Gene name: GBP2
Reference locus (S288C): YCL011C
Gene biotype: protein_coding
Description: Single-strand telomeric DNA-binding protein GBP2; Poly(A+) RNA-binding protein; key surveillance factor for the selective export of spliced mRNAs from the nucleus to the cytoplasm; preference for intron-containing genes; similar to Npl3p; also binds single-stranded telomeric repeat sequence in vitro; relocalizes to the cytosol in response to hypoxia; GBP2 has a paralog, HRB1, that arose from the whole genome duplication
Top 10 interactors (score): NPL3 (0.999); THO2 (0.971); THP2 (0.965); YRA1 (0.964); SUB2 (0.958); HPR1 (0.943); CBC2 (0.892); MEX67 (0.841); NAB2 (0.791); DBP2 (0.781); MFT1 (0.775); HEK2 (0.74); YDR187C (0.718); YIR020C (0.693); YCR022C (0.693); CTK1 (0.692); MSL5 (0.673); TIF4631 (0.658); PIN4 (0.643); PCF11 (0.621)
Homologues (species, bitscore): PABPC1L (Homo sapiens, 94.7); Pabpc1l (Mus musculus, 95.1); pabpc1b (Danio rerio, 85.5); pabpc1 (Xenopus tropicalis, 81.6); pAbp (Drosophila melanogaster, 72.8); Y55F3AM.3 (Caenorhabditis elegans, 86.3); PAB2 (Arabidopsis thaliana, 87.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:96785-98068:- | gene-YCL011C_AKU4011 | rna-NM_001178660.1_AKU4011 | cds-NP_009916.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000178.1:47966-49249:+ | gene-YCL011C_BG1 | rna-NM_001178660.1_BG1 | cds-NP_009916.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:91370-92653:- | gene-YCL011C_Bruggeman | rna-NM_001178660.1_Bruggeman | cds-NP_009916.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:96516-97799:- | gene-YCL011C_CAT1 | rna-NM_001178660.1_CAT1 | cds-NP_009916.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:97434-98717:- | gene-YCL011C_CBS1585 | rna-NM_001178660.1_CBS1585 | cds-NP_009916.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:102351-103634:- | gene-YCL011C_CBS436 | rna-NM_001178660.1_CBS436 | cds-NP_009916.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:84893-86176:- | gene-YCL011C_CBS6412 | rna-NM_001178660.1_CBS6412 | cds-NP_009916.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:96741-98024:- | gene-YCL011C_CBS6413 | rna-NM_001178660.1_CBS6413 | cds-NP_009916.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:101550-102833:- | gene-YCL011C_CENPK1137D | rna-NM_001178660.1_CENPK1137D | cds-NP_009916.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:94803-96086:- | gene-YCL011C_EthanolRed | rna-NM_001178660.1_EthanolRed | cds-NP_009916.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:97096-98379:- | gene-YCL011C_FaliES1 | rna-NM_001178660.1_FaliES1 | cds-NP_009916.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000126.1:11269-12552:- | gene-YCL011C_JAY291 | rna-NM_001178660.1_JAY291 | cds-NP_009916.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:89805-91088:- | gene-YCL011C_MUCL30387 | rna-NM_001178660.1_MUCL30387 | cds-NP_009916.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:89362-90645:- | gene-YCL011C_MUCL30388 | rna-NM_001178660.1_MUCL30388 | cds-NP_009916.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:97851-99134:- | gene-YCL011C_MUCL39482 | rna-NM_001178660.1_MUCL39482 | cds-NP_009916.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:93085-94368:- | gene-YCL011C_MUCL42920 | rna-NM_001178660.1_MUCL42920 | cds-NP_009916.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:101707-102990:- | gene-YCL011C_NCIM3186 | rna-NM_001178660.1_NCIM3186 | cds-NP_009916.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:98333-99616:- | gene-YCL011C_NCYC1407 | rna-NM_001178660.1_NCYC1407 | cds-NP_009916.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:102503-103786:- | gene-YCL011C_PE2H3 | rna-NM_001178660.1_PE2H3 | cds-NP_009916.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:102463-103746:- | gene-YCL011C_PE2H4 | rna-NM_001178660.1_PE2H4 | cds-NP_009916.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:102075-103358:- | gene-YCL011C_S288C | rna-NM_001178660.1_S288C | cds-NP_009916.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000073.1:47981-49264:+ | gene-YCL011C_SA1 | rna-NM_001178660.1_SA1 | cds-NP_009916.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:97669-98952:- | gene-YCL011C_ThermosaccDry | rna-NM_001178660.1_ThermosaccDry | cds-NP_009916.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:108310-109593:- | gene-YCL011C_VR1 | rna-NM_001178660.1_VR1 | cds-NP_009916.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:96608-97891:- | gene-YCL011C_ZTW1 | rna-NM_001178660.1_ZTW1 | cds-NP_009916.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:126850-128136:- | gene-YCL011C_Sparadoxus | rna-NM_001178660.1_Sparadoxus | cds-NP_009916.1_Sparadoxus | 91.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |