Gene name: GCD1
Reference locus (S288C): YOR260W
Gene biotype: protein_coding
Description: Gamma subunit of the translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; Belongs to the eIF-2B gamma/epsilon subunits family
Top 10 interactors (score): GCD7 (0.999); SUI2 (0.999); GCD2 (0.999); GCD11 (0.999); GCN3 (0.999); SUI3 (0.999); GCD6 (0.999); TIF5 (0.935); GCN2 (0.907); RGP1 (0.901); RIC1 (0.9); YGL230C (0.892); YNL247W (0.853); PRT1 (0.824); GCN4 (0.812); IST1 (0.81); EMC4 (0.783); YGR201C (0.747); TSC13 (0.694); TIF34 (0.692)
Homologues (species, bitscore): EIF2B3 (Homo sapiens, 100.1); Eif2b3 (Mus musculus, 111.7); eif2b3 (Danio rerio, 96.7); eif2b3 (Xenopus tropicalis, 58.2); CG8190 (Drosophila melanogaster, 95.9); ppp-1 (Caenorhabditis elegans, 52.4); AT5G19485 (Arabidopsis thaliana, 99.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:804765-806501:+ | gene-YOR260W_AKU4011 | rna-NM_001183679.1_AKU4011 | cds-NP_014903.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:206793-208529:+ | gene-YOR260W_BG1 | rna-NM_001183679.1_BG1 | cds-NP_014903.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:790218-791954:+ | gene-YOR260W_Bruggeman | rna-NM_001183679.1_Bruggeman | cds-NP_014903.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:790871-792607:+ | gene-YOR260W_CAT1 | rna-NM_001183679.1_CAT1 | cds-NP_014903.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:787748-789484:+ | gene-YOR260W_CBS1585 | rna-NM_001183679.1_CBS1585 | cds-NP_014903.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:786436-788172:+ | gene-YOR260W_CBS436 | rna-NM_001183679.1_CBS436 | cds-NP_014903.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:784668-786269:+ | gene-YOR260W_CBS6412 | rna-NM_001183679.1_CBS6412 | cds-NP_014903.1_CBS6412 | 86.0 | 90.6 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:793510-795246:+ | gene-YOR260W_CBS6413 | rna-NM_001183679.1_CBS6413 | cds-NP_014903.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:813745-815481:+ | gene-YOR260W_CENPK1137D | rna-NM_001183679.1_CENPK1137D | cds-NP_014903.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:780878-782614:+ | gene-YOR260W_EthanolRed | rna-NM_001183679.1_EthanolRed | cds-NP_014903.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:786277-788013:+ | gene-YOR260W_FaliES1 | rna-NM_001183679.1_FaliES1 | cds-NP_014903.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:38823-40559:- | gene-YOR260W_JAY291 | rna-NM_001183679.1_JAY291 | cds-NP_014903.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:794500-796236:+ | gene-YOR260W_MUCL30387 | rna-NM_001183679.1_MUCL30387 | cds-NP_014903.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:801616-803352:+ | gene-YOR260W_MUCL30388 | rna-NM_001183679.1_MUCL30388 | cds-NP_014903.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:795082-796818:+ | gene-YOR260W_MUCL39482 | rna-NM_001183679.1_MUCL39482 | cds-NP_014903.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:804663-806399:+ | gene-YOR260W_MUCL42920 | rna-NM_001183679.1_MUCL42920 | cds-NP_014903.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:813873-815609:+ | gene-YOR260W_NCIM3186 | rna-NM_001183679.1_NCIM3186 | cds-NP_014903.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:795177-796913:+ | gene-YOR260W_NCYC1407 | rna-NM_001183679.1_NCYC1407 | cds-NP_014903.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:794475-796211:+ | gene-YOR260W_PE2H3 | rna-NM_001183679.1_PE2H3 | cds-NP_014903.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:804852-806588:+ | gene-YOR260W_PE2H4 | rna-NM_001183679.1_PE2H4 | cds-NP_014903.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:813984-815720:+ | gene-YOR260W_S288C | rna-NM_001183679.1_S288C | cds-NP_014903.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:223974-225710:+ | gene-YOR260W_SA1 | rna-NM_001183679.1_SA1 | cds-NP_014903.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:785460-787196:+ | gene-YOR260W_ThermosaccDry | rna-NM_001183679.1_ThermosaccDry | cds-NP_014903.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:848915-850651:+ | gene-YOR260W_VR1 | rna-NM_001183679.1_VR1 | cds-NP_014903.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:518380-520117:+ | gene-YOR260W_ZTW1 | rna-NM_001183679.1_ZTW1 | cds-NP_014903.1_ZTW1 | 99.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:791255-792991:+ | gene-YOR260W_Sparadoxus | rna-NM_001183679.1_Sparadoxus | cds-NP_014903.1_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |