Gene name: GCD11
Reference locus (S288C): YER025W
Gene biotype: protein_coding
Description: Gamma subunit of the translation initiation factor eIF2; involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met; mutations in human ortholog cause X-linked intellectual disability (XLID); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily
Top 10 interactors (score): GCD2 (0.999); GCD7 (0.999); PRT1 (0.999); GCD1 (0.999); GCD6 (0.999); TIF34 (0.999); TIF11 (0.999); TIF35 (0.999); SUI1 (0.999); SUI3 (0.999); GCN3 (0.999); SUI2 (0.999); RPG1 (0.999); NIP1 (0.999); TIF5 (0.999); GCN2 (0.998); CDC123 (0.997); RPS3 (0.995); RPS0A (0.994); FUN12 (0.993)
Homologues (species, bitscore): EIF2S3 (Homo sapiens, 689.5); Eif2s3x (Mus musculus, 689.5); eif2s3 (Danio rerio, 685.6); eif2s3 (Xenopus tropicalis, 672.5); eIF-2gamma (Drosophila melanogaster, 680.6); Y39G10AR.8 (Caenorhabditis elegans, 629.4); F20D22.6 (Arabidopsis thaliana, 653.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:199278-200861:+ | gene-YER025W_AKU4011 | rna-NM_001178916.1_AKU4011 | cds-NP_010942.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:225222-226805:- | gene-YER025W_BG1 | rna-NM_001178916.1_BG1 | cds-NP_010942.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:207143-208726:+ | gene-YER025W_Bruggeman | rna-NM_001178916.1_Bruggeman | cds-NP_010942.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:202035-203618:+ | gene-YER025W_CAT1 | rna-NM_001178916.1_CAT1 | cds-NP_010942.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:199201-200784:+ | gene-YER025W_CBS1585 | rna-NM_001178916.1_CBS1585 | cds-NP_010942.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:200792-202375:+ | gene-YER025W_CBS436 | rna-NM_001178916.1_CBS436 | cds-NP_010942.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:199445-201028:+ | gene-YER025W_CBS6412 | rna-NM_001178916.1_CBS6412 | cds-NP_010942.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:204231-205814:+ | gene-YER025W_CBS6413 | rna-NM_001178916.1_CBS6413 | cds-NP_010942.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:203190-204773:+ | gene-YER025W_CENPK1137D | rna-NM_001178916.1_CENPK1137D | cds-NP_010942.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:199909-201492:+ | gene-YER025W_EthanolRed | rna-NM_001178916.1_EthanolRed | cds-NP_010942.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:200174-201757:+ | gene-YER025W_FaliES1 | rna-NM_001178916.1_FaliES1 | cds-NP_010942.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000024.1:66827-68410:+ | gene-YER025W_JAY291 | rna-NM_001178916.1_JAY291 | cds-NP_010942.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:203347-204930:+ | gene-YER025W_MUCL30387 | rna-NM_001178916.1_MUCL30387 | cds-NP_010942.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:199582-201165:+ | gene-YER025W_MUCL30388 | rna-NM_001178916.1_MUCL30388 | cds-NP_010942.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:198245-199828:+ | gene-YER025W_MUCL39482 | rna-NM_001178916.1_MUCL39482 | cds-NP_010942.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:205333-206916:+ | gene-YER025W_MUCL42920 | rna-NM_001178916.1_MUCL42920 | cds-NP_010942.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:205250-206833:+ | gene-YER025W_NCIM3186 | rna-NM_001178916.1_NCIM3186 | cds-NP_010942.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:203316-204899:+ | gene-YER025W_NCYC1407 | rna-NM_001178916.1_NCYC1407 | cds-NP_010942.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:207636-209219:+ | gene-YER025W_PE2H3 | rna-NM_001178916.1_PE2H3 | cds-NP_010942.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:203540-205123:+ | gene-YER025W_PE2H4 | rna-NM_001178916.1_PE2H4 | cds-NP_010942.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:205251-206834:+ | gene-YER025W_S288C | rna-NM_001178916.1_S288C | cds-NP_010942.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000020.1:36848-38431:- | gene-YER025W_SA1 | rna-NM_001178916.1_SA1 | cds-NP_010942.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:200945-202528:+ | gene-YER025W_ThermosaccDry | rna-NM_001178916.1_ThermosaccDry | cds-NP_010942.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:199696-201279:+ | gene-YER025W_VR1 | rna-NM_001178916.1_VR1 | cds-NP_010942.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:198157-199740:+ | gene-YER025W_ZTW1 | rna-NM_001178916.1_ZTW1 | cds-NP_010942.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:201841-203424:+ | gene-YER025W_Sparadoxus | rna-NM_001178916.1_Sparadoxus | cds-NP_010942.1_Sparadoxus | 94.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |