoxus | 90.5 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |